HRPT2 抗体 (AA 119-520)
Quick Overview for HRPT2 抗体 (AA 119-520) (ABIN3043535)
抗原
See all HRPT2 (CDC73) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 119-520
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原理
- Anti-HRPT2/CDC73 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins
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产品特性
- Anti-HRPT2/CDC73 Antibody Picoband® (ABIN3043535). Tested in WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human HRPT2 recombinant protein (Position: Q119-R520). Human HRPT2 shares 100% and 99.8% amino acid (aa) sequence identity with mouse and rat HRPT2, respectively.
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亚型
- IgG
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anti-Parafibromin (CDC73) (AA 132-161) antibody
CDC73 适用: 人 WB, IF, FACS, IHC (p) 宿主: 兔 Polyclonal RB23239 unconjugated
anti-Parafibromin (CDC73) (AA 127-161) antibodyCDC73 适用: 人 WB 宿主: 兔 Polyclonal RB30818 unconjugated
anti-Parafibromin (CDC73) (AA 74-346) antibodyCDC73 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Parafibromin (CDC73) (AA 435-505) antibodyCDC73 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Parafibromin (CDC73) antibodyKD Validated CDC73 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Monoclonal unconjugated Recombinant Antibody
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应用备注
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Western blot, 0.1-0.5 μg/mL, Human
1. "Entrez Gene: CDC73 Cell division cycle 73, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)". 2. Sood R, Bonner TI, Makalowska I, Stephan DA, Robbins CM, Connors TD, Morgenbesser SD, Su K, Faruque MU, Pinkett H, Graham C, Baxevanis AD, Klinger KW, Landes GM, Trent JM, Carpten JD (April 2001). "Cloning and characterization of 13 novel transcripts and the human RGS8 gene from the 1q25 region encompassing the hereditary prostate cancer (HPC1) locus". Genomics 73 (2): 211-22. -
说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- HRPT2 (CDC73) (Parafibromin (CDC73))
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别名
- CDC73
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背景
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Synonyms: Parafibromin,Cell division cycle protein 73 homolog,Hyperparathyroidism 2 protein,CDC73,C1orf28, HRPT2,
Tissue Specificity: Found in adrenal and parathyroid glands, kidney and heart. .
Background: Cell division cycle 73, also known as HRPT2, is a protein which in humans is encoded by the CDC73 gene. This gene encodes a tumor suppressor that is involved in transcriptional and post-transcriptional control pathways. The protein is a component of the the PAF protein complex, which associates with the RNA polymerase II subunit POLR2A and with a histone methyltransferase complex. And this protein appears to facilitate the association of 3' mRNA processing factors with actively-transcribed chromatin. Mutations in this gene have been linked to hyperparathyroidism-jaw tumor syndrome, familial isolated hyperparathyroidism, and parathyroid carcinoma.
Sequence Similarities: Belongs to the CDC73 family.
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分子量
- 61 kDa
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基因ID
- 79577
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UniProt
- Q6P1J9
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途径
- Cellular Response to Molecule of Bacterial Origin, Stem Cell Maintenance
抗原
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