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Galectin 3 抗体 (AA 153-264)

This anti-Galectin 3 antibody is a 兔 多克隆 antibody detecting Galectin 3 in WB 和 IHC. Suitable for 小鼠 和 大鼠.
产品编号 ABIN3043400
发货至: 中国

Quick Overview for Galectin 3 抗体 (AA 153-264) (ABIN3043400)

抗原

See all Galectin 3 (LGALS3) 抗体
Galectin 3 (LGALS3)

适用

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小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This Galectin 3 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

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    AA 153-264

    原理

    Anti-Galectin 3/LGALS3 Antibody Picoband®

    交叉反应 (详细)

    No cross-reactivity with other proteins

    产品特性

    Anti-Galectin 3/LGALS3 Antibody Picoband® (ABIN3043400). Tested in IHC, WB applications. This antibody reacts with Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived mouse Galectin 3 recombinant protein (Position: K153-I264). Mouse Galectin 3 shares 88% and 91% amino acid (aa) sequence identity with human and rat Galectin 3, respectively.

    亚型

    IgG
  • 应用备注

    Western blot, 0.1-0.5 μg/mL, Mouse, Rat
    Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Mouse, Rat
    1. Dumic J, Dabelic S, Flögel M. (2006). "Galectin-3: an open-ended story.". BBA General Subjects 1760(4): 616-635. 2. Liu F, Patterson RJ, Wang JL. (2002). "Intracellular function of galectins.". BBA General Subjects 1572 (2-3): 263-273. 3. Cooper D. (2002). "Galectinomics: finding themes in complexity.". BBA General Subjects 1572 (2-3): 209-231. 4. Raimond J, Zimonjic DB, Mignon C, et al. (1997). "Mapping of the galectin-3 gene (LGALS3) to human chromosome 14 at region 14q21-22.". Mamm. Genome 8 (9): 706-707.

    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • 抗原

    Galectin 3 (LGALS3)

    别名

    LGALS3

    背景

    Synonyms: Galectin-3;Gal-3;35 kDa lectin;Carbohydrate-binding protein 35;CBP 35;Galactose-specific lectin 3;IgE-binding protein;L-34 galactoside-binding lectin;Laminin-binding protein;Lectin L-29;Mac-2 antigen;Lgals3;

    Tissue Specificity: The highest levels are found in activated macrophages.

    Background: Galectin-3 (GAL3), also known as LGALS3, MAC2 or GALBP, is a member of the lectin family, of which 14 mammalian galectins have been identified. Galectin-3 is encoded by a single gene, it located on chromosome 14, locus q21–q22. It is expressed in the nucleus, cytoplasm,mitochondrion, cell surface, and extracellular space. Studies have also shown that the expression of galectin-3 is implicated in a variety of processes associated with heart failure, including myofibroblast proliferation, fibrogenesis, tissue repair, inflammation, and Ventricular remodeling. Galectin-3 is expressed in various tissues and organs, but is significantly absent in normal hepatocytes.

    Sequence Similarities: Contains 3 cystatin kininogen-type domains.

    分子量

    29 kDa

    基因ID

    16854

    UniProt

    P16110

    途径

    RTK signaling
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