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CD63 抗体 (AA 97-238)

Cited in 2+ publications. The 兔 多克隆 anti-CD63 antibody (ABIN3043395) specifically detects CD63 in WB 和 IHC. The antibody is reactive with 人 samples.
产品编号 ABIN3043395
发货至: 中国
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Quick Overview for CD63 抗体 (AA 97-238) (ABIN3043395)

抗原

See all CD63 抗体
CD63

适用

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宿主

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克隆类型

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多克隆

标记

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This CD63 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

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    AA 97-238

    原理

    Anti-CD63 Antibody

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins

    预测反应

    Human CD63 shares 74%,73% amino acid (aa) sequence identity with mouse,rat CD63,respectively.

    产品特性

    Anti-CD63 Antibody. Tested in IHC, WB applications. This antibody reacts with Human.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human CD63 recombinant protein (Position: E97-M238). Human CD63 shares 74% and 73% amino acid (aa) sequence identity with mouse and rat CD63, respectively.

    亚型

    IgG
  • 应用备注

    Western blot, 0.1-0.5 μg/mL, Human Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human

    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • Ren, Wang, Yuan, Wang: "Dendritic cells loaded with HeLa-derived exosomes simulate an antitumor immune response." in: Oncology letters, Vol. 15, Issue 5, pp. 6636-6640, (2018) (PubMed).

    Du, Dong, Zhao, Fu, Wang, Chen, Ou, Li, Sun, Tang, Song: "Immunostimulatory and anti-neoplasm effects of a novel palindrome CpG oligodeoxynucleotide in mice." in: Acta pharmacologica Sinica, Vol. 33, Issue 8, pp. 1047-54, (2012) (PubMed).

  • 抗原

    CD63

    别名

    CD63

    背景

    Background: CD63 antigen is a protein that in humans is encoded by the CD63 gene. The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. It is mapped to 12q13.2. CD63 is mainly associated with membranes of intracellular vesicles, although cell surface expression may be induced. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins. It may function as a blood platelet activation marker. Deficiency of this protein is associated with Hermansky-Pudlak syndrome. Also this gene has been associated with tumor progression.

    Gene Full Name: CD63 Molecule

    分子量

    30-60 kDa

    基因ID

    967

    UniProt

    P08962
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