IL2 Receptor beta 抗体 (C-Term)
Quick Overview for IL2 Receptor beta 抗体 (C-Term) (ABIN3043246)
抗原
See all IL2 Receptor beta (IL2RB) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 503-539, C-Term
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原理
- Anti-IL2 Receptor beta/IL2RB Antibody Picoband®
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序列
- NLHGQDQDRG QGPILTLNTD AYLSLQELQA QDSVHLI
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-IL2 Receptor beta/IL2RB Antibody Picoband® (ABIN3043246). Tested in WB applications. This antibody reacts with Mouse. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the C-terminus of mouse IL2RB, different from the related human sequence by sixteen amino acids, and from the related rat sequence by fourteen amino acids.
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亚型
- IgG
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anti-Interleukin 2 Receptor, beta (IL2RB) (AA 27-240) antibody
IL2RB 适用: 人 FACS, ELISA 宿主: 小鼠 Monoclonal 1G11C6 unconjugated
anti-Interleukin 2 Receptor, beta (IL2RB) (Internal Region) antibodyIL2RB 适用: 小鼠, 人, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 2 Receptor, beta (IL2RB) antibodyIL2RB 适用: 人 FACS, IP, Func 宿主: 小鼠 Monoclonal TU27 unconjugated
anti-Interleukin 2 Receptor, beta (IL2RB) antibodyIL2RB 适用: 人 FACS, IP 宿主: 小鼠 Monoclonal TU27 unconjugated
anti-Interleukin 2 Receptor, beta (IL2RB) antibody (APC)IL2RB 适用: 人 FACS 宿主: 小鼠 Monoclonal TU27 APC
anti-Interleukin 2 Receptor, beta (IL2RB) (Tyr364) antibodyIL2RB 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 2 Receptor, beta (IL2RB) (AA 1-551) antibodyIL2RB 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 2 Receptor, beta (IL2RB) (AA 1-551) antibodyIL2RB 适用: 人 WB, FACS 宿主: 小鼠 Polyclonal unconjugated
anti-Interleukin 2 Receptor, beta (IL2RB) (N-Term) antibodyIL2RB 适用: 小鼠, 人 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 2 Receptor, beta (IL2RB) (AA 27-240) antibodyIL2RB 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.1-0.5 μg/mL, Mouse
1. Campbell, H. D., Webb, G. C., Kono, T., Taniguchi, T., Ford, J. H., Young, I. G. Assignment of the interleukin-2 receptor beta chain gene (Il-2rb) to band E on mouse chromosome 15. Genomics 12: 179-180, 1992. 2. Dai, H., Wan, N., Zhang, S., Moore, Y., Wan, F., Dai, Z. Cutting edge: programmed death-1 defines CD8+CD122+ T cells as regulatory versus memory T cells. J. Immun. 185: 803-807, 2010. 3. Yamashita, Yuki, Kojima Katsuhiko, Tsukahara Tomonori, Agawa Hideyuki, Yamada Koichiro, Amano Yuji, Kurotori Naoki, Tanaka Nobuyuki, Sugamura Kazuo, Takeshita Toshikazu (May. 2008). "Ubiquitin-independent binding of Hrs mediates endosomal sorting of the interleukin-2 receptor beta-chain". J. Cell. Sci. (England) 121 (Pt 10): 1727-38. doi:10.1242/jcs.024455. -
说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- IL2 Receptor beta (IL2RB) (Interleukin 2 Receptor, beta (IL2RB))
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别名
- Il2rb
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背景
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Synonyms: Interleukin-2 receptor subunit beta,IL-2 receptor subunit beta,IL-2R subunit beta,IL-2RB,High affinity IL-2 receptor subunit beta,p70-75,CD122,Il2rb,
Tissue Specificity: Expressed in lung (at protein level). Expressed predominantly in lung, and at a much lesser extent in kidney. Also expressed in fetal lung, but not in liver, kidney and brain. .
Background: IL2RB (INTERLEUKIN 2 RECEPTOR, BETA), also called CD122, is a protein that in humans is encoded by the IL2RB gene. The gene represents the beta subunit and is a type I membrane protein. IL2RB is mapped to 22q12.3. The IL2RB gene contains 10 exons spanning about 24.3 kb and that the gene product is encoded by exons 2-10. The IL2 receptor is present in 3 forms with respect to binding ability to IL2: high, intermediate, and low affinity forms. Analysis of mutants of the beta chain of the IL2 receptor reveals that the granulocyte and monocyte differentiation signals are triggered by different cytoplasmic domains, showing that the signaling pathways responsible for these unique developmental outcomes are separable.
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分子量
- 75 kDa
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基因ID
- 16185
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UniProt
- P16297
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途径
- JAK/STAT Signaling, Growth Factor Binding
抗原
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