Kallikrein 5 抗体 (C-Term)
Quick Overview for Kallikrein 5 抗体 (C-Term) (ABIN3043138)
抗原
See all Kallikrein 5 (KLK5) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 278-293, C-Term
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原理
- Anti-Kallikrein 5/KLK5 Antibody Picoband®
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序列
- NLCEFVKWIK DTMNSN
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交叉反应 （详细）
- No cross-reactivity with other proteins
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产品特性
- Anti-Kallikrein 5/KLK5 Antibody (ABIN3043138). Tested in IHC, WB applications. This antibody reacts with Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the C-terminus of mouse Kallikrein 5, different from the related rat sequence by three amino acids.
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亚型
- IgG
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anti-Kallikrein 5 (KLK5) (AA 25-261) antibody
KLK5 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Kallikrein 5 (KLK5) (AA 23-293) antibodyKLK5 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Kallikrein 5 (KLK5) (Internal Region) antibodyVerified KLK5 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Kallikrein 5 (KLK5) antibodyKLK5 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Kallikrein 5 (KLK5) (AA 144-174) antibodyKLK5 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB6112 unconjugated
anti-Kallikrein 5 (KLK5) (AA 194-293) antibodyKLK5 适用: 人 ELISA 宿主: 小鼠 Monoclonal 3H3 unconjugated
anti-Kallikrein 5 (KLK5) (AA 1-293) antibodyKLK5 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Kallikrein 5 (KLK5) (AA 35-84) antibodyKLK5 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Kallikrein 5 (KLK5) (N-Term) antibodyKLK5 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Rat, Mouse
Western blot, 0.1-0.5 μg/mL, Mouse
1. Brattsand, M., Egelrud, T. Purification, molecular cloning, and expression of a human stratum corneum trypsin-like serine protease with possible function in desquamation. J. Biol. Chem. 274: 30033-30040, 1999. 2. Elliott, M. B., Irwin, D. M., Diamandis, E. P. In silico identification and Bayesian phylogenetic analysis of multiple new mammalian kallikrein gene families. Genomics 88: 591-599, 2006. 3. Gan, L., Lee, I., Smith, R., Argonza-Barrett, R., Lei, H., McCuaig, J., Moss, P., Paeper, B., Wang, K. Sequencing and expression analysis of the serine protease gene cluster located in chromosome 19q13 region. Gene 257: 119-130, 2000. -
说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
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储存液
- Thimerosal (Merthiolate), Sodium azide
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注意事项
- This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles. -
有效期
- 12 months
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- Kallikrein 5 (KLK5)
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别名
- KLK5
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背景
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Synonyms: Kallikrein 1-related peptidase b5 ,Kallikrein related-peptidase 5 ,Klk5 ,
Tissue Specificity: Isoform beta-3A and isoform beta-3C are widely expressed. Isoform beta-3A is specifically expressed in osteoblast cells, isoform beta-3C is specifically expressed in prostate and testis.
Background: KLK5 (Kallikrein-related peptidase 5), formerly known as stratum corneum tryptic enzyme (SCTE) or KLKL2, is a serine protease expressed in the epidermis. The KLK5 gene is one of the fifteen kallikrein subfamily members which is located on 19q13.41. KLK5 has been suggested to regulate cell shedding in conjunction with KLK7 and KLK14, given its ability to degrade proteins which form the extracellular component of cell junctions in the stratum corneum. The KLK5 gene contains 5 coding exons spanning 9.3. KLK5 expression is upregulated in a breast cancer cell line in the presence of estrogens and progestins and is associated with more aggressive forms of epithelial ovarian carcinoma.
Sequence Similarities: Belongs to the integrin beta chain family.
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分子量
- 29 kDa
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UniProt
- Q9D140
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途径
- Complement System, Regulation of G-Protein Coupled Receptor Protein Signaling
抗原
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