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IL2 Receptor beta 抗体 (C-Term)

This anti-IL2 Receptor beta antibody is a 兔 多克隆 antibody detecting IL2 Receptor beta in WB. Suitable for 小鼠.
产品编号 ABIN3043246
发货至: 中国
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Quick Overview for IL2 Receptor beta 抗体 (C-Term) (ABIN3043246)

抗原

See all IL2 Receptor beta (IL2RB) 抗体
IL2 Receptor beta (IL2RB) (Interleukin 2 Receptor, beta (IL2RB))

适用

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小鼠

宿主

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克隆类型

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多克隆

标记

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This IL2 Receptor beta antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    AA 503-539, C-Term

    原理

    Anti-IL2 Receptor beta/IL2RB Antibody

    序列

    NLHGQDQDRG QGPILTLNTD AYLSLQELQA QDSVHLI

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    产品特性

    Anti-IL2 Receptor beta/IL2RB Antibody (ABIN3043246). Tested in WB applications. This antibody reacts with Mouse. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence at the C-terminus of mouse IL2RB, different from the related human sequence by sixteen amino acids, and from the related rat sequence by fourteen amino acids.

    亚型

    IgG
  • 应用备注

    Western blot, 0.1-0.5 μg/mL, Mouse

    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • 抗原

    IL2 Receptor beta (IL2RB) (Interleukin 2 Receptor, beta (IL2RB))

    别名

    Il2rb

    背景

    Synonyms: Interleukin-2 receptor subunit beta,IL-2 receptor subunit beta,IL-2R subunit beta,IL-2RB,High affinity IL-2 receptor subunit beta,p70-75,CD122,Il2rb,

    Tissue Specificity: Expressed in lung (at protein level). Expressed predominantly in lung, and at a much lesser extent in kidney. Also expressed in fetal lung, but not in liver, kidney and brain. .

    Background: IL2RB (INTERLEUKIN 2 RECEPTOR, BETA), also called CD122, is a protein that in humans is encoded by the IL2RB gene. The gene represents the beta subunit and is a type I membrane protein. IL2RB is mapped to 22q12.3. The IL2RB gene contains 10 exons spanning about 24.3 kb and that the gene product is encoded by exons 2-10. The IL2 receptor is present in 3 forms with respect to binding ability to IL2: high, intermediate, and low affinity forms. Analysis of mutants of the beta chain of the IL2 receptor reveals that the granulocyte and monocyte differentiation signals are triggered by different cytoplasmic domains, showing that the signaling pathways responsible for these unique developmental outcomes are separable.

    分子量

    75 kDa

    基因ID

    16185

    UniProt

    P16297

    途径

    JAK/STAT Signaling, Growth Factor Binding
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