CXCR1 抗体 (N-Term)
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Quick Overview for CXCR1 抗体 (N-Term) (ABIN3042912)
抗原
See all CXCR1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 24-38, N-Term
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原理
- Anti-CXCR1 Antibody
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序列
- DEDYSPCMLE TETLN
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交叉反应 （详细）
- No cross-reactivity with other proteins
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产品特性
- Anti-CXCR1 Antibody (ABIN3042912). Tested in Flow Cytometry, WB applications. This antibody reacts with Human. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the N-terminus of human CXCR1.
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亚型
- IgG
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anti-Chemokine (C-X-C Motif) Receptor 1 (CXCR1) (C-Term) antibody
KO Validated CXCR1 适用: 人 IHC (p), ICC, IF, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-X-C Motif) Receptor 1 (CXCR1) (AA 186-280) antibodyCXCR1 适用: 人, 大鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-X-C Motif) Receptor 1 (CXCR1) (AA 250-350) antibodyCXCR1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-X-C Motif) Receptor 1 (CXCR1) antibodyCXCR1 适用: 人, 大鼠, 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-X-C Motif) Receptor 1 (CXCR1) antibodyCXCR1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-X-C Motif) Receptor 1 (CXCR1) antibodyCXCR1 适用: 人, 大鼠, 小鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-X-C Motif) Receptor 1 (CXCR1) antibodyCXCR1 适用: 人 ELISA 宿主: 小鼠 Monoclonal 2B8A1 unconjugated
anti-Chemokine (C-X-C Motif) Receptor 1 (CXCR1) (AA 2-16), (Extracellular) antibodyCXCR1 适用: 人 WB, FACS, LCI 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-X-C Motif) Receptor 1 (CXCR1) antibodyCXCR1 适用: 人 FACS 宿主: 兔 Chimeric unconjugated Fc fragment
anti-Chemokine (C-X-C Motif) Receptor 1 (CXCR1) (AA 26-38) antibodyVerified CXCR1 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
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应用备注
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Western blot, 0.1-0.5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
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说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles. -
有效期
- 12 months
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- CXCR1 (Chemokine (C-X-C Motif) Receptor 1 (CXCR1))
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别名
- CXCR1
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背景
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Synonyms: C-X-C chemokine receptor type 1,CXC-R1,CXCR-1,CDw128a,High affinity interleukin-8 receptor A,IL-8R A,IL-8 receptor type 1,CD181,CXCR1,CMKAR1, IL8RA,
Tissue Specificity: Endothelial tissues and brain.
Background: CXCR1 (Chemokine,CXC Motif, Receptor 1), also known as IL8RA or IL8R1, is a chemokine receptor. IL8RA is its human gene. Morris et al. (1992) mapped the IL8RA gene to chromosome 2q35. Hartl et al. (2007) concluded that CXCR1 cleavage and its functional consequences represent an important pathophysiologic mechanism in CF and other neutrophilic airway diseases. Receptor to interleukin-8, which is a powerful neutrophils chemotactic factor. Binding of IL-8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activate a phosphatidylinositol-calcium second messenger system. This receptor binds to IL-8 with a high affinity and to MGSA (GRO) with a low affinity.
Sequence Similarities: Belongs to the G-protein coupled receptor 1 family.
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分子量
- 50 kDa
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UniProt
- P25024
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途径
- cAMP Metabolic Process
抗原
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