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- 抗原 See all CD82 抗体
- CD82
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抗原表位
- AA 98-267
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CD82 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC)
- 原理
- Anti-CD82 Antibody Picoband®
- 交叉反应 （详细）
- No cross-reactivity with other proteins
- 产品特性
- Anti-CD82 Antibody Picoband® (ABIN3043486). Tested in IHC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
- 纯化方法
- Immunogen affinity purified.
- 免疫原
- E.coli-derived human CD82 recombinant protein (Position: A98-Y267). Human CD82 shares 69% and 67% amino acid (aa) sequences identity with mouse and rat CD82, respectively.
- 亚型
- IgG
- Top Product
- Discover our top product CD82 Primary Antibody
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anti-CD82 (CD82) antibody
CD82 适用: 人 WB, FACS, IHC (p), IP, ICC, Func 宿主: 小鼠 Monoclonal C33 unconjugated
anti-CD82 (CD82) antibodyCD82 适用: 人 WB, IHC, IF 宿主: 兔 Monoclonal unconjugated
anti-CD82 (CD82) (AA 239-267), (C-Term) antibodyCD82 适用: 人, 小鼠 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB02073-02074 unconjugated
anti-CD82 (CD82) antibodyCD82 适用: 人 IHC, FACS 宿主: 小鼠 Monoclonal B-L2 unconjugated
anti-CD82 (CD82) (AA 111-228) antibodyCD82 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-CD82 (CD82) (AA 1-267) antibodyCD82 适用: 人 ELISA, PLA 宿主: 小鼠 Monoclonal 4F2 unconjugated
anti-CD82 (CD82) (C-Term) antibodyCD82 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-CD82 (CD82) antibody (Biotin)CD82 适用: 人 WB, FACS, IHC (p), IP, ICC 宿主: 小鼠 Monoclonal C33 Biotin
anti-CD82 (CD82) antibody (FITC)CD82 适用: 人 FACS 宿主: 小鼠 Monoclonal C33 FITC
anti-CD82 (CD82) antibody (APC)CD82 适用: 人 FACS 宿主: 小鼠 Monoclonal C33 APC
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- 应用备注
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Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human
Western blot, 0.1-0.5 μg/mL, Human
1. Dong, J.-T., Lamb, P. W., Rinker-Schaeffer, C. W., Vukanovic, J., Ichikawa, T., Isaacs, J. T., Barrett, J. C. : KAI1, a metastasis suppressor gene for prostate cancer on human chromosome 11p11.2. Science 268: 884-886, 1995. 2. Mashimo, T., Watabe, M., Hirota, S., Hosobe, S., Miura, K., Tegtmeyer, P. J., Rinker-Shaeffer, C. W., Watabe, K. : The expression of the KAI1 gene, a tumor metastasis suppressor, is ly activated by p53. Proc. Nat. Acad. Sci. 95: 11307-11311, 1998. 3. Miyazaki, T., Kato, H., Shitara, Y., Yoshikawa, M., Tajima, K., Masuda, N., Shouji, H., Tsukada, K., Nakajima, T., Kuwano, H. : Mutation and expression of the metastasis suppressor gene KAI1 in esophageal squamous cell carcinoma. Cancer 89: 955-962, 2000. 4. Jee, B. K., Park, K. M., Surendran, S., Lee, W. K., Han, C. W., Kim, Y. S., Lim, Y. : KAI1/CD82 suppresses tumor invasion by MMP9 inactivation via TIMP1 up-regulation in the H1299 human lung carcinoma cell line. Biochem. Biophys. Res. Commun. 342: 655-661, 2006. - 说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- 浓度
- 500 μg/mL
- 缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C,-20 °C
- 储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- 抗原
- CD82
- 别名
- CD82 (CD82 产品)
- 背景
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Synonyms: CD82 antigen,C33 antigen,IA4,Inducible membrane protein R2,Metastasis suppressor Kangai-1,Suppressor of tumorigenicity 6 protein,Tetraspanin-27,Tspan-27,CD82,CD82,KAI1, SAR2, ST6, TSPAN27,
Tissue Specificity: Lymphoid specific.
Background: CD82 (Cluster of Differentiation 82), also named KAI1, is a protein that in humans encoded by the CD82 gene. The gene is mapped to 11p11.2. This metastasis suppressor gene product is a membrane glycoprotein that is a member of the transmembrane 4 superfamily. Expression of this gene has been shown to be downregulated in tumor progression of human cancers and can be activated by p53 through a consensus binding sequence in the promoter. The expression of CD82 protein appears to be correlated with lymph node metastasis in esophageal squamous cell carcinoma (ESCC). And the CD82 overexpression can suppress tumor invasiveness and metastatic potential by inducing MMP9 inactivation via upregulation of TIMP1.
Sequence Similarities: Belongs to the tetraspanin (TM4SF) family.
- 分子量
- 30-36 kDa
- 基因ID
- 3732
- UniProt
- P27701
- 途径
- p53 Pathway
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