Decorin 抗体 (AA 31-359)
(3 references)Quick Overview for Decorin 抗体 (AA 31-359) (ABIN3043487)
抗原
See all Decorin (DCN) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 31-359
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原理
- Anti-Decorin/DCN Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins
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产品特性
- Anti-Decorin/DCN Antibody Picoband® (ABIN3043487). Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human Decorin recombinant protein (Position: D31-K359). Human Decorin shares 80% and 77% amino acid (aa) sequences identity with mouse and rat Decorin, respectively.
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亚型
- IgG
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anti-Decorin (DCN) (AA 31-359) antibody
DCN 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Decorin (DCN) (AA 1-359) antibodyDCN 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 3H4-1F4 unconjugated
anti-Decorin (DCN) (AA 263-324) antibodyDCN 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 5E8E7 unconjugated
anti-Decorin (DCN) (Internal Region) antibodyDCN 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Decorin (DCN) antibodyDCN 适用: 人 WB, IP, IHC (p), IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Decorin (DCN) (AA 122-150) antibodyDCN 适用: 人, 小鼠 WB, IHC (p), FACS 宿主: 兔 Polyclonal RB19595 unconjugated
anti-Decorin (DCN) (AA 31-359) antibodyDCN 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Decorin (DCN) (AA 212-336) antibodyDCN 适用: 人 IHC, StM 宿主: 小鼠 Monoclonal DCN-3523 unconjugated
anti-Decorin (DCN) antibodyDCN 适用: 人, 小鼠, 大鼠 IF 宿主: 兔 Polyclonal unconjugated
anti-Decorin (DCN) (AA 1-360) antibodyDCN 适用: 人 WB, ELISA, IHC, IHC (p) 宿主: 小鼠 Monoclonal 3H4-1F4 unconjugated
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应用备注
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Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human
Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
1. Danielson, K. G., Fazzio, A., Cohen, I., Cannizzaro, L. A., Eichstetter, I., Iozzo, R. V. : The human decorin gene: intron-exon organization, discovery of two alternatively spliced exons in the 5-prime untranslated region, and mapping of the gene to chromosome 12q23. Genomics 15: 146-160, 1993. 2. Vetter, U., Vogel, W., Just, W., Young, M. F., Fisher, L. W. : Human decorin gene: intron-exon junctions and chromosomal localization. Genomics 15: 161-168, 1993. 3. Scholzen, T., Solursh, M., Suzuki, S., Reiter, R., Morgan, J. L., Buchberg, A. M., Siracusa, L. D., Iozzo, R. V. : The murine decorin: complete cDNA cloning, genomic organization, chromosomal assignment, and expression during organogenesis and tissue differentiation. J. Biol. Chem. 269: 28270-28281, 1994. -
说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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: "Overexpression of decorin promoted angiogenesis in diabetic cardiomyopathy via IGF1R-AKT-VEGF signaling." in: Scientific reports, Vol. 7, pp. 44473, (2018) (PubMed).
: "An Animal Model of Modic Changes by Embedding Autogenous Nucleus Pulposus inside Subchondral Bone of Lumbar Vertebrae." in: Scientific reports, Vol. 6, pp. 35102, (2016) (PubMed).
: "The effect of electroacupuncture on the extracellular matrix synthesis and degradation in a rabbit model of disc degeneration." in: Evidence-based complementary and alternative medicine : eCAM, Vol. 2014, pp. 731395, (2014) (PubMed).
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: "Overexpression of decorin promoted angiogenesis in diabetic cardiomyopathy via IGF1R-AKT-VEGF signaling." in: Scientific reports, Vol. 7, pp. 44473, (2018) (PubMed).
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- Decorin (DCN)
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别名
- DCN
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背景
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Synonyms: Decorin,Bone proteoglycan II,PG-S2,PG40,DCN,SLRR1B,
Tissue Specificity: Expressed at low levels in the lung, kidney and spleen.
Background: Decorin is a protein that in humans is encoded by the DCN gene. This gene is mapped to 12q21.3. It belongs to the small leucine-rich proteoglycan (SLRP) family and consists of a protein core containing leucine repeats with a glycosaminoglycan (GAG) chain consisting of either chondroitin sulfate (CS) or dermatan sulfate (DS). Decorin is a small cellular or pericellular matrix proteoglycan and is closely related in structure to biglycan protein. This protein is a component of connective tissue, binds to type I collagen fibrils, and plays a role in matrix assembly. And it also may play a role in epithelial/mesenchymal interactions during organ development and shaping. Decorin has been shown to have anti-tumorigenic properties in an experimental murine tumor model and is capable of suppressing the growth of various tumor cell lines.
Sequence Similarities: Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily.
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分子量
- 40-50 kDa, 80-140 kDa.
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基因ID
- 1634
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UniProt
- P07585
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途径
- Glycosaminoglycan Metabolic Process
抗原
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