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Cadherin 5 抗体 (C-Term)

Name: Cadherin 5 抗体 (C-Term)
SKU: ABIN3042913
Availability: OutOfStock

CDH5 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated

Western Blotting (WB) image for anti-Cadherin 5 (CDH5) (AA 766-784), (C-Term) antibody (ABIN3042913) (Cadherin 5 抗体 (C-Term))

Anti-VE Cadherin antibody, IHC(P) IHC(P): Human Lung Cancer Tissue (Cadherin 5 抗体 (C-Term))

IHC

Anti-VE Cadherin antibody, IHC(P) IHC(P): Rat Brain Tissue (Cadherin 5 抗体 (C-Term))

IHC

3 images

(2 references)

产品编号 ABIN3042913

发货至: 中国

Datasheet as PDF

抗原 See all Cadherin 5 (CDH5) 抗体

Cadherin 5 (CDH5)
抗原表位
15

12

9

7

6

4

3

3

3

3

3

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1
AA 766-784, C-Term
适用
92

52

40

3

2

2

1

1

1

1
人, 小鼠, 大鼠
宿主
77

31

4

1
兔
Compatible Secondaries
克隆类型
73

40
多克隆
标记
77

5

5

3

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
This Cadherin 5 antibody is un-conjugated
应用范围
91

44

37

37

31

28

14

13

13

12

10

5

4

2

1

1

1

1
Western Blotting (WB), Immunohistochemistry (IHC)

原理

Anti-VE-Cadherin CDH5-Antibody Picoband®

序列

RFKMLAELYG SDPREELLY

交叉反应（详细）

No cross-reactivity with other proteins

产品特性

Anti-VE-Cadherin CDH5-Antibody (ABIN3042913). Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

纯化方法

Immunogen affinity purified.

免疫原

A synthetic peptide corresponding to a sequence at the C-terminus of human VE Cadherin, different from the related mouse and rat sequences by three amino acids.

亚型

IgG

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CDH5 适用: 人 WB, IHC, IP, IF 宿主: 兔 Polyclonal unconjugated

anti-Cadherin 5 (CDH5) (AA 29-223) antibody
CDH5 适用: 人, 小鼠 WB, ELISA, FACS 宿主: 小鼠 Monoclonal 3D5C7 unconjugated

anti-Cadherin 5 (CDH5) (C-Term) antibody
CDH5 适用: 人, 小鼠 WB, IHC, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated

anti-Cadherin 5 (CDH5) (AA 766-784) antibody
CDH5 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Cadherin 5 (CDH5) (AA 251-320) antibody
CDH5 适用: 人, 小鼠 FACS, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Cadherin 5 (CDH5) (AA 59-382) antibody
CDH5 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Cadherin 5 (CDH5) antibody
CDH5 适用: 人 WB, FACS, IF, Func, IA 宿主: 小鼠 Monoclonal BV9 unconjugated

anti-Cadherin 5 (CDH5) (AA 29-223) antibody
CDH5 适用: 人, 大鼠 WB, ELISA, FACS 宿主: 小鼠 Monoclonal unconjugated

应用备注

Western blot, 0.1-0.5 μg/mL, Human
Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human, Mouse, Rat
1. Huber, P., Dalmon, J., Engiles, J., Breviario, F., Gory, S., Siracusa, L. D., Buchberg, A. M., Dejana, E. Genomic structure and chromosomal mapping of the mouse VE-cadherin gene (Cdh5). Genomics 32: 21-28, 1996. 2. Kremmidiotis, G., Baker, E., Crawford, J., Eyre, H. J., Nahmias, J., Callen, D. F. Localization of human cadherin genes to chromosome regions exhibiting cancer-related loss of heterozygosity. Genomics 49: 467-471, 1998.

说明

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

限制

仅限研究用
状态

Lyophilized

溶解方式

Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

浓度

500 μg/mL

缓冲液

Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

注意事项

Avoid repeated freezing and thawing.

储存条件

4 °C,-20 °C

储存方法

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

有效期

12 months
Dai, Chen, Lin, Wang, Guo, Zhang: "Exposure to Concentrated Ambient Fine Particulate Matter Induces Vascular Endothelial Dysfunction via miR-21." in: International journal of biological sciences, Vol. 13, Issue 7, pp. 868-877, (2018) (PubMed).

Liu, Zhu, Xiong, Zheng, Hu, Qiu: "Knockdown of protein tyrosine phosphatase receptor U inhibits growth and motility of gastric cancer cells." in: International journal of clinical and experimental pathology, Vol. 7, Issue 9, pp. 5750-61, (2014) (PubMed).
抗原

Cadherin 5 (CDH5)

别名

CDH5 (CDH5 产品)

背景

Synonyms: Cadherin-5,7B4 antigen,Vascular endothelial cadherin,VE-cadherin,CD144,CDH5,
Tissue Specificity: Endothelial tissues and brain.
Background: CDH5 (Cadherin 5), also known as VE-cadherin, is a type of cadherin. It is encoded by the human gene CDH5. Kremmidiotis et al. (1998) mapped the human CDH5 gene to 16q22.1 using somatic cell hybrid panels. Functioning as a classic cadherin by imparting to cells the ability to adhere in a homophilic manner, the protein may play an important role in endothelial cell biology through control of the cohesion and organization of the intercellular junctions. Therefore it was concluded that VE-cadherin serves the purpose of maintaining newly formed vessels.
Sequence Similarities: Belongs to the annexin family.

分子量

130 kDa

UniProt

P33151

途径

Cell-Cell Junction Organization, Signaling Events mediated by VEGFR1 and VEGFR2