MLH1 抗体 (C-Term)
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Quick Overview for MLH1 抗体 (C-Term) (ABIN3043404)
抗原
See all MLH1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 722-756, C-Term
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原理
- Anti-MLH1 Antibody
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序列
- KALRSHILPP KHFTEDGNIL QLANLPDLYK VFERC
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-MLH1 Antibody (ABIN3043404). Tested in WB applications. This antibody reacts with Human. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the C-terminus of human MLH1, different from the related mouse sequence by three amino acids, and from the related rat sequence by four amino acids.
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亚型
- IgG
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anti-MutL Homolog 1 (MLH1) (AA 1-756) antibody
MLH1 适用: 人 WB, ELISA, IF, IHC (p), PLA 宿主: 小鼠 Monoclonal M1 unconjugated
anti-MutL Homolog 1 (MLH1) (AA 381-483) antibodyMLH1 适用: 人 ELISA, ICC, FACS 宿主: 小鼠 Monoclonal 8C12B7 unconjugated
anti-MutL Homolog 1 (MLH1) (AA 381-483) antibodyMLH1 适用: 人 WB, ELISA, IHC, FACS 宿主: 小鼠 Monoclonal 7A7C8 unconjugated
anti-MutL Homolog 1 (MLH1) (AA 350-519) antibodyMLH1 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-MutL Homolog 1 (MLH1) (AA 381-483) antibodyMLH1 适用: 人, 猴 WB, ELISA, IHC, ICC 宿主: 小鼠 Monoclonal 4C9C7 unconjugated
anti-MutL Homolog 1 (MLH1) (Internal Region) antibodyMLH1 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-MutL Homolog 1 (MLH1) antibodyMLH1 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-MutL Homolog 1 (MLH1) (AA 501-600) antibodyMLH1 适用: 人 ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-MutL Homolog 1 (MLH1) antibodyMLH1 适用: 人 WB, FACS 宿主: 小鼠 Monoclonal 24GB13305 unconjugated
anti-MutL Homolog 1 (MLH1) (Internal Region) antibodyMLH1 适用: 人, 小鼠, 大鼠 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.1-0.5 μg/mL, Human
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说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- MLH1 (MutL Homolog 1 (MLH1))
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别名
- MLH1
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背景
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Synonyms: DNA mismatch repair protein Mlh1,MutL protein homolog 1,MLH1,COCA2,
Tissue Specificity: Colon, lymphocytes, breast, lung, spleen, testis, prostate, thyroid, gall bladder and heart.
Background: MutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli) is a protein that in humans is encoded by the MLH1 gene located on Chromosome 3. This gene was identified as a locus frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). It is a human homolog of the E. coli DNA mismatch repair gene mutL, consistent with the characteristic alterations in microsatellite sequences (RER+phenotype) found in HNPCC. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described, but their full-length natures have not been determined.
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分子量
- 85 kDa
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基因ID
- 4292
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UniProt
- P40692
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途径
- DNA Damage Repair, Production of Molecular Mediator of Immune Response
抗原
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