KLF8 抗体 (N-Term)
Our Local Distributor
北京 101111
Quick Overview for KLF8 抗体 (N-Term) (ABIN2777342)
抗原
See all KLF8 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- N-Term
-
原理
- KLF8 Antibody - N-terminal region
-
序列
- LSFHKPKAPL QPASMLQAPI RPPKPQSSPQ TLVVSTSTSD MSTSANIPTV
-
预测反应
- Cow: 79%, Dog: 79%, Horse: 77%, Human: 100%, Rabbit: 86%
-
产品特性
- This is a rabbit polyclonal antibody against KLF8. It was validated on Western Blot and immunohistochemistry.
-
纯化方法
- Affinity Purified
-
免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human KLF8
-
-
-
-
应用备注
- Optimal working dilution should be determined by the investigator.
-
说明
-
We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8104065
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 0.5 mg/mL
-
缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- prevent freeze-thaw cycles
-
储存条件
- 4 °C,-20 °C
-
储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
-
-
-
: "KLF8 promotes tumorigenesis, invasion and metastasis of colorectal cancer cells by transcriptional activation of FHL2." in: Oncotarget, Vol. 6, Issue 28, pp. 25402-17, (2015) (PubMed).
: "Krüppel?like factor expression and correlation with FAK, MMP?9 and E?cadherin expression in hepatocellular carcinoma." in: Molecular medicine reports, Vol. 8, Issue 1, pp. 81-8, (2013) (PubMed).
: "Small interference RNA targeting Krüppel-like factor 8 inhibits the renal carcinoma 786-0 cells growth in vitro and in vivo." in: Journal of cancer research and clinical oncology, Vol. 136, Issue 8, pp. 1255-65, (2010) (PubMed).
: "Up-regulation of Krüppel-like factor 8 promotes tumor invasion and indicates poor prognosis for hepatocellular carcinoma." in: Gastroenterology, Vol. 139, Issue 6, pp. 2146-2157.e12, (2010) (PubMed).
-
-
- KLF8 (Kruppel-Like Factor 8 (KLF8))
-
别名
- KLF8
-
背景
-
Background Information: KLF8 is abnormally expressed in female patients with X autosome translocation t(X,21)(p11.2,q22.3) and non-syndromic mental retardation.
Gene Name: Kruppel-like factor 8
Alternative Symbols: BKLF3, ZNF741
Protein Name: Krueppel-like factor 8
-
分子量
- 39kDa
-
基因ID
- 11279
-
NCBI登录号
- NP_009181
-
UniProt
- O95600
抗原
-