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- 抗原 See all LOXL2 抗体
- LOXL2 (Lysyl Oxidase-Like 2 (LOXL2))
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抗原表位
- AA 27-121
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This LOXL2 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- 交叉反应
- 人, 小鼠, 大鼠
- 纯化方法
- >95%, Protein G purified
- 免疫原
- Recombinant Human Lysyl oxidase homolog 2 protein (27-121AA)
- 亚型
- IgG
- Top Product
- Discover our top product LOXL2 Primary Antibody
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anti-Lysyl Oxidase-Like 2 (LOXL2) antibody
KO Validated LOXL2 适用: 人 WB, ELISA, IHC, ICC, IHC (p), IF 宿主: 兔 Polyclonal unconjugated
anti-Lysyl Oxidase-Like 2 (LOXL2) (AA 544-751) antibodyLOXL2 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Lysyl Oxidase-Like 2 (LOXL2) antibodyLOXL2 适用: 人 WB, ELISA, IHC, IF, FACS 宿主: 兔 Monoclonal 2E5 unconjugated Recombinant Antibody
anti-Lysyl Oxidase-Like 2 (LOXL2) (AA 675-773) antibodyLOXL2 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 5D2 unconjugated
anti-Lysyl Oxidase-Like 2 (LOXL2) (AA 53-160) antibodyLOXL2 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Lysyl Oxidase-Like 2 (LOXL2) (AA 675-773) antibodyLOXL2 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Lysyl Oxidase-Like 2 (LOXL2) (Internal Region) antibodyLOXL2 适用: 人, 小鼠, 大鼠, Cow, 犬, 马, 兔, 豚鼠, 猴, Gorilla, Orang-Utan IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Lysyl Oxidase-Like 2 (LOXL2) (AA 505-774) antibodyLOXL2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Lysyl Oxidase-Like 2 (LOXL2) (AA 553-761) antibodyLOXL2 适用: 大鼠 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-Lysyl Oxidase-Like 2 (LOXL2) (AA 434-546) antibodyLOXL2 适用: 大鼠 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 - 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- LOXL2 (Lysyl Oxidase-Like 2 (LOXL2))
- 别名
- LOXL2 (LOXL2 产品)
- 别名
- LOR2 antibody, WS9-14 antibody, CG4402 antibody, Dmel\\CG4402 antibody, Dmloxl-2 antibody, dmlox-2 antibody, 1110004B06Rik antibody, 4930526G11Rik antibody, 9430067E15Rik antibody, GB13360 antibody, lox2-like antibody, LOXL2 antibody, lor2 antibody, loxl-2 antibody, ws9-14 antibody, im:7136137 antibody, si:dkeyp-32b1.1 antibody, wu:fk12g04 antibody, zgc:158414 antibody, lysyl oxidase like 2 antibody, lysyl oxidase-like 2 antibody, lysyl oxidase homolog 4 antibody, lysyl oxidase like 2 L homeolog antibody, lysyl oxidase-like 2b antibody, LOXL2 antibody, lox2 antibody, Loxl2 antibody, LOC408544 antibody, loxl2.L antibody, loxl2 antibody, loxl2b antibody
- 背景
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Background: Mediates the post-translational oxidative deamination of lysine residues on target proteins leading to the formation of deaminated lysine (allysine). When secreted in extracellular matrix, promotes cross-linking of extracellular matrix proteins by mediating oxidative deamination of peptidyl lysine residues in precursors to fibrous collagen and elastin. Acts as a regulator of sprouting angiogenesis, probably via collagen IV scaffolding. When nuclear, acts as a transcription corepressor and specifically mediates deamination of trimethylated \\\'Lys-4\\\' of histone H3 (H3K4me3), a specific tag for epigenetic transcriptional activation. Involved in epithelial to mesenchymal transition (EMT) via interaction with SNAI1 and participates in repression of E-cadherin, probably by mediating deamination of histone H3. Also involved in E-cadherin repression following hypoxia, a hallmark of epithelial to mesenchymal transition believed to amplify tumor aggressiveness, suggesting that it may play a role in tumor progression. Acts as a regulator of chondrocyte differentiation, probably by regulating expression of factors that control chondrocyte differentiation.
Aliases: LOR 2 antibody, LOR2 antibody, LOX L2 antibody, LOXL 2 antibody, LOXL2 antibody, LOXL2_HUMAN antibody, Lysyl oxidase homolog 2 antibody, Lysyl oxidase like 2 antibody, Lysyl oxidase like protein 2 antibody, Lysyl oxidase related 2 antibody, Lysyl oxidase related protein 2 antibody, Lysyl oxidase related protein WS9 14 antibody, Lysyl oxidase-like protein 2 antibody, Lysyl oxidase-related protein 2 antibody, Lysyl oxidase-related protein WS9-14 antibody, WS9 14 antibody
- UniProt
- Q9Y4K0
- 途径
- Chromatin Binding
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