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Cullin 2 抗体 (Middle Region)

This 兔 多克隆 antibody specifically detects Cullin 2 in WB. It exhibits reactivity toward 人, 小鼠 和 大鼠.
产品编号 ABIN3043009
发货至: 中国
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Quick Overview for Cullin 2 抗体 (Middle Region) (ABIN3043009)

抗原

See all Cullin 2 (CUL2) 抗体
Cullin 2 (CUL2)

适用

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人, 小鼠, 大鼠

宿主

  • 82
  • 2
  • 1

克隆类型

  • 63
  • 22
多克隆

标记

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  • 6
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This Cullin 2 antibody is un-conjugated

应用范围

  • 48
  • 27
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  • 3
  • 1
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Western Blotting (WB)
  • 抗原表位

    • 15
    • 9
    • 8
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    AA 264-280, Middle Region

    原理

    Anti-Cullin 2/CUL2 Antibody

    序列

    HECQQRMVAD HLQFLHA

    交叉反应 (详细)

    No cross-reactivity with other proteins

    产品特性

    Anti-Cullin 2/CUL2 Antibody (ABIN3043009). Tested in WB applications. This antibody reacts with Human, Mouse, Rat. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence in the middle region of human Cullin 2, different from the related mouse and rat sequences by one amino acid.

    亚型

    IgG
  • 应用备注

    Western blot, 0.1-0.5 μg/mL, Human, Rat, Mouse

    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

    储存液

    Thimerosal (Merthiolate), Sodium azide

    注意事项

    This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    Cullin 2 (CUL2)

    别名

    CUL2

    背景

    Synonyms: Cullin-2,CUL-2,CUL2,

    Background: Cullin 2 (CUL2) is a protein that in humans is encoded by the CUL2 gene. Using immunofluorescence, they showed that CUL2 is a cytosolic protein that can be translocated to the nucleus by VHL. By fluorescence in situ hybridization, Clifford et al. (1999)mapped the CUL2 gene to 10p11.2-p11.1, a region reported to show loss of heterozygosity (LOH) in several forms of human cancer, including non-clear cell renal cell carcinoma. Pause et al. (1997)suggested that CUL2 is a candidate tumor suppressor gene, as has been proposed for CUL1 (603134). Lonergan et al. (1998) demonstrated that formation of the VBC-CUL2 complexes is linked to the regulation of hypoxia-inducible mRNAs by VHL. Cul2 was one of several proteins required for degradation of a class of RNA-binding germline proteins in somatic cells of the early blastomere.

    分子量

    37 kDa

    UniProt

    Q13617

    途径

    M Phase, Asymmetric Protein Localization, SARS-CoV-2 Protein Interactome
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