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Kallikrein 11 抗体 (C-Term)

KLK11 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3043137
发货至: 中国
  • 抗原 See all Kallikrein 11 (KLK11) 抗体
    Kallikrein 11 (KLK11)
    抗原表位
    • 14
    • 6
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 233-250, C-Term
    适用
    • 46
    • 3
    • 2
    • 1
    宿主
    • 42
    • 3
    • 1
    克隆类型
    • 45
    • 1
    多克隆
    标记
    • 19
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Kallikrein 11 antibody is un-conjugated
    应用范围
    • 29
    • 12
    • 12
    • 10
    • 9
    • 6
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    Western Blotting (WB), Immunohistochemistry (IHC)
    原理
    Anti-Kallikrein 11/KLK11 Antibody Picoband®
    序列
    YTKVCKYVDW IQETMKNN
    交叉反应 (详细)
    No cross-reactivity with other proteins
    产品特性
    Anti-Kallikrein 11/KLK11 Antibody (ABIN3043137). Tested in IHC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
    纯化方法
    Immunogen affinity purified.
    免疫原
    A synthetic peptide corresponding to a sequence at the C-terminus of human Kallikrein 11.
    亚型
    IgG
    Top Product
    Discover our top product KLK11 Primary Antibody
  • 应用备注
    Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human
    Western blot, 0.1-0.5 μg/mL, Human
    1. Elliott, M. B., Irwin, D. M., Diamandis, E. P. In silico identification and Bayesian phylogenetic analysis of multiple new mammalian kallikrein gene families. Genomics 88: 591-599, 2006. 2. Gan, L., Lee, I., Smith, R., Argonza-Barrett, R., Lei, H., McCuaig, J., Moss, P., Paeper, B., Wang, K. Sequencing and expression analysis of the serine protease gene cluster located in chromosome 19q13 region. Gene 257: 119-130, 2000. 3. Yoshida S, Taniguchi M, Suemoto T, Oka T, He X, Shiosaka S (Oct 1998). "cDNA cloning and expression of a novel serine protease, TLSP".
    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    浓度
    500 μg/mL
    缓冲液
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
    储存液
    Thimerosal (Merthiolate), Sodium azide
    注意事项
    This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C,-20 °C
    储存方法
    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
    有效期
    12 months
  • Gao, Wang, Yan, Zeng, Ma, Niu, Zhou, Jiang, Chen: "Comparative Transcriptome Analysis of Fetal Skin Reveals Key Genes Related to Hair Follicle Morphogenesis in Cashmere Goats." in: PLoS ONE, Vol. 11, Issue 3, pp. e0151118, (2016) (PubMed).

  • 抗原
    Kallikrein 11 (KLK11)
    别名
    KLK11 (KLK11 产品)
    背景

    Synonyms: Kallikrein-11,hK11,3.4.21.-,Hippostasin,Serine protease 20,Trypsin-like protease,Kallikrein-11 inactive chain 1,Kallikrein-11 inactive chain 2,KLK11,PRSS20, TLSP,UNQ649/PRO1279,

    Tissue Specificity: Expressed in brain, skin and prostate. Isoform 1 is expressed preferentially in brain. Isoform 2 is expressed in prostate. Present in seminal plasma at concentrations ranging from 2 to 37 microg/mL (at protein level). .

    Background: KLK11 (KALLIKREIN 11), also called PRSS20 or TLSP, is a protein that in humans is encoded by the KLK11 gene. KLK11 is a member of the kallikrein subfamily of serine proteases, which are involved in a variety of enzymatic processes. The KLK11 gene is mapped to 19q13.41. The KLK11 gene contains 6 exons, the first of which is noncoding. KLK11 shares 48 % amino acid sequence identity with mouse neuropsin, 43 % identity with both human trypsin-1 and human kallikrein, and 38 % identity with the mouse nerve growth factor gamma subunit. Alternate splicing of the KLK11 gene results in two transcript variants encoding two different isoforms which are differentially expressed. Western blot analysis of recombinant KLK11 suggested that the protein is secreted and posttranslationally processed.

    Sequence Similarities: Belongs to the peptidase S1 family. Kallikrein subfamily.

    分子量
    31 kDa
    途径
    Complement System
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