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Sp3 抗体 (C-Term)

Sp3 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3043350
发货至: 中国
  • 抗原 See all Sp3 抗体
    Sp3 (Sp3 Transcription Factor (Sp3))
    抗原表位
    • 14
    • 7
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 569-599, C-Term
    适用
    • 38
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    人, 小鼠, 大鼠
    宿主
    • 34
    • 4
    克隆类型
    • 34
    • 4
    多克隆
    标记
    • 17
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Sp3 antibody is un-conjugated
    应用范围
    • 33
    • 19
    • 12
    • 12
    • 6
    • 5
    • 4
    • 3
    • 3
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    原理
    Anti-SP3 Antibody Picoband®
    序列
    NTNDLTHLRV QVVDEEGDQQ HQEGKRLRRV A
    交叉反应 (详细)
    No cross-reactivity with other proteins
    产品特性
    Anti-SP3 Antibody Picoband® (ABIN3043350). Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
    纯化方法
    Immunogen affinity purified.
    免疫原
    A synthetic peptide corresponding to a sequence at the C-terminus of human SP3, identical to the related mouse sequence.
    亚型
    IgG
    Top Product
    Discover our top product Sp3 Primary Antibody
  • 应用备注
    Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human, Mouse, Rat
    Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
    1. "Entrez Gene: SP3 Sp3 transcription factor". 2. Sun, Jian-Min, Chen Hou Yu, Moniwa Mariko, Litchfield David W, Seto Edward, Davie James R (September 2002). "The transcriptional repressor Sp3 is associated with CK2-phosphorylated histone deacetylase 2". J. Biol. Chem.(United States) 277 (39): 35783-6.
    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    浓度
    500 μg/mL
    缓冲液
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C,-20 °C
    储存方法
    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • 抗原
    Sp3 (Sp3 Transcription Factor (Sp3))
    别名
    SP3 (Sp3 产品)
    背景

    Synonyms: Transcription factor Sp3,SPR-2,SP3,

    Tissue Specificity: Ubiquitously expressed.

    Background: Sp3 transcription factor, also known as SP3, refers to both a protein and the gene it is encoded by. This gene belongs to a family of Sp1 related genes that encode transcription factors that regulate transcription by binding to consensus GC- and GT-box regulatory elements in target genes. And this protein contains a zinc finger DNA-binding domain and several transactivation domains, and has been reported to function as a bifunctional transcription factor that either stimulates or represses the transcription of numerous genes. Transcript variants encoding different isoforms have been described for this gene, and one has been reported to initiate translation from a non-AUG (AUA) start codon. Additional isoforms, resulting from the use of alternate downstream translation initiation sites, have also been noted. A related pseudogene has been identified on chromosome 13.

    Sequence Similarities: Belongs to the Sp1 C2H2-type zinc-finger protein family.

    分子量
    82 kDa
    基因ID
    6670
    UniProt
    Q02447
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