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GLI2 抗体 (C-Term)

Name: GLI2 抗体 (C-Term)
SKU: ABIN3042988
Availability: OutOfStock

This anti-GLI2 antibody is a 兔多克隆 antibody detecting GLI2 in WB. Suitable for 人. This Primary Antibody has been cited in 1 publication.

Anti-Gli2 antibody, Western blotting WB: Human Placenta Tissue Lysate (GLI2 抗体 (C-Term))

Anti-Gli2 antibody, Western blotting Lane 1: MCF-7 Cell Lysate Lane 2: HELA Cell Lysate Lane 3: SKOV Cell Lysate Lane 4: Cell Lysate Lane 5: A549 Cell Lysate (GLI2 抗体 (C-Term))

2 images

(1 reference)

产品编号 ABIN3042988

发货至: 中国

Quick Overview for GLI2 抗体 (C-Term) (ABIN3042988)

抗原

See all GLI2 抗体

GLI2 (GLI Family Zinc Finger 2 (GLI2))

适用

人

宿主

兔

克隆类型

多克隆

标记

This GLI2 antibody is un-conjugated

应用范围

Western Blotting (WB)

Discover our top product GLI2 Primary Antibody

抗原表位
5

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1
AA 1444-1463, C-Term

原理

Anti-Zinc finger protein GLI2 Gli2 Antibody Picoband®

序列

MLYYYGQIHM YEQDGGLENL

交叉反应（详细）

No cross-reactivity with other proteins

产品特性

Anti-Zinc finger protein GLI2 Gli2 Antibody (ABIN3042988). Tested in WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

纯化方法

Immunogen affinity purified.

免疫原

A synthetic peptide corresponding to a sequence at the C-terminus of human Gli2.

亚型

IgG
anti-GLI Family Zinc Finger 2 (GLI2) (Middle Region) antibody
GLI2 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-GLI Family Zinc Finger 2 (GLI2) (AA 1287-1321), (C-Term) antibody
GLI2 适用: 人 WB, IHC (p), IF, FACS 宿主: 兔 Polyclonal RB49147 unconjugated

anti-GLI Family Zinc Finger 2 (GLI2) (C-Term) antibody
GLI2 适用: 人 WB, ELISA, IF, FACS 宿主: 兔 Polyclonal unconjugated

anti-GLI Family Zinc Finger 2 (GLI2) antibody
GLI2 适用: 人, 小鼠, 大鼠 IF 宿主: 兔 Polyclonal unconjugated

anti-GLI Family Zinc Finger 2 (GLI2) (AA 600-649) antibody
GLI2 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-GLI Family Zinc Finger 2 (GLI2) (AA 30-65) antibody
GLI2 适用: 人, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated

anti-GLI Family Zinc Finger 2 (GLI2) (Internal Region) antibody
GLI2 适用: 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated

anti-GLI Family Zinc Finger 2 (GLI2) (AA 2-20) antibody
GLI2 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated

anti-GLI Family Zinc Finger 2 (GLI2) (N-Term) antibody
GLI2 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-GLI Family Zinc Finger 2 (GLI2) antibody
GLI2 适用: 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated

应用备注

Western blot, 0.1-0.5 μg/mL, Human
1. Bertolacini, C. D. P., Ribeiro-Bicudo, L. A., Petrin, A., Richieri-Costa, A., Murray, J. C. Clinical findings in patients with GLI2 mutations--phenotypic variability. Clin. Genet. 81: 70-75, 2012. 2. Matsumoto, N., Fujimoto, M., Kato, R., Niikawa, N. Assignment of the human GLI2 gene to 2q14 by fluorescence in situ hybridization. Genomics 36: 220-221, 1996. 3. Roessler, E., Ermilov, A. N., Grange, D. K., Wang, A., Grachtchouk, M., Dlugosz, A. A., Muenke, M. A previously unidentified amino-terminal domain regulates transcriptional activity of wild-type and disease-associated human GLI2. Hum. Molec. Genet. 14: 2181-2188, 2005.

说明

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

限制

仅限研究用
状态

Lyophilized

溶解方式

Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

浓度

500 μg/mL

缓冲液

Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

储存液

Thimerosal (Merthiolate), Sodium azide

注意事项

This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

注意事项

Avoid repeated freezing and thawing.

储存条件

4 °C,-20 °C

储存方法

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

有效期

12 months
Xiang, Jiang, Guo, Gong, Yang, Wu, Huang, Cheng, Xu: "Hedgehog pathway inhibitor-4 suppresses malignant properties of chondrosarcoma cells by disturbing tumor ciliogenesis." in: Oncology reports, Vol. 32, Issue 4, pp. 1622-30, (2014) (PubMed).
抗原

GLI2 (GLI Family Zinc Finger 2 (GLI2))

别名

GLI2

背景

Synonyms: Zinc finger protein GLI2 ,GLI family zinc finger protein 2 ,Tax helper protein ,GLI2 ,THP ,
Tissue Specificity: Isoform 1 and isoform 4 are expressed in HTLV- 1-infected T-cell lines (at protein level). Isoform 1 and isoform 2 are strongly expressed in HTLV-1-infected T-cell lines. Isoform 3 and isoform 4 are weakly expressed in HTLV-1-infected T-cell lines. .
Background: GLI2 (Gli-Kruppel Family Member 2), also called ONCOGENE GLI2, is a protein that in humans is encoded by the GLI2 gene. Sequencing of GLI cDNA clones showed the presence of 5 tandem zinc fingers connected by histidine-cysteine links, which indicated that the gene belongs to the family of zinc finger genes related to Kruppel (Kr). The Drosophila gene Kr is a member of the gap class of segmentation genes, thoracic and anterior abdominal segments fail to form in Kr mutant embryos. By fluorescence in situ hybridization, Matsumoto et al. (1996) refined the assignment of the GLI2 gene to chromosome 2q14. Roessler et al. (2005) showed that GLI2-delta-N exhibited potent transcriptional activity in vivo: overexpression in mouse skin led to the formation of hedgehog-independent epithelial downgrowths resembling basal cell carcinomas, which in humans are associated with constitutive hedgehog signaling.
Sequence Similarities: Belongs to the GLI C2H2-type zinc-finger protein family.

分子量

89 kDa

UniProt

P10070

途径

Hedgehog Signaling, Dopaminergic Neurogenesis