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SHBG 抗体 (AA 30-210)

This anti-SHBG antibody is a 兔多克隆 antibody detecting SHBG in WB. Suitable for 人.

Anti- SHBG Picoband antibody, Western blotting All lanes: Anti SHBG at 0. (SHBG 抗体 (AA 30-210))

1 image

产品编号 ABIN3043434

发货至: 中国

Quick Overview for SHBG 抗体 (AA 30-210) (ABIN3043434)

抗原

See all SHBG 抗体

SHBG (Sex Hormone Binding Globulin (SHBG))

适用

79
51
47
17
2
1
1
1

人

宿主

兔

克隆类型

多克隆

标记

68
16
12
6
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1

This SHBG antibody is un-conjugated

应用范围

113
53
44
36
31
26
26
23
14
11
6
6
4
3
2
2
1
1
1

Western Blotting (WB)

Discover our top product SHBG Primary Antibody

抗原表位
16

15

9

9

8

7

6

5

3

3

2

2

1

1

1

1

1

1

1

1
AA 30-210

原理

Anti-Sex Hormone Binding Globulin/SHBG Antibody Picoband®

交叉反应（详细）

No cross-reactivity with other proteins

产品特性

Anti-Sex Hormone Binding Globulin/SHBG Antibody Picoband® (ABIN3043434). Tested in WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

纯化方法

Immunogen affinity purified.

免疫原

E.coli-derived human SHBG recombinant protein (Position: L30-A210). Human SHBG shares 72% amino acid (aa) sequence identity with both mouse and rat SHBG.

亚型

IgG
anti-Sex Hormone Binding Globulin (SHBG) (AA 224-388) antibody
SHBG 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C6 unconjugated

anti-Sex Hormone Binding Globulin (SHBG) (AA 51-150) antibody
SHBG 适用: 大鼠, 小鼠, Cow WB, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Sex Hormone Binding Globulin (SHBG) (AA 301-402) antibody
SHBG 适用: 大鼠, 小鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Sex Hormone Binding Globulin (SHBG) (AA 222-358) antibody
SHBG 适用: 大鼠 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C4 unconjugated

anti-Sex Hormone Binding Globulin (SHBG) (AA 41-140) antibody
SHBG 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated

anti-Sex Hormone Binding Globulin (SHBG) (AA 41-140) antibody
SHBG 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 5E6 unconjugated

anti-Sex Hormone Binding Globulin (SHBG) (AA 44-222) antibody
SHBG 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Sex Hormone Binding Globulin (SHBG) antibody
SHBG 适用: 人 IHC, ELISA, Coat, StM 宿主: 小鼠 Monoclonal SHBG-245 unconjugated

anti-Sex Hormone Binding Globulin (SHBG) (AA 30-170) antibody
SHBG 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Sex Hormone Binding Globulin (SHBG) (AA 51-218) antibody
SHBG 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

应用备注

Western blot, 0.1-0.5 μg/mL, Human
1. Hammond GL (2011). "Diverse Roles for Sex Hormone-Binding Globulin in Reproduction". Biology of Reproduction 85(3): 431-441. 2. Selva, D. M., Hogeveen, K. N., Innis, S. M., Hammond, G. L. Monosaccharide-induced lipogenesis regulates the human hepatic sex hormone-binding globulin gene. J. Clin. Invest. 117: 3979-3987, 2007. 3. Simó R, Barbosa-Desongles A, Hernandez C, Selva DM (November 2012). "IL1β down-regulation of sex hormone-binding globulin production by decreasing HNF-4α via MEK-1/2 and JNK MAPK pathways". Mol. Endocrinol. 26 (11): 1917-27.

说明

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

限制

仅限研究用
状态

Lyophilized

溶解方式

Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

浓度

500 μg/mL

缓冲液

Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freezing and thawing.

储存条件

4 °C,-20 °C

储存方法

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
抗原

SHBG (Sex Hormone Binding Globulin (SHBG))

别名

SHBG

背景

Synonyms: Sex hormone-binding globulin,SHBG,Sex steroid-binding protein,SBP,Testis-specific androgen-binding protein,ABP,Testosterone-estradiol-binding globulin,TeBG,Testosterone-estrogen-binding globulin,SHBG,
Tissue Specificity: Isoform 1 and isoform 2 are present in liver and testis.
Background: Sex hormone-binding globulin (SHBG) is a glycoprotein that binds to the sex hormones,androgen and estrogen. SHBG is produced mostly by the liver and is released into the bloodstream. Other sites that produce SHBG include the brain, uterus, testes, and placenta. SHBG has both enhancing and inhibiting hormonal influences. It decreases with high levels of insulin, growth hormone, insulin-like growth factor 1 (IGF-1), androgens, prolactin and transcortin. High estrogen, andthyroxine cause it to increase. It has been found that the monosaccharides glucose and fructose reduced human SHBG production by hepatocytes, irrespective of the presence of insulin, by downregulation of hepatocyte nuclear factor-4A and replacement of HNF4A by COUP-TFI at a cis-element within the human SHBG promoter, coincident with repression of its transcriptional activity.
Sequence Similarities: Contains 2 laminin G-like domains.

分子量

70 kDa

基因ID

6462

UniProt

P04278

途径

Hormone Transport

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