Src 抗体 (AA 2-368)
(1 reference)-
- 抗原 See all Src 抗体
- Src (Proto-oncogene tyrosine-protein kinase Src (Src))
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抗原表位
- AA 2-368
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Src antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 原理
- Rabbit IgG polyclonal antibody for Proto-oncogene tyrosine-protein kinase Src(SRC) detection. Tested with WB, IHC-P in Human.
- 交叉反应 （详细）
- No cross reactivity with other proteins.
- 产品特性
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Rabbit IgG polyclonal antibody for Proto-oncogene tyrosine-protein kinase Src(SRC) detection. Tested with WB, IHC-P in Human.
Gene Name: SRC proto-oncogene, non-receptor tyrosine kinase
Protein Name: Proto-oncogene tyrosine-protein kinase Src - 纯化方法
- Immunogen affinity purified.
- 免疫原
- E.coli-derived human Src recombinant protein (Position: G2-D368). Human Src shares 97% and 99% amino acid (aa) sequence identity with mouse and rat Src, respectively.
- 亚型
- IgG
- Top Product
- Discover our top product Src Primary Antibody
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anti-Proto-oncogene tyrosine-protein kinase Src (Src) antibody
Src 适用: 人 WB, ELISA, IHC, FACS 宿主: 小鼠 Monoclonal 1F11 unconjugated
anti-Proto-oncogene tyrosine-protein kinase Src (Src) (pTyr530) antibodySrc 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Proto-oncogene tyrosine-protein kinase Src (Src) (AA 1-80) antibodySrc 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Proto-oncogene tyrosine-protein kinase Src (Src) antibodySrc 适用: 人, 小鼠 WB, IF 宿主: 小鼠 Monoclonal 17AT28 unconjugated
anti-Proto-oncogene tyrosine-protein kinase Src (Src) (AA 24-52), (N-Term) antibodySrc 适用: 人 WB, IF, IHC (p), FACS 宿主: 兔 Polyclonal RB41141 unconjugated
anti-Proto-oncogene tyrosine-protein kinase Src (Src) antibodyKO Validated Src 适用: 人 WB, IF, IP 宿主: 兔 Monoclonal unconjugated
anti-Proto-oncogene tyrosine-protein kinase Src (Src) (AA 397-424) antibodySrc 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Proto-oncogene tyrosine-protein kinase Src (Src) (AA 24-52) antibodySrc 适用: 人 WB, ELISA, IHC, IF, FACS 宿主: 兔 Polyclonal unconjugated
anti-Proto-oncogene tyrosine-protein kinase Src (Src) (pTyr529) antibodySrc 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Proto-oncogene tyrosine-protein kinase Src (Src) antibodySrc 适用: 人, 小鼠, 大鼠 IHC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, The detection limit for Src is approximately 0.25 ng/lane under reducing conditions.
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Mouse, Rat, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users. - 说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- 浓度
- 500 μg/mL
- 缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
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At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
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: "Slit2/Robo1 signaling promotes intestinal tumorigenesis through Src-mediated activation of the Wnt/?-catenin pathway." in: Oncotarget, Vol. 6, Issue 5, pp. 3123-35, (2015) (PubMed).
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: "Slit2/Robo1 signaling promotes intestinal tumorigenesis through Src-mediated activation of the Wnt/?-catenin pathway." in: Oncotarget, Vol. 6, Issue 5, pp. 3123-35, (2015) (PubMed).
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- 抗原
- Src (Proto-oncogene tyrosine-protein kinase Src (Src))
- 别名
- SRC (Src 产品)
- 别名
- AW259666 antibody, pp60c-src antibody, C-src1 antibody, CG7524 antibody, D-Src64B antibody, D-src antibody, DSRC64 antibody, DSrc antibody, DSrc64 antibody, DSrc64B antibody, Dm SRC1 antibody, DmHD-358 antibody, Dmel\CG7524 antibody, Dsrc antibody, Dsrc64 antibody, Dsrc64B antibody, HD-358 antibody, MRE5 antibody, SRC 64B antibody, Src antibody, Src1 antibody, Src64 antibody, c-src antibody, dSrc antibody, dsrc antibody, src antibody, src1 antibody, src64 antibody, src64B antibody, src64b antibody, ASV antibody, SRC1 antibody, c-SRC antibody, p60-Src antibody, c-Src antibody, PP60C-SCR antibody, SDR antibody, SRC proto-oncogene, non-receptor tyrosine kinase antibody, uncharacterized LOC5574802 antibody, proto-oncogene tyrosine-protein kinase src antibody, Rous sarcoma oncogene antibody, Src oncogene at 64B antibody, SRC antibody, LOC5574802 antibody, CpipJ_CPIJ010659 antibody, Src antibody, Src64B antibody
- 物质类
- Viral Protein
- 背景
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Sarcoma (Scr) is a proto-oncogenic tyrosine kinase originally discovered by J. Michael Bishop and Harold E. Varmus. belongs to a family of non-receptor tyrosine kinases called Src family kinases. The human SRC protooncogene was assigned to chromosome 20. Its gene is mapped to 20q12-q13. The discovery of Src family proteins has been instrumental to the modern understanding of cancer as a disease where normally healthy cellular signalling has gone awry. This proto-oncogene may play a role in the regulation of embryonic development and cell growth.
Synonyms: ASV antibody|Avian sarcoma virus antibody|c SRC antibody|CDNA FLJ14219 fis clone NT2RP3003800 highly similar to Rattus norvegicus tyrosine protein kinase pp60 c src mRNA antibody|cSrc antibody|EC 2.7.10.2 antibody|Neuronal CSRC tyrosine specific protein kinase antibody|Neuronal SRC antibody|Oncogene SRC antibody|OTTHUMP00000030931 antibody|OTTHUMP00000174476 antibody|OTTHUMP00000174477 antibody|p60 Src antibody|p60-Src antibody|p60Src antibody|pp60c src antibody|pp60c-src antibody|pp60csrc antibody|Proto oncogene tyrosine protein kinase Src antibody|Proto-oncogene c-Src antibody|Proto-oncogene tyrosine-protein kinase Src antibody|Protooncogene SRC antibody|protooncogene SRC Rous sarcoma antibody|Src antibody|SRC Oncogene antibody|SRC_HUMAN antibody|SRC1 antibody|Tyrosine kinase pp60c src antibody|Tyrosine protein kinase SRC 1 antibody|Tyrosine protein kinase SRC1 antibody|v src avian sarcoma (Schmidt Ruppin A2) viral oncogene homolog antibody|V src sarcoma (Schmidt Ruppin A 2) viral oncogene homolog (avian) antibody|v src sarcoma (Schmidt Ruppin A 2) viral oncogene homolog avian antibody|vsrc avian sarcoma (Schmidt Ruppin A2) viral oncogene homolog antibody - 基因ID
- 6714
- UniProt
- P12931
- 途径
- JAK/STAT Signaling, Neurotrophin Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Cellular Response to Molecule of Bacterial Origin, Cell-Cell Junction Organization, Regulation of Carbohydrate Metabolic Process, Autophagy, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, Smooth Muscle Cell Migration, Negative Regulation of intrinsic apoptotic Signaling, Platelet-derived growth Factor Receptor Signaling, Thromboxane A2 Receptor Signaling, Signaling of Hepatocyte Growth Factor Receptor, VEGF Signaling
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