Ataxin 1 抗体 (C-Term)
Quick Overview for Ataxin 1 抗体 (C-Term) (ABIN3043506)
抗原
See all Ataxin 1 (ATXN1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 778-808, C-Term
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原理
- Anti-Ataxin 1/ATXN1 Antibody Picoband®
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序列
- ESRKLEKSED EPPLTLPKPS LIPQEVKICI E
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交叉反应 （详细）
- No cross-reactivity with other proteins
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产品特性
- Anti-Ataxin 1/ATXN1 Antibody Picoband® (ABIN3043506). Tested in Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the C-terminus of human Ataxin 1, different from the related mouse and rat sequences by one amino acid.
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亚型
- IgG
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anti-Ataxin 1 (ATXN1) (AA 645-815) antibody
ATXN1 适用: 人, 小鼠, 大鼠, 猴 WB, IHC, ELISA, FACS 宿主: 小鼠 Monoclonal 4C7B11 unconjugated
anti-Ataxin 1 (ATXN1) antibodyATXN1 适用: 人 IHC, ELISA, ICC, FACS 宿主: 小鼠 Monoclonal 2F5 unconjugated
anti-Ataxin 1 (ATXN1) (AA 645-815) antibodyATXN1 适用: 人, 小鼠 WB, ELISA, FACS 宿主: 小鼠 Monoclonal 2B8A2 unconjugated
anti-Ataxin 1 (ATXN1) (AA 569-807) antibodyATXN1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Ataxin 1 (ATXN1) (C-Term) antibodyATXN1 适用: 人, 小鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Ataxin 1 (ATXN1) (AA 331-587) antibodyATXN1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Ataxin 1 (ATXN1) (AA 346-475) antibodyATXN1 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Ataxin 1 (ATXN1) (AA 746-761) antibodyATXN1 适用: 小鼠 WB, IF, ICC 宿主: 小鼠 Monoclonal S65-37 unconjugated
anti-Ataxin 1 (ATXN1) (AA 164-197) antibodyATXN1 适用: 小鼠 WB, IHC, IF, IP, ICC 宿主: 小鼠 Monoclonal S76-8 unconjugated
anti-Ataxin 1 (ATXN1) (AA 164-197) antibody (HRP)ATXN1 适用: 小鼠 WB, IHC, IF, IP, ICC 宿主: 小鼠 Monoclonal S76-8 HRP
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应用备注
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Western blot, 0.1-0.5 μg/mL, Mouse, Rat
Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human, Mouse, Rat
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human1. "Entrez Gene: ATXN1 ataxin 1" 2. Tong, X., Gui, H., Jin, F., Heck, B. W., Lin, P., Ma, J., Fondell, J. D., Tsai, C.-C. Ataxin-1 and brother of ataxin-1 are components of the Notch signalling pathway. EMBO Rep. 12: 428-435, 2011. 3. Volz A, Fonatsch C, Ziegler A (Jun 1992). "Regional mapping of the gene for autosomal dominant spinocerebellar ataxia (SCA1) by localizing the closely linked D6S89 locus to 6p24.2----p23.05". Cytogenet Cell Genet 60 (1): 37-9. 4. Volz, A., Boyle, J. M., Cann, H. M., Cottingham, R. W., Orr, H. T., Ziegler, A. Report of the second international workshop on human chromosome 6. Genomics 21: 464, 1994. -
说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- Ataxin 1 (ATXN1)
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别名
- ATXN1
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背景
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Synonyms: Ataxin-1,Spinocerebellar ataxia type 1 protein,ATXN1,ATX1, SCA1,
Tissue Specificity: Widely expressed throughout the body. .
Background: Ataxin-1 is a protein that in humans is encoded by the ATXN1 gene. The ATXN1 gene had been mapped to 6p23 by in situ hybridization. Ataxin-1 (ATXN1), a causative factor for spinocerebellar ataxia type 1 (SCA1), and the related Brother of ATXN1 (BOAT1) are human proteins involved in transcriptional repression. ATXN1 and BOAT1 might participate in several Notch-controlled developmental and pathological processes.
Sequence Similarities: Belongs to the ATXN1 family.
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分子量
- 105 kDa
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UniProt
- P54253
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途径
- Synaptic Membrane
抗原
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