SOCS4 抗体 (AA 291-440)
Quick Overview for SOCS4 抗体 (AA 291-440) (ABIN3043346)
抗原
See all SOCS4 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 291-440
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原理
- Anti-SOCS4 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins
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产品特性
- Anti-SOCS4 Antibody Picoband® (ABIN3043346). Tested in WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human SOCS4 recombinant protein (Position: M291-C440). Human SOCS4 shares 98% amino acid (aa) sequence identity with mouse SOCS4.
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亚型
- IgG
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anti-Suppressor of Cytokine Signaling 4 (SOCS4) (AA 227-254) antibody
SOCS4 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Suppressor of Cytokine Signaling 4 (SOCS4) (AA 1-270) antibodySOCS4 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Suppressor of Cytokine Signaling 4 (SOCS4) (C-Term) antibodySOCS4 适用: 人 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-Suppressor of Cytokine Signaling 4 (SOCS4) (AA 1-440) antibodySOCS4 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2G8 unconjugated
anti-Suppressor of Cytokine Signaling 4 (SOCS4) (AA 1-440) antibodySOCS4 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Suppressor of Cytokine Signaling 4 (SOCS4) (AA 227-254) antibodySOCS4 适用: 人 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB31389 unconjugated
anti-Suppressor of Cytokine Signaling 4 (SOCS4) (AA 234-262) antibodySOCS4 适用: 人 WB, IF, IHC (p), EIA, FACS 宿主: 兔 Polyclonal unconjugated
anti-Suppressor of Cytokine Signaling 4 (SOCS4) (AA 1-440) antibodySOCS4 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Suppressor of Cytokine Signaling 4 (SOCS4) (C-Term) antibodyVerified SOCS4 适用: 人 ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Suppressor of Cytokine Signaling 4 (SOCS4) (AA 224-253) antibodySOCS4 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.1-0.5 μg/mL, Human
1. Bullock AN, Rodriguez MC, Debreczeni JE, Songyang Z, Knapp S. ""Structure of the SOCS4-ElonginB/C complex reveals a distinct SOCS box interface and the molecular basis for SOCS-dependent EGFR degradation"". Structure, 2007 Nov. 2. Kobayashi D, Nomoto S, Kodera Y, Fujiwara M, Koike M, Nakayama G, Ohashi N, Nakao A. ""Suppressor of cytokine signaling 4 detected as a novel gastric cancer suppressor gene using double combination array analysis"". World J Surg, 2012 Feb. -
说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- SOCS4 (Suppressor of Cytokine Signaling 4 (SOCS4))
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别名
- SOCS4
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背景
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Synonyms: Suppressor of cytokine signaling 4,SOCS-4,Suppressor of cytokine signaling 7,SOCS-7,SOCS4,SOCS7,
Tissue Specificity: Placenta, liver, and to a much smaller extent, in lung.
Background: SOCS4, also known as Suppressor of cytokine signaling 4, is mapped to 14q22.1. The protein encoded by this gene contains a SH2 domain and a SOCS BOX domain. The protein thus belongs to the suppressor of cytokine signaling (SOCS), also known as STAT-induced STAT inhibitor (SSI), protein family. SOCS family members are known to be cytokine-inducible negative regulators of cytokine signaling. Two alternatively spliced transcript variants encoding the same protein have been found for this gene.
Sequence Similarities: Contains 1 SH2 domain.
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分子量
- 51 kDa
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基因ID
- 122809
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途径
- JAK/STAT Signaling, EGFR Signaling Pathway
抗原
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