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Annexin A3 抗体 (Middle Region)

This anti-Annexin A3 antibody is a 兔 多克隆 antibody detecting Annexin A3 in WB, IHC 和 ICC. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN3043501
发货至: 中国

Quick Overview for Annexin A3 抗体 (Middle Region) (ABIN3043501)

抗原

See all Annexin A3 (ANXA3) 抗体
Annexin A3 (ANXA3)

适用

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人, 小鼠, 大鼠

宿主

  • 93
  • 29

克隆类型

  • 86
  • 34
多克隆

标记

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This Annexin A3 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC)
  • 抗原表位

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    AA 153-184, Middle Region

    原理

    Anti-Annexin A3/ANXA3 Antibody Picoband®

    序列

    RKALLTLADG RRDESLKVDE HLAKQDAQIL YK

    交叉反应 (详细)

    No cross-reactivity with other proteins

    产品特性

    Anti-Annexin A3/ANXA3 Antibody Picoband® (ABIN3043501). Tested in IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence in the middle region of human Annexin A3, different from the related mouse sequence by one amino acid, and from the related rat sequence by three amino acids.

    亚型

    IgG
  • 应用备注

    Immunohistochemistry (Frozen Section), 0.5-1 μg/mL
    Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL
    Western blot, 0.1-0.5 μg/mL
    Immunocytochemistry , 0.5-1 μg/mL
    1. Bianchi C, et al. Primary cell cultures from human renal cortex and renal-cell carcinoma evidence a differential expression of two spliced isoforms of Annexin A3. Am J Pathol, 2010 Apr. 2. Jung EJ, et al. Decreased annexin A3 expression correlates with tumor progression in papillary thyroid cancer. Proteomics Clin Appl, 2010 May. 3. Yan X, et al. Increased expression of annexin A3 is a mechanism of platinum resistance in ovarian cancer. Cancer Res, 2010 Feb 15.

    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P) and IHC(F).

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • 抗原

    Annexin A3 (ANXA3)

    别名

    ANXA3

    背景

    Synonyms: Annexin A3,35-alpha calcimedin,Annexin III,Annexin-3,Inositol 1,2-cyclic phosphate 2-phosphohydrolase,Lipocortin III,Placental anticoagulant protein III,PAP-III,ANXA3,ANX3,

    Tissue Specificity: Expressed in all tissues tested including brain, heart, kidney, liver, lung, muscle, ovary, skin, spleen and thymus. .

    Background: Annexin A3 is a protein that in humans is encoded by the Annexin A3 gene. The Annexin A3 gene contains 13 exons and spans 58 kb of genomic DNA. The Annexin A3 gene is mapped to 4q21. It is abnormally expressed in fetuses of both IVF and ICSI, which may contribute to the increase risk of birth defects in these ART. This gene encodes a member of the annexin family. Members of this calcium-dependent phospholipid-binding protein family play a role in the regulation of cellular growth and in signal transduction pathways. This protein functions in the inhibition of phospholipase A2 and cleavage of inositol 1,2-cyclic phosphate to form inositol 1-phosphate. This protein may also play a role in anti-coagulation.

    Sequence Similarities: Belongs to the annexin family.

    分子量

    36 kDa

    基因ID

    306

    UniProt

    P12429
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