LTK 抗体 (C-Term)
Quick Overview for LTK 抗体 (C-Term) (ABIN3042963)
抗原
See all LTK 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 850-864, C-Term
-
原理
- Anti-LTK Antibody Picoband®
-
序列
- RGLQPQNLWN PTYRS
-
交叉反应 （详细）
- No cross-reactivity with other proteins
-
产品特性
- Anti-LTK Antibody (ABIN3042963). Tested in WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
-
纯化方法
- Immunogen affinity purified.
-
免疫原
- A synthetic peptide corresponding to a sequence at the C-terminus of human LTK.
-
亚型
- IgG
-
-
anti-Leukocyte Receptor tyrosine Kinase (LTK) (Internal Region) antibody
LTK 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Leukocyte Receptor tyrosine Kinase (LTK) (AA 20-175) antibodyLTK 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Leukocyte Receptor tyrosine Kinase (LTK) (AA 355-460) antibodyLTK 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Leukocyte Receptor tyrosine Kinase (LTK) (AA 233-282) antibodyLTK 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Leukocyte Receptor tyrosine Kinase (LTK) (N-Term) antibodyLTK 适用: 人, 小鼠, 豚鼠, 兔 WB 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
-
Western blot, 0.1-0.5 μg/mL, Human
1. Li, N., Nakamura, K., Jiang, Y., Tsurui, H., Matsuoka, S., Abe, M., Ohtsuji, M., Nishimura, H., Kato, K., Kawai, T., Atsumi, T., Koike, T., Shirai, T., Ueno, H., Hirose, S. Gain-of-function polymorphism in mouse and human Ltk: implications for the pathogenesis of systemic lupus erythematosus. Hum. Molec. Genet. 13: 171-179, 2004. 2. Liao, X., Zhou, R., Gilbert, D. J., Copeland, N. G., Jenkins, N. A. Receptor tyrosine kinase gene Tyro3 maps to mouse chromosome 2, closely linked to Ltk. Mammalian Genome 7: 395-396, 1996. 3. Toyoshima, H., Kozutsumi, H., Maru, Y., Hagiwara, K., Furuya, A., Mioh, H., Hanai, N., Takaku, F., Yazaki, Y., Hirai, H. Differently spliced cDNAs of human leukocyte tyrosine kinase receptor tyrosine kinase predict receptor proteins with and without a tyrosine kinase domain and a soluble receptor protein. Proc. Nat. Acad. Sci. 90: 5404-5408, 1993. -
说明
-
Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
-
浓度
- 500 μg/mL
-
缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
-
储存液
- Thimerosal (Merthiolate), Sodium azide
-
注意事项
- This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
-
注意事项
- Avoid repeated freezing and thawing.
-
储存条件
- 4 °C,-20 °C
-
储存方法
-
Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles. -
有效期
- 12 months
-
-
- LTK (Leukocyte Receptor tyrosine Kinase (LTK))
-
别名
- LTK
-
背景
-
Synonyms: Leukocyte tyrosine kinase receptor,2.7.10.1,Protein tyrosine kinase 1,LTK,TYK1,
Tissue Specificity: Expressed in non-hematopoietic cell lines and T- and B-cell lines. .
Background: LTK (Leukocyte Tyrosine Kinase), also known as TYK1, is an enzyme that in humans is encoded by the LTK gene. The protein encoded by this gene is a member of the ALK/LTK receptor family of receptor tyrosine kinases (RTKs) whose ligand is unknown. Toyoshima et al. (1993) cloned a set of cDNAs representing differently spliced human LTK mRNAs. Liao et al. (1996) found that the mouse Ltk gene is closely linked to the Tyro3 gene which maps to mouse chromosome 2. Thus, the LTK gene produces not only the putative receptor tyrosine kinase for an unknown ligand but also multiple protein products that may have different functions.
Sequence Similarities: Belongs to the protein kinase superfamily. Tyr protein kinase family. Insulin receptor subfamily.
-
分子量
- 85-91 kDa
-
UniProt
- P29376
-
途径
- RTK signaling
抗原
-
