Caspase 6 抗体 (N-Term)
Quick Overview for Caspase 6 抗体 (N-Term) (ABIN3043219)
抗原
See all Caspase 6 (CASP6) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 24-44, N-Term
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原理
- Anti-Caspase-6(P18)/CASP6 Antibody Picoband®
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序列
- AFYKREMFDP AEKYKMDHRR R
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交叉反应 （详细）
- No cross-reactivity with other proteins
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产品特性
- Anti-Caspase-6 (P18)/CASP6 Antibody (ABIN3043219). Tested in Flow Cytometry, IHC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the N-terminus of human Caspase-6(P18).
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亚型
- IgG
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anti-Caspase 6, Apoptosis-Related Cysteine Peptidase (CASP6) (AA 194-293) antibody
CASP6 适用: Cow WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Caspase 6, Apoptosis-Related Cysteine Peptidase (CASP6) (AA 81-179) antibodyCASP6 适用: Cow WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Caspase 6, Apoptosis-Related Cysteine Peptidase (CASP6) (AA 194-293) antibodyCASP6 适用: 人 ELISA, ICC, FACS 宿主: 小鼠 Monoclonal 3B7E10 unconjugated
anti-Caspase 6, Apoptosis-Related Cysteine Peptidase (CASP6) (AA 7-27) antibodyCASP6 适用: 小鼠, 大鼠 WB, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Caspase 6, Apoptosis-Related Cysteine Peptidase (CASP6) (AA 81-179) antibodyCASP6 适用: Cow WB, IHC 宿主: 小鼠 Monoclonal C1 unconjugated
anti-Caspase 6, Apoptosis-Related Cysteine Peptidase (CASP6) (AA 7-27), (N-Term) antibodyCASP6 适用: 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Caspase 6, Apoptosis-Related Cysteine Peptidase (CASP6) (AA 151-250) antibodyCASP6 适用: 人 ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Caspase 6, Apoptosis-Related Cysteine Peptidase (CASP6) (AA 24-293) antibodyCASP6 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Caspase 6, Apoptosis-Related Cysteine Peptidase (CASP6) (Cleaved-Asp179) antibodyCASP6 适用: 人, 大鼠 WB, IHC, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Caspase 6, Apoptosis-Related Cysteine Peptidase (CASP6) (AA 1-293) antibodyCASP6 适用: 人 WB, PLA 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.1-0.5 μg/mL, Human
Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
1. Fernandes-Alnemri, T., Litwack, G., Alnemri, E. S.Mch2, a new member of the apoptotic Ced-3/Ice cysteine protease gene family.Cancer Res. 55: 2737-2742, 1995. 2. Nikolaev, A., McLaughlin, T., O'Leary, D. D. M., Tessier-Lavigne, M.APP binds DR6 to trigger axon pruning and neuron death via distinct caspases Nature 457: 981-989, 2009. 3. Orth, K., Chinnaiyan, A. M., Garg, M., Froelich, C. J., Dixit, V. M.The CED-3/ICE-like protease Mch2 is activated during apoptosis and cleaves the death substrate lamin A.J. Biol. Chem. 271: 16443-16446, 1996. -
说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles. -
有效期
- 12 months
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- Caspase 6 (CASP6) (Caspase 6, Apoptosis-Related Cysteine Peptidase (CASP6))
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别名
- CASP6
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背景
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Synonyms: Caspase-6,CASP-6,3.4.22.59,Apoptotic protease Mch-2,Caspase-6 subunit p18,Caspase-6 subunit p11,CASP6,MCH2,
Tissue Specificity: High level expression seen in spleen and lung, low level expression seen in brain, heart, liver, kidney, testis and skeletal muscle.
Background: Caspase 6 is an enzyme that in humans is encoded by the caspase 6 gene. This gene encodes a protein that is a member of the cysteine-aspartic acid protease (caspase) family. Using radiation hybrid mapping, the Caspase 6 gene is localized to human chromosome 4q25-q26. Caspase 6 functions as a downstream enzyme in the caspase activation cascade. And Caspase 6 can cleave lamin A to its signature apoptotic fragment.
Sequence Similarities: Belongs to the peptidase C14A family.
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分子量
- 35 kDa
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UniProt
- P55212
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途径
- Apoptosis, Caspase Cascade in Apoptosis
抗原
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