KNG1 抗体 (Middle Region)
Quick Overview for KNG1 抗体 (Middle Region) (ABIN3043285)
抗原
See all KNG1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 227-259, Middle Region
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原理
- Anti-Kininogen 1/KNG1 Antibody Picoband®
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序列
- ECRGNLFMDI NNKIANFSQS CTLYSGDDLV EA
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交叉反应 （详细）
- No cross-reactivity with other proteins
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产品特性
- Anti-Kininogen 1/KNG1 Antibody Picoband® (ABIN3043285). Tested in IHC, WB applications. This antibody reacts with Mouse. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence in the middle region of mouse Kininogen 1, different from the related rat sequence by thirteen amino acids.
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亚型
- IgG
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anti-Kininogen 1 (KNG1) (AA 225-407) antibody
KNG1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Kininogen 1 (KNG1) (AA 390-644) antibodyKNG1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Kininogen 1 (KNG1) (AA 214-475) antibodyKNG1 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Kininogen 1 (KNG1) (AA 268-540) antibodyKNG1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Kininogen 1 (KNG1) (N-Term) antibodyKNG1 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Kininogen 1 (KNG1) (AA 19-380) antibodyKNG1 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Kininogen 1 (KNG1) (AA 148-427) antibodyKNG1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Kininogen 1 (KNG1) (AA 22-379) antibodyKNG1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Kininogen 1 (KNG1) (AA 390-644) antibodyKNG1 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Kininogen 1 (KNG1) (AA 1-427) antibodyKNG1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
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应用备注
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Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Mouse
Western blot, 0.1-0.5 μg/mL, Mouse
1. "Entrez Gene: kininogen 1". 2. Fong, D., Smith, D. I., Hsieh, W.-T. The human kininogen gene (KNG) mapped to chromosome 3q26-qter by analysis of somatic cell hybrids using the polymerase chain reaction. Hum. Genet. 87: 189-192, 1991. -
说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- KNG1 (Kininogen 1 (KNG1))
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别名
- Kng1
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背景
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Synonyms: Kininogen-1,Kininogen-1 heavy chain,Bradykinin,Kininogen-1 light chain,Kng1,Kng,
Tissue Specificity: Plasma.
Background: Kininogen-1 (KNG1), also known as BDK or bradykinin, is a protein that in humans is encoded by the KNG1 gene. It is mapped to 3q27.3. The KNG1 gene uses alternative splicing to generate two different proteins - high - molecular - weight kininogen (HMWK) and low - molecular- weight kininogen (LMWK). HMWK is essential for blood coagulation and assembly of the kallikrein-kinin system. Also, KNG1, a peptide causing numerous physiological effects, is released from HMWK. In contrast to HMWK, LMWK is not involved in blood coagulation. In addition to that, KNG1 is a constituent of the blood coagulation system as well as the kinin-kallikrein system.
Sequence Similarities: Contains 1 HMG box DNA-binding domain.
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分子量
- 73 kDa
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基因ID
- 16644
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UniProt
- O08677
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途径
- ACE Inhibitor Pathway, Glycosaminoglycan Metabolic Process
抗原
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