(7 references)-
- 抗原 See all MAPT 抗体
- MAPT (Microtubule-Associated Protein tau (MAPT))
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抗原表位
- AA 29-44, N-Term
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This MAPT antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 原理
- Rabbit IgG polyclonal antibody for Microtubule-associated protein tau(MAPT) detection. Tested with WB in Human,Mouse,Rat.
- 序列
- YTMHQDQEGD TDAGLK
- 交叉反应 （详细）
- No cross reactivity with other proteins.
- 产品特性
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Rabbit IgG polyclonal antibody for Microtubule-associated protein tau(MAPT) detection. Tested with WB in Human,Mouse,Rat.
Gene Name: microtubule-associated protein tau
Protein Name: Microtubule-associated protein tau - 纯化方法
- Immunogen affinity purified.
- 免疫原
- A synthetic peptide corresponding to a sequence at the N-terminus of human Tau(29-44aa YTMHQDQEGDTDAGLK), different from the related mouse and rat sequences by three amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product MAPT Primary Antibody
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anti-Microtubule-Associated Protein tau (MAPT) (pThr212) antibody
MAPT 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Microtubule-Associated Protein tau (MAPT) (pSer235) antibodyMAPT 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Microtubule-Associated Protein tau (MAPT) (pSer262) antibodyMAPT 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Microtubule-Associated Protein tau (MAPT) (AA 1-100) antibodyMAPT 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Microtubule-Associated Protein tau (MAPT) (pThr205) antibodyMAPT 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Microtubule-Associated Protein tau (MAPT) (pThr181) antibodyMAPT 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Microtubule-Associated Protein tau (MAPT) (pSer404) antibodyMAPT 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Microtubule-Associated Protein tau (MAPT) (pSer404) antibodyMAPT 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Microtubule-Associated Protein tau (MAPT) (pSer396) antibodyMAPT 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Microtubule-Associated Protein tau (MAPT) (pSer422) antibodyMAPT 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Mouse, Rat
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities.
Other applications have not been tested. Optimal dilutions should be determined by end users. - 说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- 浓度
- 500 μg/mL
- 缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
- 储存液
- Thimerosal (Merthiolate), Sodium azide
- 注意事项
- This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
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At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing. - 有效期
- 12 months
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: "Lychee seed extract protects against neuronal injury and improves cognitive function in rats with type II diabetes mellitus with cognitive impairment." in: International journal of molecular medicine, Vol. 41, Issue 1, pp. 251-263, (2018) (PubMed).
: "The expression of insulin-like growth factor-1 in senior patients with diabetes and dementia." in: Experimental and therapeutic medicine, Vol. 13, Issue 1, pp. 103-106, (2017) (PubMed).
: "Allicin improves endoplasmic reticulum stress-related cognitive deficits via PERK/Nrf2 antioxidative signaling pathway." in: European journal of pharmacology, Vol. 762, pp. 239-46, (2015) (PubMed).
: "Cellular and molecular mechanisms underlying the action of ginsenoside Rg1 against Alzheimer's disease." in: Neural regeneration research, Vol. 7, Issue 36, pp. 2860-6, (2014) (PubMed).
: "Effects of surface charges of graphene oxide on neuronal outgrowth and branching." in: The Analyst, Vol. 139, Issue 1, pp. 105-15, (2013) (PubMed).
: "Panax notoginsenoside Rb1 ameliorates Alzheimer's disease by upregulating brain-derived neurotrophic factor and downregulating Tau protein expression." in: Experimental and therapeutic medicine, Vol. 6, Issue 3, pp. 826-830, (2013) (PubMed).
: "Protective effects of lithium treatment for spatial memory deficits induced by tau hyperphosphorylation in splenectomized rats." in: Clinical and experimental pharmacology & physiology, Vol. 37, Issue 10, pp. 1010-5, (2010) (PubMed).
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: "Lychee seed extract protects against neuronal injury and improves cognitive function in rats with type II diabetes mellitus with cognitive impairment." in: International journal of molecular medicine, Vol. 41, Issue 1, pp. 251-263, (2018) (PubMed).
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- 抗原
- MAPT (Microtubule-Associated Protein tau (MAPT))
- 别名
- MAPT (MAPT 产品)
- 别名
- DDPAC antibody, FTDP-17 antibody, MAPTL antibody, MSTD antibody, MTBT1 antibody, MTBT2 antibody, PPND antibody, TAU antibody, AI413597 antibody, AW045860 antibody, Mtapt antibody, Tau antibody, RNPTAU antibody, pTau antibody, tau antibody, xtp antibody, MAPT antibody, PHF-tau antibody, slc6a6 antibody, taut antibody, wu:fc26e12 antibody, microtubule associated protein tau antibody, microtubule-associated protein tau antibody, microtubule associated protein tau S homeolog antibody, Microtubule-associated protein tau antibody, solute carrier family 6 (neurotransmitter transporter), member 6b antibody, MAPT antibody, Mapt antibody, mapt.S antibody, LOC5580230 antibody, CpipJ_CPIJ013260 antibody, tau antibody, slc6a6b antibody
- 背景
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MAPT, Microtubule-associated protein tau, appears to be enriched in axons. The MAPT gene is assigned to chromosome 17 by hybridization of a cDNA clone to flow-sorted and spot-blotted chromosomes and to 17q21 by in situ hybridization, containing 16 exons. The tau proteins are the product of alternative splicingfrom a single gene that in humans is designated MAPT. Tau proteins are proteins that stabilize microtubules. They are abundant in neurons in the central nervous system and are less common elsewhere. When tau proteins are defective, and no longer stabilize microtubules properly, they can result in dementias such as Alzheimer's disease.
Synonyms: AI413597 antibody|AW045860 antibody|DDPAC antibody|Disinhibition dementia parkinsonism amyotrophy complex antibody|FLJ31424 antibody|FTDP 17 antibody|FTDP17 antibody|G Protein beta 1 gamma 2 subunit interacting factor 1 antibody|G protein beta1/gamma2 subunit interacting factor 1 antibody|MAPT antibody|MAPTL antibody|MGC134287 antibody|MGC138549 antibody|MGC156663 antibody|Microtubule associated protein tau antibody|Microtubule associated protein tau isoform 4 antibody|Microtubule associated protein tau, isoform 4 antibody|Microtubule-associated protein tau antibody|MSTD antibody|MTAPT antibody|MTBT 1 antibody|MTBT 2 antibody|MTBT1 antibody|MTBT2 antibody|Neurofibrillary tangle protein antibody|Paired helical filament tau antibody|Paired helical filament-tau antibody|PHF tau antibody|PHF-tau antibody|PPND antibody|pTau antibody|RNPTAU antibody|TAU antibody|TAU_HUMAN antibody|Tauopathy and respiratory failure, included antibody - UniProt
- P10636
- 途径
- MAPK Pathway, Microtubule Dynamics, M Phase, Regulation of Cell Size
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