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MLH1 抗体 (C-Term)

This anti-MLH1 antibody is a 兔多克隆 antibody detecting MLH1 in WB. Suitable for 人.

Western Blotting (WB) image for anti-MutL Homolog 1 (MLH1) (AA 722-756), (C-Term) antibody (ABIN3043404) (MLH1 抗体 (C-Term))

1 image

产品编号 ABIN3043404

发货至: 中国

Quick Overview for MLH1 抗体 (C-Term) (ABIN3043404)

抗原

See all MLH1 抗体

MLH1 (MutL Homolog 1 (MLH1))

适用

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人

宿主

兔

克隆类型

多克隆

标记

61
5
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1
1
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This MLH1 antibody is un-conjugated

应用范围

52
34
21
15
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3
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Western Blotting (WB)

Discover our top product MLH1 Primary Antibody

抗原表位
15

10

7

4

4

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2

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AA 722-756, C-Term

原理

Anti-MLH1 Antibody Picoband®

序列

KALRSHILPP KHFTEDGNIL QLANLPDLYK VFERC

交叉反应（详细）

No cross-reactivity with other proteins.

产品特性

Anti-MLH1 Antibody Picoband® (ABIN3043404). Tested in WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

纯化方法

Immunogen affinity purified.

免疫原

A synthetic peptide corresponding to a sequence at the C-terminus of human MLH1, different from the related mouse sequence by three amino acids, and from the related rat sequence by four amino acids.

亚型

IgG
anti-MutL Homolog 1 (MLH1) (AA 1-756) antibody
MLH1 适用: 人 WB, ELISA, IF, IHC (p), PLA 宿主: 小鼠 Monoclonal M1 unconjugated

anti-MutL Homolog 1 (MLH1) (AA 381-483) antibody
MLH1 适用: 人 WB, ELISA, IHC, FACS 宿主: 小鼠 Monoclonal 7A7C8 unconjugated

anti-MutL Homolog 1 (MLH1) (AA 381-483) antibody
MLH1 适用: 人 ELISA, ICC, FACS 宿主: 小鼠 Monoclonal 8C12B7 unconjugated

anti-MutL Homolog 1 (MLH1) (AA 350-519) antibody
MLH1 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-MutL Homolog 1 (MLH1) (AA 381-483) antibody
MLH1 适用: 人, 猴 WB, ELISA, IHC, ICC 宿主: 小鼠 Monoclonal 4C9C7 unconjugated

anti-MutL Homolog 1 (MLH1) (Internal Region) antibody
MLH1 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-MutL Homolog 1 (MLH1) antibody
MLH1 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-MutL Homolog 1 (MLH1) (AA 501-600) antibody
MLH1 适用: 人 ELISA, IHC (p), IF (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-MutL Homolog 1 (MLH1) (Internal Region) antibody
MLH1 适用: 人, 小鼠, 大鼠 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated

anti-MutL Homolog 1 (MLH1) (AA 373-735) antibody
MLH1 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal unconjugated

应用备注

Western blot, 0.1-0.5 μg/mL, Human
1. Tawfik HM, El-Maqsoud NM, Hak BH, El-Sherbiny YM (2011). "Head and neck squamous cell carcinoma: mismatch repair immunohistochemistry and promoter hypermethylation of hMLH1 gene". Am J Otolaryngol 32 (6): 528-36. 2. "Entrez Gene: MLH1 mutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli)".

说明

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

限制

仅限研究用
状态

Lyophilized

溶解方式

Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

浓度

500 μg/mL

缓冲液

Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freezing and thawing.

储存条件

4 °C,-20 °C

储存方法

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
抗原

MLH1 (MutL Homolog 1 (MLH1))

别名

MLH1

背景

Synonyms: DNA mismatch repair protein Mlh1,MutL protein homolog 1,MLH1,COCA2,
Tissue Specificity: Colon, lymphocytes, breast, lung, spleen, testis, prostate, thyroid, gall bladder and heart.
Background: MutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli) is a protein that in humans is encoded by the MLH1 gene located on Chromosome 3. This gene was identified as a locus frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). It is a human homolog of the E. coli DNA mismatch repair gene mutL, consistent with the characteristic alterations in microsatellite sequences (RER+phenotype) found in HNPCC. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described, but their full-length natures have not been determined.

分子量

85 kDa

基因ID

4292

UniProt

P40692

途径

DNA Damage Repair, Production of Molecular Mediator of Immune Response

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