Galectin 3 抗体 (AA 139-250)
Quick Overview for Galectin 3 抗体 (AA 139-250) (ABIN3043399)
抗原
See all Galectin 3 (LGALS3) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 139-250
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原理
- Anti-Galectin 3/LGALS3 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins
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产品特性
- Anti-Galectin 3/LGALS3 Antibody Picoband® (ABIN3043399). Tested in Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human Galectin 3 recombinant protein (Position: K139-I250). Human Galectin 3 shares 88% and 84% amino acid (aa) sequences identity with mouse and rat Galectin 3, respectively.
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亚型
- IgG
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anti-Galectin 3 (LGALS3) (AA 1-250) antibody
LGALS3 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Galectin 3 (LGALS3) (AA 1-250) antibodyLGALS3 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Galectin 3 (LGALS3) antibodyLGALS3 适用: 人 WB, IHC, IP 宿主: 兔 Monoclonal unconjugated
anti-Galectin 3 (LGALS3) antibodyLGALS3 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Galectin 3 (LGALS3) (AA 1-250) antibodyLGALS3 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 3G8 unconjugated
anti-Galectin 3 (LGALS3) (AA 151-250) antibodyLGALS3 适用: 人, 小鼠 ELISA, IHC (p), FACS, IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Galectin 3 (LGALS3) (AA 1-262) antibodyLGALS3 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Galectin 3 (LGALS3) antibodyLGALS3 适用: 人 WB, IHC, ELISA, IF, IP 宿主: 兔 Monoclonal 4E1 unconjugated Recombinant Antibody
anti-Galectin 3 (LGALS3) (AA 1-250) antibodyLGALS3 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Galectin 3 (LGALS3) (AA 2-250) antibodyLGALS3 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.1-0.5 μg/mL, Human
Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human1. Dumic J, Dabelic S, Flögel M. (2006). "Galectin-3: an open-ended story.". BBA General Subjects 1760(4): 616-635. 2. Liu F, Patterson RJ, Wang JL. (2002). "Intracellular function of galectins.". BBA General Subjects 1572 (2-3): 263-273. 3. Cooper D. (2002). "Galectinomics: finding themes in complexity.". BBA General Subjects 1572 (2-3): 209-231. 4. Raimond J, Zimonjic DB, Mignon C, et al. (1997). "Mapping of the galectin-3 gene (LGALS3) to human chromosome 14 at region 14q21-22.". Mamm. Genome 8 (9): 706-707. -
说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- Galectin 3 (LGALS3)
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别名
- LGALS3
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背景
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Synonyms: Galectin-3;Gal-3;35 kDa lectin;Carbohydrate-binding protein 35;CBP 35;Galactose-specific lectin 3;Galactoside-binding protein;GALBP;IgE-binding protein;L-31;Laminin-binding protein;Lectin L-29;Mac-2 antigen;LGALS3;MAC2;
Tissue Specificity: A major expression is found in the colonic epithelium. It is also abundant in the activated macrophages. Expressed in fetal membranes. .
Background: Galectin-3 (GAL3), also known as LGALS3, MAC2 or GALBP, is a member of the lectin family, of which 14 mammalian galectins have been identified. Galectin-3 is encoded by a single gene, it located on chromosome 14, locus q21–q22. It is expressed in the nucleus, cytoplasm,mitochondrion, cell surface, and extracellular space. Studies have also shown that the expression of galectin-3 is implicated in a variety of processes associated with heart failure, including myofibroblast proliferation, fibrogenesis, tissue repair, inflammation, and Ventricular remodeling. Galectin-3 is expressed in various tissues and organs, but is significantly absent in normal hepatocytes.
Sequence Similarities: Contains 1 galectin domain.
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分子量
- 26 kDa
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基因ID
- 3958
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UniProt
- P17931
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途径
- RTK signaling
抗原
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