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CXCR2 抗体 (Middle Region)

Name: CXCR2 抗体 (Middle Region)
SKU: ABIN3043018
Availability: OutOfStock

This 兔多克隆 antibody specifically detects CXCR2 in WB. It exhibits reactivity toward 人和大鼠. It has been mentioned in 5+ publications

Western blot analysis of CXCR2 using anti-CXCR2 antibody (ABIN3043018). (CXCR2 抗体 (Middle Region))

Western Blotting (WB) image for anti-Chemokine (C-X-C Motif) Receptor 2 (CXCR2) (Middle Region) antibody (ABIN3043018) (CXCR2 抗体 (Middle Region))

Anti-CXCR2 antibody, Western blotting Lane 1: Human Rectal Cancer Tissue Lysate Lane 2: Human Rectal Cancer Tissue Lysate (CXCR2 抗体 (Middle Region))

3 images

(5 references)

产品编号 ABIN3043018

发货至: 中国

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中国
北京 101111

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Quick Overview for CXCR2 抗体 (Middle Region) (ABIN3043018)

抗原

See all CXCR2 抗体

CXCR2 (Chemokine (C-X-C Motif) Receptor 2 (CXCR2))

适用

人, 大鼠

宿主

兔

克隆类型

多克隆

标记

This CXCR2 antibody is un-conjugated

应用范围

Western Blotting (WB)

Discover our top product CXCR2 Primary Antibody

抗原表位
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Middle Region

原理

Anti-CXCR2 Antibody

序列

CYEDMGNNTA NWRMLLR

特异性

No cross reactivity with other proteins.

交叉反应（详细）

No cross-reactivity with other proteins

预测反应

different from the related mouse sequence by six amino acids.

产品特性

Anti-CXCR2 Antibody. Tested in WB applications. This antibody reacts with Human, Rat.

纯化方法

Immunogen affinity purified.

免疫原

A synthetic peptide corresponding to a sequence in the middle region of human CXCR2, different from the related mouse sequence by six amino acids.

亚型

IgG
anti-Chemokine (C-X-C Motif) Receptor 2 (CXCR2) antibody
CXCR2 适用: 人 IHC, ELISA, ICC, FACS 宿主: 小鼠 Monoclonal 5F7A11 unconjugated

anti-Chemokine (C-X-C Motif) Receptor 2 (CXCR2) (AA 316-360) antibody
CXCR2 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated

anti-Chemokine (C-X-C Motif) Receptor 2 (CXCR2) (pSer347) antibody
CXCR2 适用: 人, 小鼠 WB, IHC, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated

anti-Chemokine (C-X-C Motif) Receptor 2 (CXCR2) antibody
CXCR2 适用: 人 IHC, ELISA, FACS 宿主: 小鼠 Monoclonal 7E9H12 unconjugated

anti-Chemokine (C-X-C Motif) Receptor 2 (CXCR2) (AA 1-40) antibody
CXCR2 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated

anti-Chemokine (C-X-C Motif) Receptor 2 (CXCR2) (N-Term) antibody
CXCR2 适用: 人 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Chemokine (C-X-C Motif) Receptor 2 (CXCR2) (AA 32-54) antibody
CXCR2 适用: 人 WB, IHC, ELISA, FACS 宿主: 兔 Polyclonal unconjugated

anti-Chemokine (C-X-C Motif) Receptor 2 (CXCR2) (AA 1-57) antibody
CXCR2 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Chemokine (C-X-C Motif) Receptor 2 (CXCR2) (C-Term) antibody
CXCR2 适用: 人, 小鼠, 大鼠 WB, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated

anti-Chemokine (C-X-C Motif) Receptor 2 (CXCR2) (Extracellular Domain) antibody
CXCR2 适用: 人, 猴 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated

应用备注

Western blot, 0.1-0.5 μg/mL, Human, Rat

说明

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

限制

仅限研究用
状态

Lyophilized

溶解方式

Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

浓度

500 μg/mL

缓冲液

Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

注意事项

Avoid repeated freezing and thawing.

储存条件

4 °C,-20 °C

储存方法

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

有效期

12 months
Zhou, Li, Li, Liu, Zhu, Ju, Miao, Xu: "Overexpression of GRK6 attenuates neuropathic pain via suppression of CXCR2 in rat dorsal root ganglion." in: Molecular pain, Vol. 12, (2016) (PubMed).

Xu, Zhu, Zhang, Tian, Zhang, Wu, Gao: "NF?B-mediated CXCL1 production in spinal cord astrocytes contributes to the maintenance of bone cancer pain in mice." in: Journal of neuroinflammation, Vol. 11, pp. 38, (2014) (PubMed).

Cao, Zhang, Xie, Jiang, Ji, Gao: "Chemokine CXCL1 enhances inflammatory pain and increases NMDA receptor activity and COX-2 expression in spinal cord neurons via activation of CXCR2." in: Experimental neurology, Vol. 261, pp. 328-36, (2014) (PubMed).

Chen, Park, Xie, Berta, Nedergaard, Ji: "Connexin-43 induces chemokine release from spinal cord astrocytes to maintain late-phase neuropathic pain in mice." in: Brain : a journal of neurology, Vol. 137, Issue Pt 8, pp. 2193-209, (2014) (PubMed).

Zhang, Cao, Zhang, Ji, Gao: "Chemokine contribution to neuropathic pain: respective induction of CXCL1 and CXCR2 in spinal cord astrocytes and neurons." in: Pain, Vol. 154, Issue 10, pp. 2185-97, (2013) (PubMed).
抗原

CXCR2 (Chemokine (C-X-C Motif) Receptor 2 (CXCR2))

别名

CXCR2

背景

Background: CXCR2 is a receptor for Interleukin 8, which is a powerful neutrophil chemotactic factor. It is a member of the GPCR family (subfamily, chemokine). Binding of IL8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activate a phosphatidylinositol-calcium second messenger system. This receptor binds to IL8 with a high affinity and to GRO/MGSA and NAP2 also with a high affinity. It has been reported to be expressed in a wide variety of tissues. ESTs have been isolated from human placenta and thymus libraries.
Gene Full Name: C-X-C motif chemokine receptor 2
Sequence Similarities: Belongs to the G-protein coupled receptor 1 family.

分子量

45 kDa

基因ID

3579

UniProt

P25025

途径

cAMP Metabolic Process