beta Defensin 1 抗体 (C-Term)
Quick Overview for beta Defensin 1 抗体 (C-Term) (ABIN3043211)
抗原
See all beta Defensin 1 (DEFB1) 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 52-68, C-Term
-
原理
- Anti-beta Defensin 1/DEFB1 Antibody Picoband®
-
序列
- FTKIQGTCYR GKAKCCK
-
交叉反应 （详细）
- No cross-reactivity with other proteins
-
产品特性
- Anti-beta Defensin 1/DEFB1 Antibody (ABIN3043211). Tested in IHC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
-
纯化方法
- Immunogen affinity purified.
-
免疫原
- A synthetic peptide corresponding to a sequence at the C-terminus of human beta Defensin 1.
-
亚型
- IgG
-
-
anti-Defensin, beta 1 (DEFB1) (AA 33-68) antibody
DEFB1 适用: 人, 大鼠 ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Defensin, beta 1 (DEFB1) (AA 22-69) antibodyDEFB1 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Defensin, beta 1 (DEFB1) (AA 22-69) antibodyDEFB1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Defensin, beta 1 (DEFB1) antibody (Biotin)DEFB1 适用: 人 WB, EIA 宿主: 兔 Polyclonal Biotin
anti-Defensin, beta 1 (DEFB1) (AA 24-64) antibodyDEFB1 适用: Pig WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Defensin, beta 1 (DEFB1) (AA 2-64) antibodyDEFB1 适用: Cow WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Defensin, beta 1 (DEFB1) (AA 22-68) antibodyDEFB1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
-
Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human
Western blot, 0.1-0.5 μg/mL, Human
1. Jia, H. P., Starner, T., Ackermann, M., Kirby, P., Tack, B. F., McCray, P. B., Jr.Abundant human beta-defensin-1 expression in milk and mammary gland epithelium.J. 2. Liu, L., Zhao, C., Heng, H. H. Q., Ganz, T.The human beta-defensin-1 and alpha-defensins are encoded by adjacent genes: two peptide families with differing disulfide topology share a common ancestry. 3. Valore, E. V., Park, C. H., Quayle, A. J., Wiles, K. R., McCray, P. B., Jr., Ganz, T.Human beta-defensin-1: an antimicrobial peptide of urogenital tissues.J. Clin. -
说明
-
Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
-
浓度
- 500 μg/mL
-
缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
-
储存液
- Thimerosal (Merthiolate), Sodium azide
-
注意事项
- This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
-
注意事项
- Avoid repeated freezing and thawing.
-
储存条件
- 4 °C,-20 °C
-
储存方法
-
Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles. -
有效期
- 12 months
-
-
- beta Defensin 1 (DEFB1) (Defensin, beta 1 (DEFB1))
-
别名
- DEFB1
-
背景
-
Synonyms: Beta-defensin 1,BD-1,hBD-1,Defensin, beta 1,DEFB1,BD1, HBD1,
Tissue Specificity: Plasma.
Background: DEFB1,Beta-defensin 1, is a protein that in humans is encoded by the DEFB1 gene. DEFB1 belongs to the defensin family. Defensins form a family of microbicidal and cytotoxic peptides made by neutrophils. The DEFB1 gene spans more than 7 kb and includes a large 6,962-bp intron. By 2-color fluorescence in situ hybridization on both metaphase chromosomes and released chromatin fiber, the DEFB1gene is mapped to 8p23.2-p23.1, within 100 to 150 kb of the gene for human neutrophil defensin-alpha-1. DEFB1may augment neonatal host defenses through antimicrobial effects or prime the adaptive immune system at mucosal surfaces.
Sequence Similarities: Belongs to the beta-defensin family.
-
分子量
- 7 kDa
-
UniProt
- P60022
抗原
-
