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Ki-67 抗体 (C-Term)

Name: Ki-67 抗体 (C-Term)
SKU: ABIN3042997
Availability: OutOfStock

This 兔多克隆 antibody specifically detects Ki-67 in WB. It exhibits reactivity toward 人. It has been mentioned in 44+ publications

Lane 3: Recombinant Human Ki67 Protein 2. (Ki-67 抗体 (C-Term))

1 image

(44 references)

产品编号 ABIN3042997

发货至: 中国

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Quick Overview for Ki-67 抗体 (C-Term) (ABIN3042997)

抗原

See all Ki-67 (MKI67) 抗体

Ki-67 (MKI67) (Antigen Identified By Monoclonal Antibody Ki-67 (MKI67))

适用

人

宿主

兔

克隆类型

多克隆

标记

This Ki-67 antibody is un-conjugated

应用范围

Western Blotting (WB)

Discover our top product MKI67 Primary Antibody

抗原表位
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AA 3234-3256, C-Term

原理

Anti-Ki67/MKI67 Antibody

序列

KKAEDNVCVK KIRTRSHRDS EDI

交叉反应（详细）

No cross-reactivity with other proteins

产品特性

Anti-Ki67/MKI67 Antibody (ABIN3042997). Tested in WB applications. This antibody reacts with Human. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.

纯化方法

Immunogen affinity purified.

免疫原

A synthetic peptide corresponding to a sequence at the C-terminus of human Ki67.

亚型

IgG
anti-Antigen Identified By Monoclonal Antibody Ki-67 (MKI67) (AA 1201-1300) antibody
MKI67 适用: 人, 小鼠, 大鼠, 兔, 山羊 ELISA, IHC (p), IF (p) 宿主: 兔 Polyclonal unconjugated

anti-Antigen Identified By Monoclonal Antibody Ki-67 (MKI67) (AA 2293-2478) antibody
MKI67 适用: 人 IHC, WB, FACS, IF, StM 宿主: 小鼠 Monoclonal MKI67-2461 unconjugated

anti-Antigen Identified By Monoclonal Antibody Ki-67 (MKI67) (AA 2293-2478) antibody
MKI67 适用: 人 IHC, WB, FACS, IF, StM 宿主: 小鼠 Monoclonal MKI67-2462 unconjugated

anti-Antigen Identified By Monoclonal Antibody Ki-67 (MKI67) (AA 1160-1493) antibody
MKI67 适用: 人 IHC, WB, IHC (p) 宿主: 大鼠 Monoclonal 9C3 unconjugated

anti-Antigen Identified By Monoclonal Antibody Ki-67 (MKI67) (AA 2815-2928) antibody
MKI67 适用: 人 IHC, WB, ICC, IP 宿主: 兔 Polyclonal unconjugated

anti-Antigen Identified By Monoclonal Antibody Ki-67 (MKI67) (AA 1160-1493) antibody
MKI67 适用: 人 IHC, WB, FACS, ELISA 宿主: 小鼠 Monoclonal 7B12B1 unconjugated

anti-Antigen Identified By Monoclonal Antibody Ki-67 (MKI67) antibody
MKI67 适用: 人, Cow IHC, WB, FACS, ICC 宿主: 小鼠 Polyclonal unconjugated

anti-Antigen Identified By Monoclonal Antibody Ki-67 (MKI67) (AA 2924-3256) antibody
MKI67 适用: 人 IHC, IHC (p) 宿主: 小鼠 Monoclonal 8H5 unconjugated

anti-Antigen Identified By Monoclonal Antibody Ki-67 (MKI67) (AA 1160-1493) antibody
MKI67 适用: 人 IHC, IHC (p) 宿主: 大鼠 Monoclonal 5B10 unconjugated

anti-Antigen Identified By Monoclonal Antibody Ki-67 (MKI67) (AA 2860-3256) antibody
MKI67 适用: 人 IHC, WB, IF, ICC 宿主: 兔 Polyclonal unconjugated

应用备注

Western blot, 0.1-0.5 μg/mL, Human

说明

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

限制

仅限研究用
状态

Lyophilized

溶解方式

Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

浓度

500 μg/mL

缓冲液

Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

储存液

Thimerosal (Merthiolate), Sodium azide

注意事项

This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

注意事项

Avoid repeated freezing and thawing.

储存条件

4 °C,-20 °C

储存方法

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

有效期

12 months
Lu, Wang, Zhang, Liu, Li, Zhang, Ye, Zhao, Zhao, Yan, Yang, Zhang, Li, Ren: "HER2-siRNA delivered by EGFR-specific single chain antibody inhibits NSCLC cell proliferation and tumor growth." in: Oncotarget, Vol. 7, Issue 17, pp. 23594-607, (2018) (PubMed).

Chen, Li, Peng, Jie, Dongye, Cai, Feng, Li, Zeng, Lun, Chen, Xu: "The induction of autophagy against mitochondria-mediated apoptosis in lung cancer cells by a ruthenium (II) imidazole complex." in: Oncotarget, Vol. 7, Issue 49, pp. 80716-80734, (2018) (PubMed).

Shi, Lv, Nie, Lu, Liu, Tian, Li, Zhang, Ren, Zhang, Kang: "Human nail stem cells are retained but hypofunctional during aging." in: Journal of molecular histology, Vol. 49, Issue 3, pp. 303-316, (2018) (PubMed).

Sun, Zhang, Wang, Shang, Zhou, Wang, Duan, Ruan, Gao, Dai, Qu, Liu, Ding, Wang, Wang, Dou: "MicroRNA-150 suppresses cell proliferation and metastasis in hepatocellular carcinoma by inhibiting the GAB1-ERK axis." in: Oncotarget, Vol. 7, Issue 10, pp. 11595-608, (2017) (PubMed).

Zhou, Wang, Xu, Wan, Qu, Fan, Chen, Sun, Liu: "Nek7 is overexpressed in hepatocellular carcinoma and promotes hepatocellular carcinoma cell proliferation in vitro and in vivo." in: Oncotarget, Vol. 7, Issue 14, pp. 18620-30, (2017) (PubMed).

Jiang, He, Wang, Zhang, Zhang, Yan, Wang, Che, Ke, Chen, Tong, Zhang, Wang, Li, Wan: "Mutant p53 induces EZH2 expression and promotes epithelial-mesenchymal transition by disrupting p68-Drosha complex assembly and attenuating miR-26a processing." in: Oncotarget, Vol. 6, Issue 42, pp. 44660-74, (2016) (PubMed).

Gao, Shen, He, Xiao: "GNRs@SiO₂-FA in combination with radiotherapy induces the apoptosis of HepG2 cells by modulating the expression of apoptosis-related proteins." in: International journal of molecular medicine, Vol. 36, Issue 5, pp. 1282-90, (2016) (PubMed).

Han, Wu, Wu, Huang, Cheng, Li, Sun, Xie, Zhou, Du: "Tumor-suppressive function of long noncoding RNA MALAT1 in glioma cells by downregulation of MMP2 and inactivation of ERK/MAPK signaling." in: Cell death & disease, Vol. 7, pp. e2123, (2016) (PubMed).

Zeng, Zhao, Ouyang, Zhao, Zhang, Chen, Yu, Lei: "Label-retaining assay enriches tumor-initiating cells in glioblastoma spheres cultivated in serum-free medium." in: Oncology letters, Vol. 12, Issue 2, pp. 815-824, (2016) (PubMed).

Li, Zeng, Qi, Tang, Zhang, Wu, Liang, Shi, Liu, Zhang: "Xenotransplantation of human adipose-derived stem cells in zebrafish embryos." in: PLoS ONE, Vol. 10, Issue 4, pp. e0123264, (2015) (PubMed).

Alsaegh, Miyashita, Zhu: "Expression of human papillomavirus is correlated with Ki-67 and COX-2 expressions in keratocystic odontogenic tumor." in: Pathology oncology research : POR, Vol. 21, Issue 1, pp. 65-71, (2015) (PubMed).

Li, Wang, Wu, Yang, Zhao, Chen, Xie, Li, Wei, Huang, Zhou, Du: "miR-494-3p Regulates Cellular Proliferation, Invasion, Migration, and Apoptosis by PTEN/AKT Signaling in Human Glioblastoma Cells." in: Cellular and molecular neurobiology, Vol. 35, Issue 5, pp. 679-87, (2015) (PubMed).

Liu, Wang, Wang: "Controllable organization and high throughput production of recoverable 3D tumors using pneumatic microfluidics." in: Lab on a chip, Vol. 15, Issue 4, pp. 1195-204, (2015) (PubMed).

Huang, Ma, Xu, Li, Li, Yue, Li, Guo, Qi: "Wnt2 promotes non-small cell lung cancer progression by activating WNT/?-catenin pathway." in: American journal of cancer research, Vol. 5, Issue 3, pp. 1032-46, (2015) (PubMed).

Cheng, Wang, Li, Wu, Han, Li, Chen, Xie, Huang, Du, Zhou: "MicroRNA-184 inhibits cell proliferation and invasion, and specifically targets TNFAIP2 in Glioma." in: Journal of experimental & clinical cancer research : CR, Vol. 34, pp. 27, (2015) (PubMed).

Xie, Zhu, Yang, Huang, Wu, Wang, Luo, Wang, Shao: "Solamargine triggers hepatoma cell death through apoptosis." in: Oncology letters, Vol. 10, Issue 1, pp. 168-174, (2015) (PubMed).

Yu, Chen, Su, Huo, Lin, Liao: "Factors influencing improvement of visual field after trans-sphenoidal resection of pituitary macroadenomas: a retrospective cohort study." in: International journal of ophthalmology, Vol. 8, Issue 6, pp. 1224-8, (2015) (PubMed).

Shan, Li, Newton, Zhao, Li, Guo: "A novel protein extracted from foxtail millet bran displays anti-carcinogenic effects in human colon cancer cells." in: Toxicology letters, Vol. 227, Issue 2, pp. 129-38, (2014) (PubMed).

Zhu, Liu, Li, Liu, Wang, Sun, Xiong, Jiang, Zheng, Hu: "Protein tyrosine phosphatase receptor U (PTPRU) is required for glioma growth and motility." in: Carcinogenesis, Vol. 35, Issue 8, pp. 1901-10, (2014) (PubMed).

Duan, Lin, Li, Ding, Qian, Zhang, Ge, Fan, Li: "Effects of inhibition of hedgehog signaling on cell growth and migration of uveal melanoma cells." in: Cancer biology & therapy, Vol. 15, Issue 5, pp. 544-59, (2014) (PubMed).

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抗原

Ki-67 (MKI67) (Antigen Identified By Monoclonal Antibody Ki-67 (MKI67))

别名

MKI67

背景

Synonyms: Antigen KI-67,MKI67,
Background: Ki-67 (Proliferation-related Ki-67 antigen), also known as MKI67 or KIA, is a protein that in humans is encoded by the MKI67 gene. From study of a panel of human-rodent somatic cell hybrids, Schonk et al. (1989) demonstrated that a gene involved in the expression of the MKI67 antigen is located on chromosome 10. By in situ hybridization, Fonatsch et al. (1991) regionalized the MKI67 gene to chromosome 10q25-qter. By FISH, Traut et al. (1998) mapped the mouse Mki67 gene to chromosome 7F3-F5. Antigen KI-67 is a nuclear protein that is associated with and may be necessary for cellular proliferation. Furthermore it is associated with ribosomal RNA transcription. Inactivation of antigen KI-67 leads to inhibition of ribosomal RNA synthesis.
Sequence Similarities: Contains 1 FHA domain.

分子量

22-24 kDa

UniProt

P46013

途径

Glycosaminoglycan Metabolic Process