-
- 抗原 See all SEMA3A 抗体
- SEMA3A (Sema Domain, Immunoglobulin Domain (Ig), Short Basic Domain, Secreted, (Semaphorin) 3A (SEMA3A))
-
抗原表位
- AA 550-771
-
适用
- 人
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This SEMA3A antibody is un-conjugated
-
应用范围
- Western Blotting (WB)
- 原理
- Anti-Semaphorin 3A/SEMA3A Antibody Picoband®
- 交叉反应 (详细)
- No cross-reactivity with other proteins.
- 产品特性
- Anti-Semaphorin 3A/SEMA3A Antibody Picoband® (ABIN3043328). Tested in WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
- 纯化方法
- Immunogen affinity purified.
- 免疫原
- E.coli-derived human Semaphorin 3A recombinant protein (Position: K550-V771). Human Semaphorin 3A shares 93% and 94% amino acid (aa) sequence identity with mouse and rat Semaphorin 3A, respectively.
- 亚型
- IgG
- Top Product
- Discover our top product SEMA3A Primary Antibody
-
-
- 应用备注
-
Western blot, 0.1-0.5 μg/mL, Human
1. Nakano Y, et al. A nonsynonymous polymorphism in semaphorin 3A as a risk factor for human unexplained cardiac arrest with documented ventricular fibrillation. PLoS Genet, 2013 Apr. 2. Takagawa S, et al. Decreased semaphorin3A expression correlates with disease activity and histological features of rheumatoid arthritis. BMC Musculoskelet Disord, 2013 Jan 23. 3. Vadasz Z, et al. The role of B regulatory cells and Semaphorin3A in atopic diseases. Int Arch Allergy Immunol, 2014. - 说明
-
Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
- 限制
- 仅限研究用
-
- 状态
- Lyophilized
- 溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- 浓度
- 500 μg/mL
- 缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C,-20 °C
- 储存方法
-
Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
-
-
Significance of semaphorin-3A and MMP-14 protein expression in non-small cell lung cancer." in: Oncology letters, Vol. 7, Issue 5, pp. 1395-1400, (2014) (PubMed).
: "
-
Significance of semaphorin-3A and MMP-14 protein expression in non-small cell lung cancer." in: Oncology letters, Vol. 7, Issue 5, pp. 1395-1400, (2014) (PubMed).
-
- 抗原
- SEMA3A (Sema Domain, Immunoglobulin Domain (Ig), Short Basic Domain, Secreted, (Semaphorin) 3A (SEMA3A))
- 别名
- SEMA3A (SEMA3A 产品)
- 背景
-
Synonyms: Semaphorin-3A,Semaphorin III,Sema III,SEMA3A,SEMAD,
Background: SEMA3A is also known as COLL1, SEMA1 or SEMAL. This gene is a member of the semaphorin family and encodes a protein with an Ig-like C2-type (immunoglobulin-like) domain, a PSI domain and a Sema domain. This secreted protein can function as either a chemorepulsive agent, inhibiting axonal outgrowth, or as a chemoattractive agent, stimulating the growth of apical dendrites. In both cases, the protein is vital for normal neuronal pattern development. Increased expression of this protein is associated with schizophrenia and is seen in a variety of human tumor cell lines. Also, aberrant release of this protein is associated with the progression of Alzheimer's disease.
Sequence Similarities: Belongs to the semaphorin family.
- 分子量
- 89 kDa
- 基因ID
- 10371
- UniProt
- Q14563
- 途径
- Regulation of Cell Size
-