SHBG 抗体 (AA 30-210)
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北京 101111
Quick Overview for SHBG 抗体 (AA 30-210) (ABIN3043434)
抗原
See all SHBG 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 30-210
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原理
- Anti-Sex Hormone Binding Globulin/SHBG Antibody
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交叉反应 （详细）
- No cross-reactivity with other proteins
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产品特性
- Anti-Sex Hormone Binding Globulin/SHBG Antibody (ABIN3043434). Tested in WB applications. This antibody reacts with Human. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human SHBG recombinant protein (Position: L30-A210). Human SHBG shares 72% amino acid (aa) sequence identity with both mouse and rat SHBG.
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亚型
- IgG
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anti-Sex Hormone Binding Globulin (SHBG) (AA 224-388) antibody
SHBG 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C6 unconjugated
anti-Sex Hormone Binding Globulin (SHBG) (AA 51-150) antibodySHBG 适用: 大鼠, 小鼠, Cow WB, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Sex Hormone Binding Globulin (SHBG) (AA 301-402) antibodySHBG 适用: 大鼠, 小鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Sex Hormone Binding Globulin (SHBG) (AA 222-358) antibodySHBG 适用: 大鼠 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C4 unconjugated
anti-Sex Hormone Binding Globulin (SHBG) (AA 41-140) antibodySHBG 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Sex Hormone Binding Globulin (SHBG) (AA 41-140) antibodySHBG 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 5E6 unconjugated
anti-Sex Hormone Binding Globulin (SHBG) (AA 44-222) antibodySHBG 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Sex Hormone Binding Globulin (SHBG) (AA 30-170) antibodySHBG 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Sex Hormone Binding Globulin (SHBG) antibodySHBG 适用: 人 IHC, ELISA, Coat, StM 宿主: 小鼠 Monoclonal SHBG-245 unconjugated
anti-Sex Hormone Binding Globulin (SHBG) (AA 51-218) antibodySHBG 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.1-0.5 μg/mL, Human
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说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- SHBG (Sex Hormone Binding Globulin (SHBG))
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别名
- SHBG
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背景
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Synonyms: Sex hormone-binding globulin,SHBG,Sex steroid-binding protein,SBP,Testis-specific androgen-binding protein,ABP,Testosterone-estradiol-binding globulin,TeBG,Testosterone-estrogen-binding globulin,SHBG,
Tissue Specificity: Isoform 1 and isoform 2 are present in liver and testis.
Background: Sex hormone-binding globulin (SHBG) is a glycoprotein that binds to the sex hormones,androgen and estrogen. SHBG is produced mostly by the liver and is released into the bloodstream. Other sites that produce SHBG include the brain, uterus, testes, and placenta. SHBG has both enhancing and inhibiting hormonal influences. It decreases with high levels of insulin, growth hormone, insulin-like growth factor 1 (IGF-1), androgens, prolactin and transcortin. High estrogen, andthyroxine cause it to increase. It has been found that the monosaccharides glucose and fructose reduced human SHBG production by hepatocytes, irrespective of the presence of insulin, by downregulation of hepatocyte nuclear factor-4A and replacement of HNF4A by COUP-TFI at a cis-element within the human SHBG promoter, coincident with repression of its transcriptional activity.
Sequence Similarities: Contains 2 laminin G-like domains.
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分子量
- 70 kDa
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基因ID
- 6462
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UniProt
- P04278
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途径
- Hormone Transport
抗原
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