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PLK1 抗体 (AA 86-430)

PLK1 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3043354
发货至: 中国
  • 抗原 See all PLK1 抗体
    PLK1 (Polo-Like Kinase 1 (PLK1))
    抗原表位
    • 26
    • 17
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    • 8
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    AA 86-430
    适用
    • 132
    • 49
    • 44
    • 8
    • 8
    • 6
    • 5
    • 5
    • 5
    • 3
    • 3
    • 3
    • 1
    • 1
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    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 110
    • 21
    • 2
    • 1
    克隆类型
    • 106
    • 28
    多克隆
    标记
    • 80
    • 6
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    • 4
    • 4
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    • 2
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    This PLK1 antibody is un-conjugated
    应用范围
    • 104
    • 48
    • 31
    • 28
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    • 19
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    • 16
    • 10
    • 7
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    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    原理
    Rabbit IgG polyclonal antibody for Serine/threonine-protein kinase PLK1(PLK1) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
    交叉反应 (详细)
    No cross reactivity with other proteins.
    产品特性
    Rabbit IgG polyclonal antibody for Serine/threonine-protein kinase PLK1(PLK1) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
    Gene Name: polo-like kinase 1
    Protein Name: Serine/threonine-protein kinase PLK1
    纯化方法
    Immunogen affinity purified.
    免疫原
    E.coli-derived human PLK1 recombinant protein (Position: K86-N430). Human PLK1 shares 95.4% and 96.2% amino acid (aa) sequence identity with mouse and rat PLK1, respectively.
    亚型
    IgG
    Top Product
    Discover our top product PLK1 Primary Antibody
  • 应用备注
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human
    IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Mouse, Rat, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
    Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.
    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    浓度
    500 μg/mL
    缓冲液
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
  • 抗原
    PLK1 (Polo-Like Kinase 1 (PLK1))
    别名
    PLK1 (PLK1 产品)
    别名
    PLK antibody, STPK13 antibody, plk antibody, PLK-1 antibody, Plx1 antibody, stpk13 antibody, Plk antibody, cb525 antibody, cb636 antibody, ik:tdsubc_2d1 antibody, wu:fb37g11 antibody, wu:fb76g03 antibody, xx:tdsubc_2d1 antibody, polo like kinase 1 antibody, polo like kinase 1 S homeolog antibody, polo-like kinase 1 antibody, polo-like kinase 1 (Drosophila) antibody, Serine/threonine-protein kinase plk-1 antibody, PLK1 antibody, plk1.S antibody, plk1 antibody, Plk1 antibody, plk-1 antibody
    背景
    Serine/threonine-protein kinase PLK1, also known as polo-like kinase 1 (PLK-1) or serine/threonine-protein kinase 13(STPK13), is an enzyme that in humans is encoded by the PLK1 (polo-like kinase 1) gene. Plk1 is an early trigger for G2/M transition. It supports the functional maturation of the centrosome in late G2/early prophaseand establishment of the bipolar spindle. Also, Plk1 phosphorylates and activates cdc25C, a phosphatase that dephosphorylates and activates the cyclinB/cdc2 complex. Studies have shown that the loss of PLK1 expression can inducepro-apoptotic pathways and inhibit growth. Based on yeast and murine studies of meiosis, human PLK1 may also have a regulatory function in meiosis.

    Synonyms: Cell cycle regulated protein kinase antibody|PLK 1 antibody|PLK antibody|PLK-1 antibody| plk1 antibody|PLK1_HUMAN antibody|Polo like kinase 1 antibody|Polo-like kinase 1 antibody| Serine/threonine protein kinase 13 antibody|Serine/threonine protein kinase PLK1 antibody| Serine/threonine-protein kinase 13 antibody|Serine/threonine-protein kinase PLK1 antibody| STPK 13 antibody|STPK13 antibody
    基因ID
    5347
    UniProt
    P53350
    途径
    Cell Division Cycle, M Phase
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