DDB2 抗体 (AA 1-115)
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- 抗原 See all DDB2 抗体
- DDB2 (Damage-Specific DNA Binding Protein 2, 48kDa (DDB2))
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抗原表位
- AA 1-115
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This DDB2 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 原理
- Rabbit IgG polyclonal antibody for DNA damage-binding protein 2(DDB2) detection. Tested with WB in Human.
- 交叉反应 (详细)
- No cross reactivity with other proteins.
- 产品特性
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Rabbit IgG polyclonal antibody for DNA damage-binding protein 2(DDB2) detection. Tested with WB in Human.
Gene Name: damage-specific DNA binding protein 2
Protein Name: DNA damage-binding protein 2 - 纯化方法
- Immunogen affinity purified.
- 免疫原
- E.coli-derived human DDB2 recombinant protein (Position: M1-T115). Human DDB2 shares 58.3% amino acid (aa) sequence identity with mouse DDB2.
- 亚型
- IgG
- Top Product
- Discover our top product DDB2 Primary Antibody
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- 应用备注
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WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human
Notes: Tested Species: Species with positive results.
Other applications have not been tested. Optimal dilutions should be determined by end users. - 说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- 浓度
- 500 μg/mL
- 缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
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At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
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- 抗原
- DDB2 (Damage-Specific DNA Binding Protein 2, 48kDa (DDB2))
- 别名
- DDB2 (DDB2 产品)
- 别名
- 2610043A19Rik antibody, si:dkey-45f10.3 antibody, DDBB antibody, UV-DDB2 antibody, damage specific DNA binding protein 2 antibody, damage-specific DNA binding protein 2 antibody, DDB2 antibody, ddb2 antibody, Ddb2 antibody
- 背景
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DNA damage-binding protein 2 is a protein that in humans is encoded by the DDB2 gene. This gene encodes a protein that is necessary for the repair of ultraviolet light-damaged DNA. This protein is the smaller subunit of a heterodimeric protein complex that participates in nucleotide excision repair, and this complex mediates the ubiquitylation of histones H3 and H4, which facilitates the cellular response to DNA damage. And this subunit appears to be required for DNA binding. Mutations in this gene cause xeroderma pigmentosum complementation group E, a recessive disease that is characterized by an increased sensitivity to UV light and a high predisposition for skin cancer development, in some cases accompanied by neurological abnormalities. Two transcript variants encoding different isoforms have been found for this gene.
Synonyms: damage-specific DNA binding protein 2 antibody|Damage-specific DNA-binding protein 2 antibody|DDB p48 subunit antibody|Ddb2 antibody| DDB2_HUMAN antibody|DDBb antibody|DNA damage-binding protein 2 antibody|UV-damaged DNA-binding protein 2 antibody|UV-DDB 2 antibody| Xeroderma pigmentosum group E protei antibody - 基因ID
- 1643
- UniProt
- Q92466
- 途径
- DNA Damage Repair
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