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FGF10 抗体 (N-Term)

This anti-FGF10 antibody is a 兔 多克隆 antibody detecting FGF10 in WB. Suitable for 人, 大鼠 和 小鼠.
产品编号 ABIN3043208
发货至: 中国

Quick Overview for FGF10 抗体 (N-Term) (ABIN3043208)

抗原

See all FGF10 抗体
FGF10 (Fibroblast Growth Factor 10 (FGF10))

适用

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人, 大鼠, 小鼠

宿主

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克隆类型

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多克隆

标记

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This FGF10 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    AA 76-91, N-Term

    原理

    Anti-Fibroblast growth factor 10 FGF10 Antibody Picoband®

    序列

    DVRWRKLFSF TKYFLK

    交叉反应 (详细)

    No cross-reactivity with other proteins

    产品特性

    Anti-Fibroblast growth factor 10 FGF10 Antibody (ABIN3043208). Tested in WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence at the N-terminus of human FGF10, different from the related mouse and rat sequence by two amino acids.

    亚型

    IgG
  • 应用备注

    Western blot, 0.1-0.5 μg/mL, Human, Rat, Mouse
    1. Bagai, S., Rubio, E., Cheng, J.-F., Sweet, R., Thomas, R., Fuchs, E., Grady, R., Mitchell, M., Bassuk, J. A.Fibroblast growth factor-10 is a mitogen for urothelial cells.J. Biol. Chem. 277: 23828-23837, 2002. 2. Emoto, H., Tagashira, S., Mattei, M.-G., Yamasaki, M., Hashimoto, G., Katsumata, T., Negoro, T., Nakatsuka, M., Birnbaum, D., Coulier, F., Itoh, N.Structure and expression of human fibroblast growth factor-10.J. Biol. Chem. 272: 23191-23194, 1997. 3. Umemori, H., Linhoff, M. W., Ornitz, D. M., Sanes, J. R.FGF22 and its close relatives are presynaptic organizing molecules in the mammalian brain.Cell 118: 257-270, 2004.

    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

    储存液

    Thimerosal (Merthiolate), Sodium azide

    注意事项

    This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    FGF10 (Fibroblast Growth Factor 10 (FGF10))

    别名

    FGF10

    背景

    Synonyms: Fibroblast growth factor 10,FGF-10,Keratinocyte growth factor 2,FGF10,

    Background: FGF 10, Fibroblast growth factor 10, is a protein that in humans is encoded by the FGF10 gene.The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF 10 contains 3 exons and spans at least 52.7 kb. By radioactive in situ hybridization, the FGF 10 gene is mapped to 5p13-p12. This protein exhibits mitogenic activity for keratinizing epidermal cells, but essentially no activity for fibroblasts. FGF 10 translocated into urothelial cell nuclei and initiated a signaling cascade that began with the heparin-dependent tyrosine phosphorylation of surface transmembrane receptors.

    Sequence Similarities: Belongs to the heparin-binding growth factors family.

    分子量

    23 kDa

    UniProt

    O15520

    途径

    RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Stem Cell Maintenance, Tube Formation, Positive Regulation of Response to DNA Damage Stimulus
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