CAPNL1 抗体 (AA 396-555)
(3 references)-
- 抗原 See all CAPNL1 抗体
- CAPNL1 (Calpain 1, Large Subunit (CAPNL1))
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抗原表位
- AA 396-555
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CAPNL1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 原理
- Rabbit IgG polyclonal antibody for Calpain-1 catalytic subunit(CAPN1) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
- 交叉反应 （详细）
- No cross reactivity with other proteins.
- 产品特性
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Rabbit IgG polyclonal antibody for Calpain-1 catalytic subunit(CAPN1) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
Gene Name: calpain 1, (mu/I) large subunit
Protein Name: Calpain-1 catalytic subunit - 纯化方法
- Immunogen affinity purified.
- 免疫原
- E.coli-derived human Calpain 1 recombinant protein (Position: Q396-A555). Human Calpain 1 shares 86% amino acid (aa) sequence identity with both mouse and rat Calpain 1.
- 亚型
- IgG
- Top Product
- Discover our top product CAPNL1 Primary Antibody
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anti-Calpain 1, Large Subunit (CAPNL1) (AA 20-330) antibody
CAPNL1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Calpain 1, Large Subunit (CAPNL1) (AA 501-714) antibodyCAPNL1 适用: 人 WB, ELISA, IHC, FACS 宿主: 小鼠 Monoclonal 5B2G10 unconjugated
anti-Calpain 1, Large Subunit (CAPNL1) (AA 387-694) antibodyCAPNL1 适用: 大鼠 WB, IHC, IF/ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Calpain 1, Large Subunit (CAPNL1) (AA 501-714) antibodyCAPNL1 适用: 人 WB, ELISA, IHC, FACS, ICC, Neut 宿主: 小鼠 Monoclonal 1E6G9 unconjugated
anti-Calpain 1, Large Subunit (CAPNL1) (AA 312-326), (Middle Region) antibodyCAPNL1 适用: 人, 小鼠, 大鼠 WB, IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Calpain 1, Large Subunit (CAPNL1) (AA 387-694) antibodyCAPNL1 适用: 小鼠 WB, IHC, IF/ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Calpain 1, Large Subunit (CAPNL1) (AA 20-330), (Catalytic Subunit) antibodyCAPNL1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Calpain 1, Large Subunit (CAPNL1) (AA 1-714), (Catalytic Subunit) antibodyCAPNL1 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Calpain 1, Large Subunit (CAPNL1) (AA 1-420) antibodyCAPNL1 适用: 人 WB, IHC (p), FACS 宿主: 小鼠 Monoclonal 1376CT809-24-85 unconjugated
anti-Calpain 1, Large Subunit (CAPNL1) (AA 1-714) antibodyCAPNL1 适用: 人 WB, IP, IF 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Mouse, Rat, The detection limit for Calpain 1 is approximately 0.1 ng/lane under reducing conditions.
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users. - 说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- 浓度
- 500 μg/mL
- 缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
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At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
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: "Over-expression of calpastatin inhibits calpain activation and attenuates post-infarction myocardial remodeling." in: PLoS ONE, Vol. 10, Issue 3, pp. e0120178, (2015) (PubMed).
: "Fibrosis, adipogenesis, and muscle atrophy in congenital muscular torticollis." in: Medicine, Vol. 93, Issue 23, pp. e138, (2014) (PubMed).
: "Suppression of NHE1 by small interfering RNA inhibits HIF-1?-induced angiogenesis in vitro via modulation of calpain activity." in: Microvascular research, Vol. 81, Issue 2, pp. 160-8, (2011) (PubMed).
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: "Over-expression of calpastatin inhibits calpain activation and attenuates post-infarction myocardial remodeling." in: PLoS ONE, Vol. 10, Issue 3, pp. e0120178, (2015) (PubMed).
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- 抗原
- CAPNL1 (Calpain 1, Large Subunit (CAPNL1))
- 别名
- CAPN1 (CAPNL1 产品)
- 别名
- CANP antibody, CANP1 antibody, CANPL1 antibody, muCANP antibody, muCL antibody, Capa-1 antibody, Capa1 antibody, mu-calpin antibody, si:ch211-203k12.4 antibody, si:dkeyp-101g1.3 antibody, calpain antibody, calpain 1 antibody, calpain 1, (mu/I) large subunit antibody, calpain 1, (mu/I) large subunit b antibody, calpain 11 antibody, CAPN1 antibody, Capn1 antibody, capn1 antibody, capn1b antibody, CAPN11 antibody
- 背景
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CAPN1 is also known as CANP or muCL. The calpains, calcium-activated neutral proteases, are nonlysosomal, intracellular cysteine proteases. The mammalian calpains include ubiquitous, stomach-specific, and muscle-specific proteins. The ubiquitous enzymes consist of heterodimers with distinct large, catalytic subunits associated with a common small, regulatory subunit. This gene encodes the large subunit of the ubiquitous enzyme, calpain 1. Several transcript variants encoding two different isoforms have been found for this gene.
Synonyms: Ca2 activated neutral protease antibody|Calcium activated neutral proteinase 1 antibody|Calcium activated neutral proteinase antibody|Calcium activated neutral proteinase small subunit antibody|Calcium dependent protease small subunit 1 antibody|Calcium dependent protease small subunit antibody|Calcium-activated neutral proteinase 1 antibody|Calpain 1 (mu/I) large subunit antibody|Calpain 1 antibody|Calpain 1 catalytic subunit antibody|Calpain 1 large subunit antibody|Calpain 1, (mu/I) large subunit antibody|Calpain Large Polypeptide L1 antibody|Calpain mu type antibody|Calpain mu-type antibody|Calpain regulatory subunit antibody|Calpain small subunit 1 antibody|Calpain, large polypeptide L1 antibody|Calpain-1 catalytic subunit antibody|Calpain-1 large subunit antibody|Calpain1 antibody|CAN1_HUMAN antibody|CANP 1 antibody|CANP antibody|CANP small subunit antibody|CANP1 antibody|CANPL 1 antibody|CANPL1 antibody|CAPN 1 antibody|CAPN1 antibody|Cell proliferation inducing protein 30 antibody|Cell proliferation-inducing gene 30 protein antibody|Micromolar Calpain antibody|Micromolar-calpain antibody|Mu Calpain antibody|muCANP antibody|muCL antibody - 基因ID
- 823
- UniProt
- P07384
- 途径
- Apoptosis
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