KIF3A 抗体 (AA 485-699)
Quick Overview for KIF3A 抗体 (AA 485-699) (ABIN3043279)
抗原
See all KIF3A 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 485-699
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原理
- Anti-KIF3A Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins
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产品特性
- Anti-KIF3A Antibody Picoband® (ABIN3043279). Tested in WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human KIF3A recombinant protein (Position: D485-Q699). Human KIF3A shares 97.7% amino acid (aa) sequence identity with mouse KIF3A.
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亚型
- IgG
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anti-Kinesin Family Member 3A (KIF3A) (AA 430-699) antibody
KIF3A 适用: 人 WB, IP, IF 宿主: 兔 Polyclonal unconjugated
anti-Kinesin Family Member 3A (KIF3A) (AA 430-699) antibodyKIF3A 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Kinesin Family Member 3A (KIF3A) antibodyKIF3A 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Kinesin Family Member 3A (KIF3A) antibodyKIF3A 适用: 人 WB, IHC, IF 宿主: 兔 Monoclonal unconjugated
anti-Kinesin Family Member 3A (KIF3A) (AA 1-702) antibodyKIF3A 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Kinesin Family Member 3A (KIF3A) (C-Term) antibodyKIF3A 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Kinesin Family Member 3A (KIF3A) antibodyKIF3A 适用: 人, 小鼠, 大鼠 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-Kinesin Family Member 3A (KIF3A) antibodyKIF3A 适用: 人, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Kinesin Family Member 3A (KIF3A) (C-Term) antibodyKIF3A 适用: 人, 犬, Cow, 豚鼠, 马, 兔, 斑马鱼, Bat, 小鸡, 猴, Pig, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
anti-Kinesin Family Member 3A (KIF3A) (C-Term) antibodyKIF3A 适用: 人, 犬 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
1. Cole DG, Chinn SW, Wedaman KP, Hall K, Vuong T, Scholey JM (November 1993). "Novel heterotrimeric kinesin-related protein purified from sea urchin eggs". Nature 366 (6452): 268-70. 2. Nonaka S, Tanaka Y, Okada Y, Takeda S, Harada A, Kanai Y, Kido M, Hirokawa N (December 1998). "Randomization of left-right asymmetry due to loss of nodal cilia generating leftward flow of extraembryonic fluid in mice lacking KIF3B motor protein". Cell 95 (6): 829-37. 3. Rosenbaum JL, Witman GB (November 2002). "Intraflagellar transport". Nat. Rev. Mol. Cell Biol. 3 (11): 813-25. -
说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- KIF3A (Kinesin Family Member 3A (KIF3A))
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别名
- KIF3A
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背景
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Synonyms: Kinesin-like protein KIF3A,Microtubule plus end-ed kinesin motor 3A,KIF3A,KIF3,
Tissue Specificity: Cornea. Increased expression in the stroma of keratoconus corneas. Also detected in trachea, and in low levels, in intestine, skeletal muscle, ovary, lung and putamen. .
Background: Kinesin-like protein KIF3A is a protein that in humans is encoded by the KIF3A gene. KIF3A is one subunit of the heterotrimeric motor protein, kinesin-2, that was initially isolated from sea urchin egg/embryo cytosol using microtubule affinity purification. This motor consists of two kinesin-related subunits (called KIF3A and KIF3B or 3C in vertebrates) and an associated protein (KAP3), and it transports protein complexes, nucleic acids and organelles towards the "plus" ends of microtubule tracks within cells. Work done in a broad range of eukaryotic cells has revealed that heterotrimeric kinesin-2 is the primary motor protein driving the intra-flagellar transport of tubulins and other axonemal building blocks from the base of the ciliary/flagellar axoneme to their site of assembly at the distal tips. This process is required for cilium assembly/maintenance and cilium-based signalling which play key roles in various cell and developmental processes. For example, in vertebrate embryos, kinesin-2 function is required for cilia-dependent nodal flow and the development of left-right asymmetry.
Sequence Similarities: Contains 1 HMG box DNA-binding domain.
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分子量
- 80 kDa
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基因ID
- 11127
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UniProt
- Q9Y496
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途径
- Hedgehog Signaling
抗原
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