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Annexin V 抗体 (AA 2-320)

ANXA5 适用: 人, 小鼠, 大鼠 WB, IHC, ICC, FACS, IF, IHC (fro) 宿主: 兔 Polyclonal unconjugated

Western Blotting (WB) image for anti-Annexin A5 (ANXA5) (AA 2-320) antibody (ABIN3043502) (Annexin V 抗体 (AA 2-320))

Anti-Annexin V Picoband antibody, IHC(P): Mouse Kidney Tissue (Annexin V 抗体 (AA 2-320))

Anti-Annexin V Picoband antibody, IHC(P): Rat Kidney Tissue (Annexin V 抗体 (AA 2-320))

Anti-Annexin V Picoband antibody, IHC(P): Human Mammary Cancer Tissue (Annexin V 抗体 (AA 2-320))

Anti-Annexin V Picoband antibody, IHC(P): Human Intestinal Cancer Tissue (Annexin V 抗体 (AA 2-320))

5 images

(7 references)

产品编号 ABIN3043502

发货至: 中国

Datasheet as PDF

抗原 See all Annexin V (ANXA5) 抗体

Annexin V (ANXA5) (Annexin A5 (ANXA5))
抗原表位
19

8

7

7

6

4

4

3

2

2

2

2

1

1

1

1

1

1

1

1
AA 2-320
适用
113

58

42

10

5

5

5

4

4

4

3

3

3

2

2

2

1
人, 小鼠, 大鼠
宿主
115

24
兔
Compatible Secondaries
克隆类型
107

30
多克隆
标记
67

18

16

4

3

3

3

3

3

3

2

2

1

1

1

1

1

1

1

1

1

1

1

1
This Annexin V antibody is un-conjugated
应用范围
92

40

36

19

19

19

16

13

11

5

3

2

1

1

1
Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro))

原理

Anti-Annexin V/ANXA5 Antibody Picoband®

交叉反应（详细）

No cross-reactivity with other proteins

产品特性

Anti-Annexin V/ANXA5 Antibody Picoband® (ABIN3043502). Tested in Flow Cytometry, IF, IHC, IHC-F, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

纯化方法

Immunogen affinity purified.

免疫原

E.coli-derived human Annexin V recombinant protein (Position: A2-D320). Human Annexin V shares 94% and 92% amino acid (aa) sequences identity with mouse and rat Annexin V, respectively.

亚型

IgG

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anti-Annexin A5 (ANXA5) (AA 1-320) antibody
ANXA5 适用: 人 WB, ELISA, IP, IHC (p), IF 宿主: 小鼠 Monoclonal 1F4-1A5 unconjugated

anti-Annexin A5 (ANXA5) (AA 1-320) antibody
ANXA5 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C7 unconjugated

anti-Annexin A5 (ANXA5) (AA 1-321) antibody
ANXA5 适用: Cow WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Annexin A5 (ANXA5) (AA 160-320) antibody
ANXA5 适用: 人, 小鼠 WB, ELISA, ICC, FACS 宿主: 小鼠 Monoclonal 3B9B7 unconjugated

anti-Annexin A5 (ANXA5) (AA 1-320) antibody
ANXA5 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated

anti-Annexin A5 (ANXA5) (AA 160-320) antibody
ANXA5 适用: 人 WB, ELISA, FACS 宿主: 小鼠 Monoclonal 3B9F3 unconjugated

anti-Annexin A5 (ANXA5) (AA 88-102), (Middle Region) antibody
ANXA5 适用: 人, 小鼠, 大鼠 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated

anti-Annexin A5 (ANXA5) (AA 88-102) antibody
ANXA5 适用: 人, 小鼠, 大鼠 WB, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Annexin A5 (ANXA5) (AA 2-320) antibody
ANXA5 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated

anti-Annexin A5 (ANXA5) antibody
ANXA5 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated

应用备注

Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human, Mouse, Rat
Immunohistochemistry (Frozen Section), 0.5-1 μg/mL, Human, Rat, -
Immunofluorescence, 2 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 2 μg/mL, Human, Rat
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human1. Bogdanova, N., Horst, J., Chlystun, M., Croucher, P. J. P., Nebel, A., Bohring, A., Todorova, A., Schreiber, S., Gerke, V., Krawczak, M., Markoff, A. A common haplotype of the annexin A5 (ANXA5) gene promoter is associated with recurrent pregnancy loss.Hum. Molec. Genet. 16: 573-578, 2007. 2. Demange, P., Voges, D., Benz, J., Liemann, S., Gottig, P., Berendes, R., Burger, A., Huber, R. Annexin V: the key to understanding ion selectivity and voltage regulation?Trends Biochem. Sci. 19: 272-276, 1994. 3. Sofiadis A, Becker S, Hellman U, Hultin-Rosenberg L, Dinets A, Hulchiy M, Zedenius J, Wallin G, Foukakis T, Höög A, Auer G, Lehtiö J, Larsson C. (April 2012). "Proteomic profiling of follicular and papillary thyroid tumors.". Eur J Endocrinol.. 166 (4): 657-67.

说明

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P) and IHC(F).

限制

仅限研究用
状态

Lyophilized

溶解方式

Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

浓度

500 μg/mL

缓冲液

Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freezing and thawing.

储存条件

4 °C,-20 °C

储存方法

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
Manville, Abbott: "Ancient and modern anticonvulsants act synergistically in a KCNQ potassium channel binding pocket." in: Nature communications, Vol. 9, Issue 1, pp. 3845, (2018) (PubMed).

Sun, Kang, Yao, Chen, Sun, An, Jiang, Wang, Hu: "Dehydrocostus lactone suppressed the proliferation, migration, and invasion of colorectal carcinoma through the downregulation of eIF4E expression." in: Anti-cancer drugs, Vol. 26, Issue 6, pp. 641-8, (2015) (PubMed).

Ji, Li, Wei, Kong, Jin, Chen, Li, Deng: "Effect of celastrol on growth inhibition of prostate cancer cells through the regulation of hERG channel in vitro." in: BioMed research international, Vol. 2015, pp. 308475, (2015) (PubMed).

Xu, Bi, Li, Fang, Zhou, Li, Chi, Wan, Shen: "Morphological and proteomic analyses reveal that unsaturated guluronate oligosaccharide modulates multiple functional pathways in murine macrophage RAW264.7 cells." in: Marine drugs, Vol. 13, Issue 4, pp. 1798-818, (2015) (PubMed).

Hu, Dong, Shi, Deng, Li, Lu: "Evaluation of a novel tetra-functional branched poly(ethylene glycol) crosslinker for manufacture of crosslinked, decellularized, porcine aortic valve leaflets." in: Journal of biomedical materials research. Part B, Applied biomaterials, Vol. 102, Issue 2, pp. 322-36, (2014) (PubMed).

Xiong, Ma, Zhang, Shao, Zhang, Zhou: "Apoptosis induced by ?,?-dimethylacrylshikonin is associated with Bcl-2 and NF-?B in human breast carcinoma MCF-7 cells." in: Oncology letters, Vol. 6, Issue 6, pp. 1789-1793, (2013) (PubMed).

Jin, Liu, Wang, Xu, Yang, Lu, Sun, Hu: "Protective effects of [Gly14]-Humanin on beta-amyloid-induced PC12 cell death by preventing mitochondrial dysfunction." in: Neurochemistry international, Vol. 56, Issue 3, pp. 417-23, (2010) (PubMed).
抗原

Annexin V (ANXA5) (Annexin A5 (ANXA5))

别名

ANXA5 (ANXA5 产品)

背景

Synonyms: Annexin A5,Anchorin CII,Annexin V,Annexin-5,Calphobindin I,CBP-I,Endonexin II,Lipocortin V,Placental anticoagulant protein 4,PP4,Placental anticoagulant protein I,PAP-I,Thromboplastin inhibitor,Vascular anticoagulant-alpha,VAC-alpha,ANXA5,ANX5, ENX2, PP4,
Tissue Specificity: Expressed in all cell types so far analyzed.
Background: Annexin A5 (or annexin V) is a cellular protein in the annexin group. It is mapped to 4q27. Annexin A5 has been proposed to play a role in the inhibition of blood coagulation by competing for phosphatidylserine binding sites with prothrombin and also to inhibit the activity of phospholipase A1. This protein is an anticoagulant protein, it can form a shield around negatively-charged phospholipid molecules, the formation of an annexin A5 shield blocks the entry of phospholipids into coagulation (clotting) reactions. And Annexin A5 can also act as an in inhibitor of the thromboplastin-specific complex, which is involved in the blood coagulation cascade.
Sequence Similarities: Belongs to the annexin family.

分子量

36 kDa

基因ID

308

UniProt

P08758

途径

Apoptosis

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