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LAMP1 抗体 (C-Term)

This anti-LAMP1 antibody is a 兔 多克隆 antibody detecting LAMP1 in WB. Suitable for 人 和 小鼠.
产品编号 ABIN3043036
发货至: 中国

Quick Overview for LAMP1 抗体 (C-Term) (ABIN3043036)

抗原

See all LAMP1 抗体
LAMP1 (Lysosomal-Associated Membrane Protein 1 (LAMP1))

适用

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人, 小鼠

宿主

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克隆类型

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多克隆

标记

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This LAMP1 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    AA 403-417, C-Term

    原理

    Anti-LAMP1 Antibody Picoband®

    序列

    YLVGRKRSHA GYQTI

    交叉反应 (详细)

    No cross-reactivity with other proteins

    产品特性

    Anti-LAMP1 Antibody (ABIN3043036). Tested in WB applications. This antibody reacts with Human, Mouse. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence at the C-terminus of human LAMP1, different from the related mouse and rat sequences by one amino acid.

    亚型

    IgG
  • 应用备注

    Western blot, 0.1-0.5 μg/mL, Human, Mouse
    1. Bermingham, N. A., Martin, J. E., Fisher, E. M. C. The mouse lysosomal membrane protein 1 gene as a candidate for the motorneuron degeneration (mnd) locus. Genomics 32: 266-271, 1996. 2. Mattei, M.-G., Matterson, J., Chen, J. W., Williams, M. A., Fukuda, M. Two human lysosomal membrane glycoproteins, h-lamp-1 and h-lamp-2, are encoded by genes localized to chromosome 13q34 and chromosome Xq24-25, respectively. J. Biol. Chem. 265: 7548-7551, 1990. 3. Yogalingam, G., Bonten, E. J., van de Vlekkert, D., Hu, H., Moshiach, S., Connell, S. A., d'Azzo, A. Neuraminidase 1 is a negative regulator of lysosomal exocytosis. Dev. Cell 15: 74-86, 2008.

    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    LAMP1 (Lysosomal-Associated Membrane Protein 1 (LAMP1))

    别名

    LAMP1

    背景

    Synonyms: Lysosome-associated membrane glycoprotein 1;LAMP-1;Lysosome-associated membrane protein 1;CD107 antigen-like family member A;CD107a;LAMP1;

    Tissue Specificity: Expressed in breast, ovary and prostate.

    Background: LAMP1 (lysosomal-associated membrane protein 1) also called LAMPA, LGP120 or CD107A, is a member of a family of membrane glycoproteins. This glycoprotein provides selectins with carbohydrate ligands. It may also play a role in tumor cell metastasis. CD107a has also been shown to be a marker of degranulation on lymphocytes such as CD8+ and NK cells. By means of in situ hybridization, Mattei et al. (1990) assigned the LAMP1 gene to chromosome 13q34. A related gene, which may be a pseudogene, mapped to chromosome 12p13.3. Hybridization of LAMP1 cDNA to chromosome 12p13.3 was observed even when probes representing different portions of the LAMP1 cDNA were used.

    Sequence Similarities: Belongs to the peptidase S1 family. Kallikrein subfamily.

    分子量

    90-120 kDa (Glycosylation)

    UniProt

    P11279

    途径

    Autophagy
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