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IDO2 抗体 (N-Term)

IDO2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3043149
发货至: 中国
  • 抗原 See all IDO2 抗体
    IDO2 (Indoleamine 2,3-Dioxygenase 2 (IDO2))
    抗原表位
    • 8
    • 5
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-20, N-Term
    适用
    • 40
    • 7
    • 6
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    宿主
    • 37
    • 7
    • 1
    克隆类型
    • 38
    • 7
    多克隆
    标记
    • 25
    • 4
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This IDO2 antibody is un-conjugated
    应用范围
    • 34
    • 20
    • 13
    • 6
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    原理
    Anti-INDOL1/IDO2 Antibody Picoband®
    序列
    MLHFHYYDTS NKIMEPHRPN
    交叉反应 (详细)
    No cross-reactivity with other proteins
    产品特性
    Anti-INDOL1/IDO2 Antibody (ABIN3043149). Tested in WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
    纯化方法
    Immunogen affinity purified.
    免疫原
    A synthetic peptide corresponding to a sequence at the N-terminus of human INDOL1.
    亚型
    IgG
    Top Product
    Discover our top product IDO2 Primary Antibody
  • 应用备注
    Western blot, 0.1-0.5 μg/mL, Human
    1. Ball, H. J., Sanchez-Perez, A., Weiser, S., Austin, C. J. D., Astelbauer, F., Miu, J., McQuillan, J. A., Stocker, R., Jermin, L. S., Hunt, N. H. Characterization of an indoleamine 2,3-dioxygenase-like protein found in humans and mice. Gene 396: 203-213, 2007. 2. Metz, R., DuHadaway, J. B., Kamasani, U., Laury-Kleintop, L., Muller, A. J., Prendergast, G. C. Novel tryptophan catabolic enzyme IDO2 is the preferred biochemical target of the antitumor indoleamine 2,3-dioxygenase inhibitory compound D-1-methyl-tryptophan. Cancer Res. 67: 7082-7087, 2007.
    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    浓度
    500 μg/mL
    缓冲液
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.01 mg Thimerosal, 0.01 mg Sodium azide.
    储存液
    Thimerosal (Merthiolate), Sodium azide
    注意事项
    This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C,-20 °C
    储存方法
    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    IDO2 (Indoleamine 2,3-Dioxygenase 2 (IDO2))
    别名
    IDO2 (IDO2 产品)
    背景

    Synonyms: Indoleamine 2,3-dioxygenase 2,IDO-2,1.13.11.-,Indoleamine 2,3-dioxygenase-like protein 1,Indoleamine-pyrrole 2,3-dioxygenase-like protein 1,IDO2,INDOL1,

    Tissue Specificity: Detected in liver, small intestine, spleen, placenta, thymus, lung, brain, kidney, and colon. .

    Background: IDO2 (Indoleamine 2,3-dioxygenase 2), also called INDOLEAMINE 2,3-DIOXYGENASE-LIKE 1 or INDOL1, is an enzyme encoded by the INDOL1 gene which metabolizes tryptophan in the kynurenine pathway. By genomic sequence analysis, the INDOL1 gene is mapped on chromosome 8p12 just downstream of the INDO gene. And its exact cytogenetic location is 8p11.21. By database analysis using INDO as probe, followed by RT-PCR of total RNA from various tissues, IDO2 is cloned by human and mouse INDOL1. INDOL1 catabolizes tryptophan as determined by Kyn production, but unlike INDO, is inhibited by D-1-methyl-tryptophan (D-1MT) but not the L-1MT stereoisomer. The Gene Structure of the INDOL1 has 11 exons and spans 74 kb.

    Sequence Similarities: Belongs to the indoleamine 2,3-dioxygenase family.

    分子量
    47 kDa
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