LOXL2 抗体 (C-Term)
Quick Overview for LOXL2 抗体 (C-Term) (ABIN3043464)
抗原
See all LOXL2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 739-770, C-Term
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原理
- Anti-LOXL2 Antibody Picoband®
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序列
- HRIWMYNCHI GGSFSEETEK KFEHFSGLLN NQ
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-LOXL2 Antibody Picoband® (ABIN3043464). Tested in WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the C-terminus of human LOXL2, different from the related mouse and rat sequences by four amino acids.
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亚型
- IgG
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anti-Lysyl Oxidase-Like 2 (LOXL2) antibody
KO Validated LOXL2 适用: 人 WB, IHC, ELISA, ICC, IHC (p), IF 宿主: 兔 Polyclonal unconjugated
anti-Lysyl Oxidase-Like 2 (LOXL2) (AA 544-751) antibodyLOXL2 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Lysyl Oxidase-Like 2 (LOXL2) antibodyLOXL2 适用: 人 WB, IHC, ELISA, IF, FACS 宿主: 兔 Monoclonal 2E5 unconjugated Recombinant Antibody
anti-Lysyl Oxidase-Like 2 (LOXL2) (Internal Region) antibodyLOXL2 适用: 人, 小鼠, 大鼠, Cow, 犬, 马, 兔, 豚鼠, 猴 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Lysyl Oxidase-Like 2 (LOXL2) (AA 675-773) antibodyLOXL2 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 5D2 unconjugated
anti-Lysyl Oxidase-Like 2 (LOXL2) (AA 53-160) antibodyLOXL2 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Lysyl Oxidase-Like 2 (LOXL2) (AA 27-121) antibodyLOXL2 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Lysyl Oxidase-Like 2 (LOXL2) (AA 675-773) antibodyLOXL2 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Lysyl Oxidase-Like 2 (LOXL2) (AA 505-774) antibodyLOXL2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Lysyl Oxidase-Like 2 (LOXL2) (AA 553-761) antibodyLOXL2 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
1. "Entrez Gene: LOXL2 lysyl oxidase-like 2". 2. Bignon M, Pichol-Thievend C, Hardouin J, Malbouyres M, Bréchot N, Nasciutti L, Barret A, Teillon J, Guillon E, Etienne E, Caron M, Joubert-Caron R, Monnot C, Ruggiero F, Muller L, Germain S (2011). "Lysyl oxidase-like protein-2 regulates sprouting angiogenesis and type IV collagen assembly in the endothelial basement membrane".Blood 118: 3979-89. 3. Jourdan-Le Saux C, Le Saux O, Donlon T, Boyd CD, Csiszar K (Jul 1998). "The human lysyl oxidase-related gene (LOXL2) maps between markers D8S280 and D8S278 on chromosome 8p21.2-p21.3". Genomics 51 (2): 305-7. -
说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- LOXL2 (Lysyl Oxidase-Like 2 (LOXL2))
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别名
- LOXL2
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背景
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Synonyms: Lysyl oxidase homolog 2,1.4.3.13,Lysyl oxidase-like protein 2,Lysyl oxidase-related protein 2,Lysyl oxidase-related protein WS9-14,LOXL2,
Tissue Specificity: Expressed in many tissues. Highest expression in reproductive tissues, placenta, uterus and prostate. Up- regulated in a number of cancers cells and tissues.
Background: Lysyl oxidase homolog 2?is an?enzyme?that in humans is encoded by the?LOXL2?gene. This gene encodes a member of the lysyl oxidase gene family. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyses the first step in the formation of crosslinks in collagens and elastin. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function. The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member of the family.?LOXL2 can also crosslink?collagen type IV?and hence influence the sprouting of new?blood?vessels.
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分子量
- 105 kDa
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基因ID
- 4017
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UniProt
- Q9Y4K0
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途径
- Chromatin Binding
抗原
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