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KLF8 抗体 (N-Term)

The 兔 多克隆 anti-KLF8 antibody (ABIN3043005) specifically detects KLF8 in WB. The antibody is reactive with 人 samples.
产品编号 ABIN3043005
发货至: 中国
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Quick Overview for KLF8 抗体 (N-Term) (ABIN3043005)

抗原

See all KLF8 抗体
KLF8 (Kruppel-Like Factor 8 (KLF8))

适用

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宿主

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克隆类型

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多克隆

标记

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This KLF8 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    AA 1-18, N-Term

    原理

    Anti-Krueppel-like factor 8 KLF8 Antibody

    序列

    MVDMDKLINN LEVQLNSE

    交叉反应 (详细)

    No cross-reactivity with other proteins

    产品特性

    Anti-Krueppel-like factor 8 KLF8 Antibody (ABIN3043005). Tested in WB applications. This antibody reacts with Human. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence at the N-terminus of human KLF8.

    亚型

    IgG
  • 应用备注

    Western blot, 0.1-0.5 μg/mL, Human

    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

    储存液

    Thimerosal (Merthiolate), Sodium azide

    注意事项

    This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    KLF8 (Kruppel-Like Factor 8 (KLF8))

    别名

    KLF8

    背景

    Synonyms: Krueppel-like factor 8,Basic krueppel-like factor 3,Zinc finger protein 741,KLF8,BKLF3, ZNF741,

    Tissue Specificity: Ubiquitous. .

    Background: KLF8 (Krueppel-like factor 8) is a protein that in humans is encoded by the KLF8 gene. It is also named as ZNF741, or BKLF3. Kruppel-like factor proteins, including KLF8, all contain a characteristic C-terminal DNA-binding domain containing 3 Kruppel-like zinc fingers, and they all recognize CACCC and GC boxes present in promoters and enhancers. The International Radiation Hybrid Mapping Consortium mapped the KLF8 gene to the X chromosome (WI-18614). Suske et al. (2005) stated that the human KLF8 gene maps to chromosome Xp11.21, and the mouse Klf8 gene to chromosome XF3. van Vliet et al. (2000) identified a cDNA encoding KLF8, also called ZNF741. Expression of KLF8 or only its zinc fingers showed that the fingers could bind to a CACCC box. Sequence analysis predicted that the 359-amino acid protein contains a nuclear localization signal upstream of the zinc fingers, a valine-rich hydrophobic stretch, and a pro-val-asp-leu-ser (PVDLS) motif. Yeast 2-hybrid and GST pull-down analysis demonstrated that CTBP2 interacts with KLF8 through the PVDLS motif.

    Sequence Similarities: Belongs to the Sp1 C2H2-type zinc-finger protein family.

    分子量

    60 kDa

    UniProt

    O95600
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