HRPT2 抗体 (AA 119-520)
Quick Overview for HRPT2 抗体 (AA 119-520) (ABIN3043535)
抗原
See all HRPT2 (CDC73) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 119-520
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原理
- Anti-HRPT2/CDC73 Antibody
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交叉反应 (详细)
- No cross-reactivity with other proteins
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产品特性
- Anti-HRPT2/CDC73 Antibody (ABIN3043535). Tested in WB applications. This antibody reacts with Human. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human HRPT2 recombinant protein (Position: Q119-R520). Human HRPT2 shares 100% and 99.8% amino acid (aa) sequence identity with mouse and rat HRPT2, respectively.
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亚型
- IgG
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应用备注
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Western blot, 0.1-0.5 μg/mL, Human
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说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- HRPT2 (CDC73) (Parafibromin (CDC73))
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别名
- CDC73
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背景
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Synonyms: Parafibromin,Cell division cycle protein 73 homolog,Hyperparathyroidism 2 protein,CDC73,C1orf28, HRPT2,
Tissue Specificity: Found in adrenal and parathyroid glands, kidney and heart. .
Background: Cell division cycle 73, also known as HRPT2, is a protein which in humans is encoded by the CDC73 gene. This gene encodes a tumor suppressor that is involved in transcriptional and post-transcriptional control pathways. The protein is a component of the the PAF protein complex, which associates with the RNA polymerase II subunit POLR2A and with a histone methyltransferase complex. And this protein appears to facilitate the association of 3' mRNA processing factors with actively-transcribed chromatin. Mutations in this gene have been linked to hyperparathyroidism-jaw tumor syndrome, familial isolated hyperparathyroidism, and parathyroid carcinoma.
Sequence Similarities: Belongs to the CDC73 family.
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分子量
- 61 kDa
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基因ID
- 79577
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UniProt
- Q6P1J9
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途径
- Cellular Response to Molecule of Bacterial Origin, Stem Cell Maintenance
抗原
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