Cyclin A1 抗体 (AA 64-263)
(2 references)Quick Overview for Cyclin A1 抗体 (AA 64-263) (ABIN3043480)
抗原
See all Cyclin A1 (CCNA1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 64-263
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原理
- Anti-Cyclin A1/CCNA1 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins
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产品特性
- Anti-Cyclin A1/CCNA1 Antibody Picoband® (ABIN3043480). Tested in IF, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human Cyclin A1 recombinant protein (Position: D64-E263). Human Cyclin A1 shares 78.5% and 79.5% amino acid (aa) sequence identity with mouse and rat Cyclin A1, respectively.
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亚型
- IgG
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anti-Cyclin A1 (CCNA1) antibody
CCNA1 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Cyclin A1 (CCNA1) antibodyCCNA1 适用: 人, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Cyclin A1 (CCNA1) (AA 211-310) antibodyCCNA1 适用: 小鼠, 大鼠, 绵羊 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Cyclin A1 (CCNA1) (AA 1-464) antibodyCCNA1 适用: 人 WB, ELISA, PLA 宿主: 小鼠 Monoclonal 4A11-5B5 unconjugated
anti-Cyclin A1 (CCNA1) (C-Term) antibodyCCNA1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Cyclin A1 (CCNA1) (C-Term) antibodyCCNA1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Cyclin A1 (CCNA1) antibodyCCNA1 适用: 非洲爪蟾 WB 宿主: 小鼠 Monoclonal XLA1-3 unconjugated
anti-Cyclin A1 (CCNA1) (AA 1-230) antibodyCCNA1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Cyclin A1 (CCNA1) (C-Term) antibodyCCNA1 适用: 人, 小鼠, 大鼠, Cow, 兔, 小鸡, 犬, Pig WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-Cyclin A1 (CCNA1) (AA 183-430) antibodyCCNA1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.1-0.5 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
1. "Entrez Gene: CCNA1 cyclin A1". 2. Yang R, Morosetti R, Koeffler HP (March 1997). "Characterization of a second human cyclin A that is highly expressed in testis and in several leukemic cell lines".Cancer Res. 57 (5): 913-20. -
说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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: "Autocrine fibronectin from differentiating mesenchymal stem cells induces the neurite elongation in vitro and promotes nerve fiber regeneration in transected spinal cord injury." in: Journal of biomedical materials research. Part A, Vol. 104, Issue 8, pp. 1902-11, (2017) (PubMed).
: "Overexpression of miR-30a in lung adenocarcinoma A549 cell line inhibits migration and invasion via targeting EYA2." in: Acta biochimica et biophysica Sinica, Vol. 48, Issue 3, pp. 220-8, (2016) (PubMed).
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: "Autocrine fibronectin from differentiating mesenchymal stem cells induces the neurite elongation in vitro and promotes nerve fiber regeneration in transected spinal cord injury." in: Journal of biomedical materials research. Part A, Vol. 104, Issue 8, pp. 1902-11, (2017) (PubMed).
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- Cyclin A1 (CCNA1)
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别名
- CCNA1
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背景
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Synonyms: Cyclin-A1,CCNA1,
Tissue Specificity: Very high levels in testis and very low levels in brain. Also found in myeloid leukemia cell lines.
Background: Cyclin-A1 is a protein that in humans is encoded by the CCNA1 gene. The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. The cyclin encoded by this gene was shown to be expressed in testis and brain, as well as in several leukemic cell lines, and is thought to primarily function in the control of the germline meiotic cell cycle. This cyclin binds both CDK2 and CDC2 kinases, which give two distinct kinase activities, one appearing in S phase, the other in G2, and thus regulate separate functions in cell cycle. Also this cyclin was found to bind to important cell cycle regulators, such as Rb family proteins, transcription factor E2F-1, and the p21 family proteins. Multiple transcript variants encoding different isoforms have been found for this gene.
Sequence Similarities: Belongs to the cyclin family. Cyclin AB subfamily.
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分子量
- 55 kDa
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基因ID
- 8900
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UniProt
- P78396
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途径
- Apoptosis, Cell Division Cycle, AMPK Signaling, Mitotic G1-G1/S Phases, DNA Replication, M Phase, Synthesis of DNA
抗原
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