IL23A 抗体 (N-Term)
Quick Overview for IL23A 抗体 (N-Term) (ABIN3043197)
抗原
See all IL23A 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 29-48, N-Term
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原理
- Anti-IL23 P19/IL23A Antibody Picoband®
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序列
- DWAQCQQLSR NLCMLAWNAH
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交叉反应 （详细）
- No cross-reactivity with other proteins
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产品特性
- Anti-IL23 P19/IL23A Antibody (ABIN3043197). Tested in WB applications. This antibody reacts with Mouse. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the N-terminus of mouse IL23 P19, different from the related rat sequence by two amino acids.
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亚型
- IgG
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anti-Interleukin 23, alpha subunit p19 (IL23A) (C-Term) antibody
IL23A 适用: 人 WB, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 23, alpha subunit p19 (IL23A) (AA 1-189) antibodyIL23A 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4C8 unconjugated
anti-Interleukin 23, alpha subunit p19 (IL23A) (AA 20-189) antibodyIL23A 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 23, alpha subunit p19 (IL23A) (N-Term) antibodyIL23A 适用: 人, 小鼠 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 23, alpha subunit p19 (IL23A) antibodyIL23A 适用: 人, 小鼠 WB, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 23, alpha subunit p19 (IL23A) (AA 20-155) antibodyIL23A 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 23, alpha subunit p19 (IL23A) (AA 33-67) antibodyIL23A 适用: 人, 小鼠 WB, FACS 宿主: 兔 Polyclonal RB56752 unconjugated
anti-Interleukin 23, alpha subunit p19 (IL23A) (AA 1-189) antibodyIL23A 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 23, alpha subunit p19 (IL23A) antibodyIL23A 适用: 人 WB, ELISA 宿主: 兔 Monoclonal 1F6 unconjugated Recombinant Antibody
anti-Interleukin 23, alpha subunit p19 (IL23A) (AA 1-189) antibodyIL23A 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
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应用备注
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Western blot, 0.1-0.5 μg/mL, Mouse
1. Hu, W., Dehmel, T., Pirhonen, J., Hartung, H.-P., Kieseier, B. C.Interleukin 23 in acute inflammatory demyelination of the peripheral nerve.Arch. Neurol. 63: 858-864, 2006. 2. Kullberg, M. C., Jankovic, D., Feng, C. G., Hue, S., Gorelick, P. L., McKenzie, B. S., Cua, D. J., Powrie, F., Cheever, A. W., Maloy, K. J., Sher, A.IL-23 plays a key role in Helicobacter hepaticus-induced T cell-dependent colitis.J. Exp. Med. 203: 2485-2494, 2006. 3. Oppmann, B., Lesley, R., Blom, B., Timans, J. C., Xu, Y., Hunte, B., Vega, F., Yu, N., Wang, J., Singh, K., Zonin, F., Vaisberg, E., and 13 others.Novel p19 protein engages IL-12p40 to form a cytokine, IL-23, with biological activities similar as well as distinct from IL-12.Immunity 13: 715-725, 2000. -
说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
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储存液
- Thimerosal (Merthiolate), Sodium azide
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注意事项
- This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles. -
有效期
- 12 months
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- IL23A (Interleukin 23, alpha subunit p19 (IL23A))
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别名
- IL23A
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背景
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Synonyms: Interleukin-23 subunit alpha,IL-23 subunit alpha,IL-23-A,Interleukin-23 subunit p19,IL-23p19,Il23a,
Tissue Specificity: Secreted by activated dendritic cells (at protein level). Detected in various tissues with higher expression in polarized Th1 cells and activated macrophages. .
Background: IL-23, Interleukin-23, also known as Interleukin-23 subunit alphainin (IL23A), is a heterodimeric cytokine consisting of two subunits, one called p40, which is shared with another cytokine, IL-12, and another called p19 (the IL-23 alpha subunit). The International Radiation Hybrid Mapping Consortium mapped the IL-23 gene to chromosome 12. IL-23 is an important part of the inflammatory response against infection. It promotes upregulation of the matrix metalloprotease MMP9, increases angiogenesis and reduces CD8+ T-cell infiltration.
Sequence Similarities: Belongs to the type I cytokine receptor family. Type 3 subfamily.
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分子量
- 13 kDa
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途径
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation
抗原
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