PTPN2 抗体 (AA 1-330)
Quick Overview for PTPN2 抗体 (AA 1-330) (ABIN3043447)
抗原
See all PTPN2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-330
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原理
- Anti-TCPTP/PTPN2 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins
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产品特性
- Anti-TCPTP/PTPN2 Antibody Picoband® (ABIN3043447). Tested in IF, IHC, ICC, WB applications. This antibody reacts with Human, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human TCPTP recombinant protein (Position: M1-C330). Human TCPTP shares 91.4% and 92% amino acid (aa) sequence identity with mouse and rat TCPTP, respectively.
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亚型
- IgG
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anti-Protein tyrosine Phosphatase, Non-Receptor Type 2 (PTPN2) (AA 1-353) antibody
PTPN2 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Protein tyrosine Phosphatase, Non-Receptor Type 2 (PTPN2) (AA 1-257) antibodyPTPN2 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Protein tyrosine Phosphatase, Non-Receptor Type 2 (PTPN2) (AA 1-387) antibodyPTPN2 适用: 人 WB, IP, IF 宿主: 兔 Polyclonal unconjugated
anti-Protein tyrosine Phosphatase, Non-Receptor Type 2 (PTPN2) antibodyPTPN2 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Protein tyrosine Phosphatase, Non-Receptor Type 2 (PTPN2) (C-Term) antibodyPTPN2 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Protein tyrosine Phosphatase, Non-Receptor Type 2 (PTPN2) (AA 201-250) antibodyPTPN2 适用: 人, 小鼠, 大鼠, 豚鼠, 马, 兔, 犬, Cow, 斑马鱼, 小鸡, 猴, 非洲爪蟾 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Protein tyrosine Phosphatase, Non-Receptor Type 2 (PTPN2) (AA 329-358), (C-Term) antibodyPTPN2 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB33304 unconjugated
anti-Protein tyrosine Phosphatase, Non-Receptor Type 2 (PTPN2) antibodyPTPN2 适用: 人, 小鼠, 大鼠 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-Protein tyrosine Phosphatase, Non-Receptor Type 2 (PTPN2) (AA 1-387) antibodyPTPN2 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Protein tyrosine Phosphatase, Non-Receptor Type 2 (PTPN2) (AA 23-72) antibodyPTPN2 适用: 人, 小鼠, 大鼠, 豚鼠, 马, 兔, Cow, 斑马鱼, 小鸡, 猴 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.1-0.5 μg/mL, Human
Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human, Rat
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
1. "Entrez Gene: PTPN2 protein tyrosine phosphatase, non-receptor type 2". 2. Brown-Shimer S, Johnson KA, Lawrence JB, Johnson C, Bruskin A, Green NR, Hill DE (Aug 1990). "Molecular cloning and chromosome mapping of the human gene encoding protein phosphotyrosyl phosphatase 1B". Proc Natl Acad Sci U S A 87 (13): 5148-52. -
说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- PTPN2 (Protein tyrosine Phosphatase, Non-Receptor Type 2 (PTPN2))
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别名
- PTPN2
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背景
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Synonyms: Tyrosine-protein phosphatase non-receptor type 2,3.1.3.48,T-cell protein-tyrosine phosphatase,TCPTP,PTPN2,PTPT,
Tissue Specificity: Ubiquitously expressed. Isoform 2 is probably the major isoform. Isoform 1 is expressed in T-cells and in placenta. .
Background: TCPTP is also called as PTPN2. The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. Members of the PTP family share a highly conserved catalytic motif, which is essential for the catalytic activity. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. Epidermal growth factor receptor and the adaptor protein Shc were reported to be substrates of this PTP, which suggested the roles in growth factor mediated cell signaling. Multiple alternatively spliced transcript variants encoding different isoforms have been found. Two highly related but distinctly processed pseudogenes that localize to chromosomes 1 and 13, respectively, have been reported.
Sequence Similarities: Belongs to the protein-tyrosine phosphatase family. Non-receptor class 1 subfamily.
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分子量
- 48 kDa
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基因ID
- 5771
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UniProt
- P17706
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途径
- EGFR Signaling Pathway, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process, Platelet-derived growth Factor Receptor Signaling
抗原
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