Cadherin 5 抗体 (C-Term)
(2 references)Quick Overview for Cadherin 5 抗体 (C-Term) (ABIN3042913)
抗原
See all Cadherin 5 (CDH5) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 766-784, C-Term
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原理
- Anti-VE-Cadherin CDH5-Antibody Picoband®
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序列
- RFKMLAELYG SDPREELLY
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交叉反应 （详细）
- No cross-reactivity with other proteins
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产品特性
- Anti-VE-Cadherin CDH5-Antibody (ABIN3042913). Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the C-terminus of human VE Cadherin, different from the related mouse and rat sequences by three amino acids.
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亚型
- IgG
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anti-Cadherin 5 (CDH5) (AA 601-700) antibody
CDH5 适用: 人, 小鼠, 大鼠 WB, ELISA, FACS, ICC, IHC (fro), IHC (p), IF (p), IF (cc) 宿主: 兔 Polyclonal unconjugated
anti-Cadherin 5 (CDH5) (AA 68-307) antibodyCDH5 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Cadherin 5 (CDH5) (AA 650-750) antibodyCDH5 适用: 人 WB, IHC, IP, IF 宿主: 兔 Polyclonal unconjugated
anti-Cadherin 5 (CDH5) (AA 29-223) antibodyCDH5 适用: 人, 小鼠 WB, ELISA, FACS 宿主: 小鼠 Monoclonal 3D5C7 unconjugated
anti-Cadherin 5 (CDH5) (C-Term) antibodyCDH5 适用: 人, 小鼠 WB, IHC, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Cadherin 5 (CDH5) (AA 766-784) antibodyCDH5 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Cadherin 5 (CDH5) (AA 251-320) antibodyCDH5 适用: 人, 小鼠 FACS, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Cadherin 5 (CDH5) (AA 59-382) antibodyCDH5 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Cadherin 5 (CDH5) (AA 259-358) antibodyCDH5 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Cadherin 5 (CDH5) antibodyCDH5 适用: 人 WB, FACS, IF, Func, IA 宿主: 小鼠 Monoclonal BV9 unconjugated
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应用备注
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Western blot, 0.1-0.5 μg/mL, Human
Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human, Mouse, Rat
1. Huber, P., Dalmon, J., Engiles, J., Breviario, F., Gory, S., Siracusa, L. D., Buchberg, A. M., Dejana, E. Genomic structure and chromosomal mapping of the mouse VE-cadherin gene (Cdh5). Genomics 32: 21-28, 1996. 2. Kremmidiotis, G., Baker, E., Crawford, J., Eyre, H. J., Nahmias, J., Callen, D. F. Localization of human cadherin genes to chromosome regions exhibiting cancer-related loss of heterozygosity. Genomics 49: 467-471, 1998. -
说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles. -
有效期
- 12 months
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: "Exposure to Concentrated Ambient Fine Particulate Matter Induces Vascular Endothelial Dysfunction via miR-21." in: International journal of biological sciences, Vol. 13, Issue 7, pp. 868-877, (2018) (PubMed).
: "Knockdown of protein tyrosine phosphatase receptor U inhibits growth and motility of gastric cancer cells." in: International journal of clinical and experimental pathology, Vol. 7, Issue 9, pp. 5750-61, (2014) (PubMed).
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: "Exposure to Concentrated Ambient Fine Particulate Matter Induces Vascular Endothelial Dysfunction via miR-21." in: International journal of biological sciences, Vol. 13, Issue 7, pp. 868-877, (2018) (PubMed).
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- Cadherin 5 (CDH5)
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别名
- CDH5
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背景
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Synonyms: Cadherin-5,7B4 antigen,Vascular endothelial cadherin,VE-cadherin,CD144,CDH5,
Tissue Specificity: Endothelial tissues and brain.
Background: CDH5 (Cadherin 5), also known as VE-cadherin, is a type of cadherin. It is encoded by the human gene CDH5. Kremmidiotis et al. (1998) mapped the human CDH5 gene to 16q22.1 using somatic cell hybrid panels. Functioning as a classic cadherin by imparting to cells the ability to adhere in a homophilic manner, the protein may play an important role in endothelial cell biology through control of the cohesion and organization of the intercellular junctions. Therefore it was concluded that VE-cadherin serves the purpose of maintaining newly formed vessels.
Sequence Similarities: Belongs to the annexin family.
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分子量
- 130 kDa
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UniProt
- P33151
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途径
- Cell-Cell Junction Organization, Signaling Events mediated by VEGFR1 and VEGFR2
抗原
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