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CCL4 抗体 (AA 24-92)

This 兔 多克隆 antibody specifically detects CCL4 in WB 和 ELISA. It exhibits reactivity toward 人.
产品编号 ABIN3043477
发货至: 中国
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北京 101111
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Room 801-803
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Quick Overview for CCL4 抗体 (AA 24-92) (ABIN3043477)

抗原

See all CCL4 抗体
CCL4 (Chemokine (C-C Motif) Ligand 4 (CCL4))

适用

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宿主

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克隆类型

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多克隆

标记

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This CCL4 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA
  • 抗原表位

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    AA 24-92

    原理

    Anti-Macrophage Inflammatory Protein 1 beta/CCL4 Antibody

    交叉反应 (详细)

    No cross-reactivity with other proteins

    产品特性

    Anti-Macrophage Inflammatory Protein 1 beta/CCL4 Antibody (ABIN3043477). Tested in ELISA, WB applications. This antibody reacts with Human. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E. coli-derived human CCL4 recombinant protein (Position: A24-N92). Human CCL4 shares 76.8% and 79.7% amino acid (aa) sequence identity with mouse and rat CCL4, respectively.

    亚型

    IgG
  • 应用备注

    ELISA, 0.1-0.5 μg/mL, -
    Western blot, 0.1-0.5 μg/mL, Human

    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • 抗原

    CCL4 (Chemokine (C-C Motif) Ligand 4 (CCL4))

    别名

    CCL4

    背景

    Synonyms: C-C motif chemokine 4,G-26 T-lymphocyte-secreted protein,HC21,Lymphocyte activation gene 1 protein,LAG-1,MIP-1-beta (1-69),Macrophage inflammatory protein 1-beta,MIP-1-beta,PAT 744,Protein H400,SIS-gamma,Small-inducible cytokine A4,T-cell activation protein 2,ACT-2,MIP-1-beta (3-69),CCL4,LAG1, MIP1B, SCYA4,

    Tissue Specificity: Synthesized in liver and selectively concentrated in bone matrix. Secreted in plasma. It is also found in dentin in much higher quantities than other plasma proteins.

    Background: Chemokine (C-C motif) ligand 4, also known as CCL4, is a protein which in human is encoded by the CCL4 gene. By analysis of somatic cell hybrids and by in situ hybridization, the CCL4 gene was assigned to 17q21-q23. It is a CC chemokine with specificity for CCR5 receptors. And it is a chemoattractant for natural killer cells, monocytes and a variety of other immune cells. CCL4 is a major HIV-suppressive factor produced by CD8+ T cells. Performing-low memory CD8+ T cells that normally synthesize CCL4. Based on functional analysis of CCL4, one or more additional beta chemokine receptors that transduce CCL4 signals must also exist. MIP-1alpha and CCL4 have been shown to lack affinity for the erythrocyte surface chemokine receptor/Duffy antigen that binds many alpha as well as beta chemokines (11, 14).

    Sequence Similarities: Belongs to the intercrine beta (chemokine CC) family.

    分子量

    11 kDa

    基因ID

    6351

    UniProt

    P13236
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