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NOTCH4 抗体 (C-Term)

NOTCH4 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3043028
发货至: 中国
  • 抗原 See all NOTCH4 抗体
    NOTCH4 (Notch 4 (NOTCH4))
    抗原表位
    • 15
    • 8
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1805-1818, C-Term
    适用
    • 39
    • 29
    • 20
    • 4
    • 4
    • 4
    • 3
    • 3
    • 1
    • 1
    宿主
    • 53
    • 3
    • 2
    克隆类型
    • 48
    • 10
    多克隆
    标记
    • 30
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This NOTCH4 antibody is un-conjugated
    应用范围
    • 27
    • 17
    • 13
    • 13
    • 6
    • 5
    • 5
    • 4
    • 2
    • 2
    Western Blotting (WB)
    原理
    Rabbit IgG polyclonal antibody for Neurogenic locus notch homolog protein 4(NOTCH4) detection. Tested with WB in Human.
    序列
    DVAHQRNHWD LLTL
    交叉反应 (详细)
    No cross reactivity with other proteins.
    产品特性
    Rabbit IgG polyclonal antibody for Neurogenic locus notch homolog protein 4(NOTCH4) detection. Tested with WB in Human.
    Gene Name: notch 4
    Protein Name: Neurogenic locus notch homolog protein 4(Notch 4)
    纯化方法
    Immunogen affinity purified.
    免疫原
    A synthetic peptide corresponding to a sequence at the C-terminus of human NOTCH4(1805-1818aa DVAHQRNHWDLLTL).
    亚型
    IgG
    Top Product
    Discover our top product NOTCH4 Primary Antibody
  • 应用备注
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human
    Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities.
    Other applications have not been tested. Optimal dilutions should be determined by end users.
    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    浓度
    500 μg/mL
    缓冲液
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
    储存液
    Thimerosal (Merthiolate), Sodium azide
    注意事项
    This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
    有效期
    12 months
  • 抗原
    NOTCH4 (Notch 4 (NOTCH4))
    别名
    NOTCH4 (NOTCH4 产品)
    别名
    INT3 antibody, NOTCH3 antibody, Int-3 antibody, Int3 antibody, N4 antibody, Notch4 antibody, notch 4 antibody, neurogenic locus notch homolog protein 4 antibody, NOTCH4 antibody, Notch4 antibody, LOC100712850 antibody
    背景
    NOTCH4(NOTCH, DROSOPHILA, HOMOLOG OF, 4) also known as INT3 or NOTCH3, FORMERLY, is a member of the Notch family. In situ hybridization revealed that Notch4 transcripts are primarily restricted to endothelial cells in embryonic and adult life, suggesting a specific role forNotch4 during development of vertebrate endothelium. The sequences of the mouse and human NOTCH4 proteins are 82 % identical. Northern blot analysis revealed that NOTCH4(S) is the major transcript and is expressed in a wide variety of tissues. Fluorescence in situ hybridization confirmed the location of the NOTCH4 gene at chromosome 6p21.3. In linkage disequilibrium mapping of the MHC region in 80 British parent-offspring trios, Wei and Hemmings(2000) found that NOTCH4 was highly associated with schizophrenia. Repression of Notch4 resolved ataxia and reversed the disease progression, demonstrating that Notch4 is not only sufficient to induce but also required to sustain the disease.

    Synonyms: FLJ16302 antibody|hNotch 4 antibody|hNotch4 antibody|INT3 antibody|Neurogenic locus notch homolog protein 4 antibody|NOTC4_HUMAN antibody|Notch 4 antibody|Notch 4 intracellular domain antibody|Notch homolog 4 antibody|NOTCH3 antibody|Notch4 antibody|NOTCH4 protein antibody
    UniProt
    Q99466
    途径
    Notch Signaling
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