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PKC delta 抗体 (AA 1-160)

Name: PKC delta 抗体 (AA 1-160)
SKU: ABIN3043360
Availability: OutOfStock

This 兔多克隆 antibody specifically detects PKC delta in WB 和 IHC. It exhibits reactivity toward 人, 小鼠和大鼠.It has been mentioned in 1 publication

nti- PKC delta antibody, Western blotting All lanes: Anti PKC delta at 0. (PKC delta 抗体 (AA 1-160))

1 image

(1 reference)

产品编号 ABIN3043360

发货至: 中国

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Quick Overview for PKC delta 抗体 (AA 1-160) (ABIN3043360)

抗原

See all PKC delta (PKCd) 抗体

PKC delta (PKCd) (Protein Kinase C, delta (PKCd))

适用

人, 小鼠, 大鼠

宿主

兔

克隆类型

多克隆

标记

This PKC delta antibody is un-conjugated

应用范围

Western Blotting (WB), Immunohistochemistry (IHC)

Discover our top product PKCd Primary Antibody

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AA 1-160

原理

Anti-PKC delta/PRKCD Antibody

特异性

No cross reactivity with other proteins.

交叉反应（详细）

No cross-reactivity with other proteins

预测反应

Human PKC delta shares 95%,93% amino acid (aa) sequence identity with mouse,rat PKC delta,respctively.

产品特性

Anti-PKC delta/PRKCD Antibody. Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat.

纯化方法

Immunogen affinity purified.

免疫原

E.coli-derived human PKC delta recombinant protein (Position: M1-E160). Human PKC delta shares 95% and 93% amino acid (aa) sequence identity with mouse and rat PKC delta, respctively.

亚型

IgG
anti-Protein Kinase C, delta (PKCd) antibody
KD Validated PKCd 适用: 小鼠 WB, IF (p), FACS 宿主: 兔 Monoclonal 24GB4485 unconjugated Recombinant Antibody

anti-Protein Kinase C, delta (PKCd) (AA 477-676) antibody
PKCd 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Protein Kinase C, delta (PKCd) (AA 4-676) antibody
PKCd 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, FACS, ICC 宿主: 兔 Polyclonal unconjugated

anti-Protein Kinase C, delta (PKCd) (AA 577-676) antibody
PKCd 适用: 人 WB, ELISA, RNAi 宿主: 小鼠 Monoclonal 6A2 unconjugated

anti-Protein Kinase C, delta (PKCd) (AA 577-676) antibody
PKCd 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 2E12 unconjugated

anti-Protein Kinase C, delta (PKCd) (pTyr313) antibody
PKCd 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Protein Kinase C, delta (PKCd) (C-Term) antibody
PKCd 适用: 人, 小鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Protein Kinase C, delta (PKCd) antibody
KD Validated PKCd 适用: 人 WB, FACS 宿主: 兔 Monoclonal 23GB2410 unconjugated Recombinant Antibody

anti-Protein Kinase C, delta (PKCd) (pSer645) antibody
PKCd 适用: 人, 小鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Protein Kinase C, delta (PKCd) (pTyr64) antibody
PKCd 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

应用备注

Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human

说明

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

限制

仅限研究用
状态

Lyophilized

溶解方式

Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

浓度

500 μg/mL

缓冲液

Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

注意事项

Avoid repeated freezing and thawing.

储存条件

4 °C,-20 °C

储存方法

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

有效期

12 months
Gan, Wang, Zhao, Wu, Yang, Peng: "5-(Bis(3-(2-hydroxyethyl)-1H-indol-2-yl)methyl)-2-hydroxybenzoic acid (BHIMHA): showing a strategy of designing drug to block lung metastasis of tumors." in: Drug design, development and therapy, Vol. 10, pp. 711-21, (2016) (PubMed).
抗原

PKC delta (PKCd) (Protein Kinase C, delta (PKCd))

别名

PRKCD

背景

Background: Protein kinase C delta type, also called PKCD, is an enzyme that in humans is encoded by the PRKCD gene. The PRKCD gene encodes a member of the protein kinase C family, members of which are critical for regulation of cell survival, proliferation, and apoptosis. This gene is mapped to 3p21.1. Studies both in human and mice demonstrate that this kinase is involved inB cell signaling and in the regulation of growth, apoptosis, and differentiation of a variety of cell types. PRKCD is also regulated by phosphorylation on various tyrosine residues including Y311 (by SRC). It has been showed that PRKCD phosphorylates NLRC4 and that this phosphorylation is critical for inflammasome assembly. What's more, it is also a part of a noncanonical WNT signaling cascade.
Gene Full Name: protein kinase C delta
Sequence Similarities: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.

分子量

78 kDa

基因ID

5580

UniProt

Q05655

途径

Interferon-gamma Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Thyroid Hormone Synthesis, Regulation of Actin Filament Polymerization, Carbohydrate Homeostasis, Myometrial Relaxation and Contraction, M Phase, G-protein mediated Events, Dicarboxylic Acid Transport, Positive Regulation of Response to DNA Damage Stimulus, Interaction of EGFR with phospholipase C-gamma, Thromboxane A2 Receptor Signaling, Lipid Metabolism