IL-13 抗体 (C-Term)
Quick Overview for IL-13 抗体 (C-Term) (ABIN3043089)
抗原
See all IL-13 (IL13) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 135-146, C-Term
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原理
- Anti-Interleukin-13 IL13 Antibody Picoband®
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序列
- HLKKLFREGR FN
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交叉反应 (详细)
- No cross-reactivity with other proteins
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产品特性
- < a href="https://www.bosterbio.com/anti-il-13-antibody-pa1469-boster.html" style="color:#EA8D28">Anti-Interleukin-13 IL13 Antibody (ABIN3043089). Tested in WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the C-terminus of human IL-13.
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亚型
- IgG
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应用备注
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Western blot, 0.1-0.5 μg/mL, Human
1. Blackburn, M. R., Lee, C. G., Young, H. W. J., Zhu, Z., Chunn, J. L., Kang, M. J., Banerjee, S. K., Elias, J. A.Adenosine mediates IL-13-induced inflammation and remodeling in the lung and interacts in an IL-13-adenosine amplification pathway. 2. Paul, W. E.Personal Communication.Bethesda, Md. 3/6/1993. 3. Punnonen, J., Aversa, G., Cocks, B. G., McKenzie, A. N. J., Menon, S., Zurawski, G., de Waal Malefyt, R., de Vries, J. E.Interleukin 13 induces interleukin 4-independent IgG4 and IgE synthesis and CD23 expression by human B cells.Proc. Nat. Acad. Sci. 90: 3730-3734, 1993. -
说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
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储存液
- Thimerosal (Merthiolate), Sodium azide
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注意事项
- This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles. -
有效期
- 12 months
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: "Number 2 Feibi Recipe Reduces PM2.5-Induced Lung Injury in Rats." in: Evidence-based complementary and alternative medicine : eCAM, Vol. 2018, pp. 3674145, (2018) (PubMed).
: "Acute exposure of ozone induced pulmonary injury and the protective role of vitamin E through the Nrf2 pathway in Balb/c mice." in: Toxicology research, Vol. 5, Issue 1, pp. 268-277, (2018) (PubMed).
: "CD68 and interleukin 13, prospective immune markers for esophageal squamous cell carcinoma prognosis prediction." in: Oncotarget, Vol. 7, Issue 13, pp. 15525-38, (2017) (PubMed).
: "Th17 down-regulation is involved in reduced progression of schistosomiasis fibrosis in ICOSL KO mice." in: PLoS neglected tropical diseases, Vol. 9, Issue 1, pp. e0003434, (2016) (PubMed).
: "An IL-13 promoter polymorphism associated with liver fibrosis in patients with Schistosoma japonicum." in: PLoS ONE, Vol. 10, Issue 8, pp. e0135360, (2016) (PubMed).
: "T-helper type-2 contact hypersensitivity of Balb/c mice aggravated by dibutyl phthalate via long-term dermal exposure." in: PLoS ONE, Vol. 9, Issue 2, pp. e87887, (2014) (PubMed).
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: "Number 2 Feibi Recipe Reduces PM2.5-Induced Lung Injury in Rats." in: Evidence-based complementary and alternative medicine : eCAM, Vol. 2018, pp. 3674145, (2018) (PubMed).
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- IL-13 (IL13) (Interleukin 13 (IL13))
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别名
- IL13
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背景
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Synonyms: Interleukin-13,IL-13,IL13,NC30,
Background: IL-13, Interleukin 13, is a protein that in humans is encoded by the IL-13 gene. IL-13 is cytokine secreted by many cell types, but especially T helper type 2 (Th2) cells, that is an important mediator of allergic inflammation and disease. The IL-13 gene is mapped to 5q23-q31. IL-13 induces its effects through a multi-subunit receptor that includes the alpha chain of the IL-4 receptor (IL-4Ralpha) and at least one of two known IL-13-specific binding chains. IL-13 acts more prominently as a molecular bridge linking allergic inflammatory cells to the non-immune cells in contact with them, thereby altering physiological function.
Sequence Similarities: Belongs to the IL-4/IL-13 family.
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分子量
- 58 kDa
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UniProt
- P35225
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途径
- JAK/STAT Signaling, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Proton Transport
抗原
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