-
- 抗原 See all PD-L1 抗体
- PD-L1 (CD274 (PD-L1))
-
抗原表位
- AA 45-290
-
适用
- 人
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This PD-L1 antibody is un-conjugated
-
应用范围
- Western Blotting (WB)
- 原理
- Rabbit IgG polyclonal antibody for Programmed cell death 1 ligand 1(CD274) detection. Tested with WB in Human.
- 交叉反应 （详细）
- No cross reactivity with other proteins.
- 产品特性
-
Rabbit IgG polyclonal antibody for Programmed cell death 1 ligand 1(CD274) detection. Tested with WB in Human.
Gene Name: CD274 Molecule
Protein Name: Programmed cell death 1 ligand 1 - 纯化方法
- Immunogen affinity purified.
- 免疫原
- E.coli-derived human PD-L1 recombinant protein (Position: E45-T290). Human PD-L1 shares 69% amino acid (aa) sequence identity with mouse PD-L1.
- 亚型
- IgG
- Top Product
- Discover our top product PD-L1 Primary Antibody
-
anti-CD274 (PD-L1) (C-Term) antibody
Verified PD-L1 适用: 人 WB, FACS, ELISA, IF 宿主: 山羊 Polyclonal unconjugated
anti-CD274 (PD-L1) (AA 19-238) antibodyPD-L1 适用: 人 WB, FACS, IHC, ELISA, IF 宿主: 小鼠 Monoclonal 9B5F4 unconjugated
anti-CD274 (PD-L1) (AA 39-191) antibodyPD-L1 适用: 人, 小鼠 WB, FACS, IHC, ELISA, IF, Coat, StM 宿主: 小鼠 Monoclonal PDL1-2746 unconjugated
anti-CD274 (PD-L1) (AA 24-153) antibodyPD-L1 适用: 人 WB, FACS, IHC, ELISA, ICC, Neut 宿主: 小鼠 Monoclonal 6D9A2 unconjugated
anti-CD274 (PD-L1) (AA 48-290) antibodyPD-L1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-CD274 (PD-L1) (Extracellular Domain) antibodyPD-L1 适用: 人 IHC 宿主: 兔 Monoclonal unconjugated
anti-CD274 (PD-L1) (AA 34-241) antibodyPD-L1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-CD274 (PD-L1) (AA 19-238) antibodyPD-L1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-CD274 (PD-L1) antibodyKO Validated PD-L1 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated
anti-CD274 (PD-L1) (C-Term) antibodyKO Validated PD-L1 适用: 人 WB, FACS, ICC, IF, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
-
- 应用备注
-
WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, The detection limit for PD-L1 is approximately 0.25 ng/lane under reducing conditions.
Notes: Tested Species: Species with positive results.
Other applications have not been tested. Optimal dilutions should be determined by end users. - 说明
-
Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
- 限制
- 仅限研究用
-
- 状态
- Lyophilized
- 溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- 浓度
- 500 μg/mL
- 缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
-
At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
-
- 抗原
- PD-L1 (CD274 (PD-L1))
- 别名
- CD274 (PD-L1 产品)
- 别名
- B7-H antibody, B7H1 antibody, PD-L1 antibody, PDCD1L1 antibody, PDCD1LG1 antibody, PDL1 antibody, A530045L16Rik antibody, B7h1 antibody, Pdcd1l1 antibody, Pdcd1lg1 antibody, Pdl1 antibody, RGD1566211 antibody, CD274 molecule antibody, CD274 antigen antibody, programmed cell death 1 ligand 2 antibody, CD274 antibody, Cd274 antibody, PDCD1LG2 antibody
- 背景
-
Programmed death-ligand 1 (PD-L1) also known as CD274 or B7-H1 is a protein that in humans is encoded by the CD274 gene. It is mapped to 9p24.1. PD-L1 is a 40 kDa type 1 transmembrane protein that has been speculated to play a major role in suppressing the immune system during particular events such as pregnancy, tissue allografts, autoimmune disease and other disease states such as hepatitis. It has been concluded that upregulation of PD-L1 on tumor MDCs downregulates T-cell immunity and that PD-L1 blockade may represent an approach for cancer immunotherapy. PD-L1 can provide positive costimulatory signals for innate and adaptive immunity and for protection against intracellular bacterial infection. What's more, It has been found that PD1/PDL1 pathway may be a good target for restoring antitumor immunity in ovarian cancer.
Synonyms: B7 H antibody|B7 H1 antibody|B7 homolog 1 antibody|B7-H1 antibody|B7H antibody|B7H1 antibody|CD 274 antibody|CD274 antibody|Cd274 antibody|CD274 antigen antibody|CD274 Molecule antibody|MGC142294 antibody|MGC142296 antibody|OTTHUMP00000021029 antibody|PD L1 antibody|PD-L1 antibody|PD1L1_HUMAN antibody|PDCD1 ligand 1 antibody|PDCD1L1 antibody|PDCD1LG1 antibody|PDL 1 antibody|PDL1 antibody|Programmed cell death 1 ligand 1 antibody|Programmed death ligand 1 antibody|RGD1566211 antibody - 基因ID
- 29126
- 途径
- Cancer Immune Checkpoints
-
You are here:
