KLF8 抗体 (N-Term)
Quick Overview for KLF8 抗体 (N-Term) (ABIN3043005)
抗原
See all KLF8 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-18, N-Term
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原理
- Anti-Krueppel-like factor 8 KLF8 Antibody Picoband®
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序列
- MVDMDKLINN LEVQLNSE
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交叉反应 （详细）
- No cross-reactivity with other proteins
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产品特性
- Anti-Krueppel-like factor 8 KLF8 Antibody (ABIN3043005). Tested in WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the N-terminus of human KLF8.
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亚型
- IgG
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anti-Kruppel-Like Factor 8 (KLF8) (AA 1-359) antibody
KLF8 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Kruppel-Like Factor 8 (KLF8) (AA 1-98) antibodyKLF8 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2E10 unconjugated
anti-Kruppel-Like Factor 8 (KLF8) (AA 1-359) antibodyKLF8 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Kruppel-Like Factor 8 (KLF8) (AA 210-280) antibodyKLF8 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Kruppel-Like Factor 8 (KLF8) (N-Term) antibodyVerified KLF8 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Kruppel-Like Factor 8 (KLF8) (AA 89-138) antibodyKLF8 适用: 人, 兔, Cow WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Kruppel-Like Factor 8 (KLF8) (N-Term) antibodyKLF8 适用: 人, 兔, 犬, 马, Cow WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Kruppel-Like Factor 8 (KLF8) (AA 74-123) antibodyKLF8 适用: 人, 豚鼠, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Kruppel-Like Factor 8 (KLF8) (AA 226-275) antibodyKLF8 适用: 人, 豚鼠, 犬 WB 宿主: 兔 Polyclonal unconjugated
anti-Kruppel-Like Factor 8 (KLF8) (Middle Region) antibodyKLF8 适用: 人, 兔, 豚鼠, 小鼠, 犬, 马, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.1-0.5 μg/mL, Human
1. Lossi, A.-M., Laugier-Anfossi, F., Depetris, D., Gecz, J., Gedeon, A., Kooy, F., Schwartz, C., Mattei, M.-G., Croquette, M.-F., Villard, L.Abnormal expression of the KLF8 (ZNF741) gene in a female patient with an X,autosome translocation t(X,21)(p11.2,q22.3) and non-syndromic mental retardation.J. Med. Genet. 39: 113-117, 2002. 2. Suske, G., Bruford, E., Philipsen, S.Mammalian SP/KLF transcription factors: bring in the family.Genomics 85: 551-556, 2005. 3. van Vliet, J., Turner, J., Crossley, M.Human Kruppel-like factor 8: a CACCC-box binding protein that associates with CtBP and represses transcription.Nucleic Acids Res. 28: 1955-1962, 2000. -
说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
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储存液
- Thimerosal (Merthiolate), Sodium azide
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注意事项
- This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles. -
有效期
- 12 months
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- KLF8 (Kruppel-Like Factor 8 (KLF8))
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别名
- KLF8
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背景
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Synonyms: Krueppel-like factor 8,Basic krueppel-like factor 3,Zinc finger protein 741,KLF8,BKLF3, ZNF741,
Tissue Specificity: Ubiquitous. .
Background: KLF8 (Krueppel-like factor 8) is a protein that in humans is encoded by the KLF8 gene. It is also named as ZNF741, or BKLF3. Kruppel-like factor proteins, including KLF8, all contain a characteristic C-terminal DNA-binding domain containing 3 Kruppel-like zinc fingers, and they all recognize CACCC and GC boxes present in promoters and enhancers. The International Radiation Hybrid Mapping Consortium mapped the KLF8 gene to the X chromosome (WI-18614). Suske et al. (2005) stated that the human KLF8 gene maps to chromosome Xp11.21, and the mouse Klf8 gene to chromosome XF3. van Vliet et al. (2000) identified a cDNA encoding KLF8, also called ZNF741. Expression of KLF8 or only its zinc fingers showed that the fingers could bind to a CACCC box. Sequence analysis predicted that the 359-amino acid protein contains a nuclear localization signal upstream of the zinc fingers, a valine-rich hydrophobic stretch, and a pro-val-asp-leu-ser (PVDLS) motif. Yeast 2-hybrid and GST pull-down analysis demonstrated that CTBP2 interacts with KLF8 through the PVDLS motif.
Sequence Similarities: Belongs to the Sp1 C2H2-type zinc-finger protein family.
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分子量
- 60 kDa
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UniProt
- O95600
抗原
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