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PLK1 抗体 (AA 86-430)

This anti-PLK1 antibody is a 兔多克隆 antibody detecting PLK1 in WB. Suitable for 人.

Western Blotting (WB) image for anti-Polo-Like Kinase 1 (PLK1) (AA 86-430) antibody (ABIN3043354) (PLK1 抗体 (AA 86-430))

Anti- PLK1 Picoband antibody,IHC(P) IHC(P): Rat Lymphaden Tissue (PLK1 抗体 (AA 86-430))

Anti- PLK1 Picoband antibody,IHC(P) IHC(P): Mouse Lymphaden Tissue (PLK1 抗体 (AA 86-430))

Anti- PLK1 Picoband antibody,IHC(P) IHC(P): Human Lung Cancer Tissue (PLK1 抗体 (AA 86-430))

4 images

产品编号 ABIN3043354

发货至: 中国

Datasheet as PDF

Quick Overview for PLK1 抗体 (AA 86-430) (ABIN3043354)

抗原

See all PLK1 抗体

PLK1 (Polo-Like Kinase 1 (PLK1))

适用

123
46
39
15
7
7
6
5
5
3
3
3
1
1
1
1

人

宿主

兔

克隆类型

多克隆

标记

77
6
5
4
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1

This PLK1 antibody is un-conjugated

应用范围

110
49
33
28
27
26
19
19
7
5
4
4
3
2
2
1
1

Western Blotting (WB)

Discover our top product PLK1 Primary Antibody

抗原表位
22

18

15

12

8

5

3

3

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 86-430

原理

Anti-PLK1 Antibody Picoband®

交叉反应（详细）

No cross-reactivity with other proteins

产品特性

Anti-PLK1 Antibody Picoband® (ABIN3043354). Tested in WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

纯化方法

Immunogen affinity purified.

免疫原

E.coli-derived human PLK1 recombinant protein (Position: K86-N430). Human PLK1 shares 95.4% and 96.2% amino acid (aa) sequence identity with mouse and rat PLK1, respectively.

亚型

IgG
anti-Polo-Like Kinase 1 (PLK1) (AA 331-508) antibody
PLK1 适用: 人, 小鼠 WB, ELISA, IHC, FACS 宿主: 小鼠 Monoclonal 3C11 unconjugated

anti-Polo-Like Kinase 1 (PLK1) (AA 1-603) antibody
PLK1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 4G11 unconjugated

anti-Polo-Like Kinase 1 (PLK1) (AA 1-603) antibody
PLK1 适用: 人 WB, ELISA, IF, IP, PLA 宿主: 小鼠 Monoclonal 2G12 unconjugated

anti-Polo-Like Kinase 1 (PLK1) antibody
PLK1 适用: 人 WB, IHC, IP, IHC (p), FACS 宿主: 小鼠 Monoclonal 5C1 unconjugated

anti-Polo-Like Kinase 1 (PLK1) antibody
PLK1 适用: 人, 犬 WB, IHC, IP, IHC (p) 宿主: 小鼠 Monoclonal 6C6 unconjugated

anti-Polo-Like Kinase 1 (PLK1) antibody
PLK1 适用: 人 WB, IHC, IP, IHC (p) 宿主: 小鼠 Monoclonal 1D4 unconjugated

anti-Polo-Like Kinase 1 (PLK1) antibody
PLK1 适用: 人, 犬, 猴 WB, IF, IP, FACS 宿主: 小鼠 Monoclonal 8C12 unconjugated

anti-Polo-Like Kinase 1 (PLK1) (AA 201-300) antibody
PLK1 适用: 人 WB, ELISA, IHC (p), IF (cc), IF (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Polo-Like Kinase 1 (PLK1) antibody
PLK1 适用: 人 WB, IHC, IP, IHC (p), FACS 宿主: 小鼠 Monoclonal 3F12 unconjugated

anti-Polo-Like Kinase 1 (PLK1) (AA 331-508) antibody
PLK1 适用: 人 ELISA, ICC 宿主: 小鼠 Monoclonal 1D1 unconjugated

应用备注

Western blot, 0.1-0.5 μg/mL, Human
1. Holtrich U, Wolf G, Bräuninger A, Karn T, Böhme B, Rübsamen-Waigmann H et al. (March 1994). "Induction and down-regulation of PLK, a human serine/threonine kinase expressed in proliferating cells and tumors". Proc. Natl. Acad. Sci. U.S.A. 91(5): 1736-40. 2. Soung NK, Park JE, Yu LR, Lee KH, Lee JM, Bang JK et al. (April 2009). "Plk1-dependent and -independent roles of an ODF2 splice variant, hCenexin1, at the centrosome of somatic cells". Dev. Cell 16(4): 539-50.

说明

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

限制

仅限研究用
状态

Lyophilized

溶解方式

Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

浓度

500 μg/mL

缓冲液

Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freezing and thawing.

储存条件

4 °C,-20 °C

储存方法

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
抗原

PLK1 (Polo-Like Kinase 1 (PLK1))

别名

PLK1

背景

Synonyms: Serine/threonine-protein kinase PLK1,2.7.11.21,Polo-like kinase 1,PLK-1,Serine/threonine-protein kinase 13,STPK13,PLK1,PLK,
Tissue Specificity: Placenta and colon.
Background: Serine/threonine-protein kinase PLK1, also known as polo-like kinase 1 (PLK-1) or serine/threonine-protein kinase 13 (STPK13), is an enzyme that in humans is encoded by the PLK1 (polo-like kinase 1) gene. Plk1 is an early trigger for G2/M transition. It supports the functional maturation of the centrosome in late G2/early prophaseand establishment of the bipolar spindle. Also, Plk1 phosphorylates and activates cdc25C, a phosphatase that dephosphorylates and activates the cyclinB/cdc2 complex. Studies have shown that the loss of PLK1 expression can inducepro-apoptotic pathways and inhibit growth. Based on yeast and murine studies of meiosis, human PLK1 may also have a regulatory function in meiosis.
Sequence Similarities: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CDC5/Polo subfamily.

分子量

68 kDa

基因ID

5347

UniProt

P53350

途径

Cell Division Cycle, M Phase

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