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PKC delta 抗体 (AA 1-160)

PKCd 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3043360
发货至: 中国
  • 抗原 See all PKC delta (PKCd) 抗体
    PKC delta (PKCd) (Protein Kinase C, delta (PKCd))
    抗原表位
    • 22
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    • 16
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    AA 1-160
    适用
    • 202
    • 152
    • 150
    • 8
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    宿主
    • 213
    • 9
    克隆类型
    • 202
    • 20
    多克隆
    标记
    • 91
    • 14
    • 12
    • 10
    • 9
    • 9
    • 9
    • 9
    • 9
    • 9
    • 7
    • 6
    • 6
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    This PKC delta antibody is un-conjugated
    应用范围
    • 157
    • 86
    • 81
    • 80
    • 49
    • 41
    • 36
    • 23
    • 20
    • 13
    • 5
    • 3
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    Western Blotting (WB)
    原理
    Rabbit IgG polyclonal antibody for Protein kinase C delta type(PRKCD) detection. Tested with WB in Human.
    交叉反应 (详细)
    No cross reactivity with other proteins.
    产品特性
    Rabbit IgG polyclonal antibody for Protein kinase C delta type(PRKCD) detection. Tested with WB in Human.
    Gene Name: protein kinase C, delta
    Protein Name: Protein kinase C delta type
    纯化方法
    Immunogen affinity purified.
    免疫原
    E.coli-derived human PKC delta recombinant protein (Position: M1-E160). Human PKC delta shares 95% and 93% amino acid (aa) sequence identity with mouse and rat PKC delta, respctively.
    亚型
    IgG
    Top Product
    Discover our top product PKCd Primary Antibody
  • 应用备注
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, The detection limit for PKC delta is approximately 0.25 ng/lane under reducing conditions.
    Notes: Tested Species: Species with positive results.
    Other applications have not been tested. Optimal dilutions should be determined by end users.
    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    浓度
    500 μg/mL
    缓冲液
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
  • Gan, Wang, Zhao, Wu, Yang, Peng: "5-(Bis(3-(2-hydroxyethyl)-1H-indol-2-yl)methyl)-2-hydroxybenzoic acid (BHIMHA): showing a strategy of designing drug to block lung metastasis of tumors." in: Drug design, development and therapy, Vol. 10, pp. 711-21, (2016) (PubMed).

  • 抗原
    PKC delta (PKCd) (Protein Kinase C, delta (PKCd))
    别名
    PRKCD (PKCd 产品)
    别名
    MAY1 antibody, PKCD antibody, nPKC-delta antibody, AI385711 antibody, D14Ertd420e antibody, PKC[d] antibody, PKCdelta antibody, Pkcd antibody, fb09d10 antibody, fv43b11 antibody, prkcd antibody, wu:fb09d10 antibody, wu:fv43b11 antibody, zgc:56558 antibody, PKC-delta antibody, may1 antibody, npkc-delta antibody, pkc-delta2 antibody, pkcd antibody, tpa-1 antibody, protein kinase C delta antibody, protein kinase C, delta antibody, protein kinase C, delta a antibody, protein kinase C delta L homeolog antibody, PRKCD antibody, Prkcd antibody, prkcda antibody, prkcd.L antibody, prkcd antibody
    背景
    Protein kinase C delta type, also called PKCD, is an enzyme that in humans is encoded by the PRKCD gene. The PRKCD gene encodes a member of the protein kinase C family, members of which are critical for regulation of cell survival, proliferation, and apoptosis. This gene is mapped to 3p21.1. Studies both in human and mice demonstrate that this kinase is involved inB cell signaling and in the regulation of growth, apoptosis, and differentiation of a variety of cell types. PRKCD is also regulated by phosphorylation on various tyrosine residues including Y311 (by SRC). It has been showed that PRKCD phosphorylates NLRC4 and that this phosphorylation is critical for inflammasome assembly. What's more, it is also a part of a noncanonical WNT signaling cascade.

    Synonyms: CVID9 antibody|D14Ertd420e antibody|Kinase PKC delta antibody|KPCD antibody|KPCD_HUMAN antibody|MAY 1 antibody|MAY1 antibody|MGC49908 antibody|nPKC delta antibody|nPKC-delta antibody|PCKd antibody|PKC d antibody|PKC delta antibody|PKCd antibody|PKCD antibody|PKCdelta antibody|PRKC D antibody|PRKC delta antibody|Prkcd antibody|Protein Kinase C delta antibody|Protein kinase C delta type antibody|Protein kinase C delta VIII antibody|Protein Kinase Cdelta antibody|Tyrosine protein kinase PRKCD antibody
    基因ID
    5580
    UniProt
    Q05655
    途径
    Interferon-gamma Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Thyroid Hormone Synthesis, Regulation of Actin Filament Polymerization, Carbohydrate Homeostasis, Myometrial Relaxation and Contraction, M Phase, G-protein mediated Events, Dicarboxylic Acid Transport, Positive Regulation of Response to DNA Damage Stimulus, Interaction of EGFR with phospholipase C-gamma, Thromboxane A2 Receptor Signaling, Lipid Metabolism
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