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CXCR1 抗体 (N-Term)

This anti-CXCR1 antibody is a 兔多克隆 antibody detecting CXCR1 in WB 和 FACS. Suitable for 人.

Anti-CXCR1 antibody, IHC(P) IHC(P): Human Lung Cancer Tissue (CXCR1 抗体 (N-Term))

Western Blotting (WB) image for anti-Chemokine (C-X-C Motif) Receptor 1 (CXCR1) (AA 24-38), (N-Term) antibody (ABIN3042912) (CXCR1 抗体 (N-Term))

2 images

产品编号 ABIN3042912

发货至: 中国

Quick Overview for CXCR1 抗体 (N-Term) (ABIN3042912)

抗原

See all CXCR1 抗体

CXCR1 (Chemokine (C-X-C Motif) Receptor 1 (CXCR1))

适用

人

宿主

兔

克隆类型

多克隆

标记

32
5
5
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1

This CXCR1 antibody is un-conjugated

应用范围

44
20
19
19
15
13
13
10
7
7
4
1
1
1

Western Blotting (WB), Flow Cytometry (FACS)

Discover our top product CXCR1 Primary Antibody

抗原表位
15

6

4

2

2

1

1

1

1

1

1

1

1

1

1

1
AA 24-38, N-Term

原理

Anti-CXCR1 Antibody Picoband®

序列

DEDYSPCMLE TETLN

交叉反应（详细）

No cross-reactivity with other proteins

产品特性

Anti-CXCR1 Antibody (ABIN3042912). Tested in Flow Cytometry, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

纯化方法

Immunogen affinity purified.

免疫原

A synthetic peptide corresponding to a sequence at the N-terminus of human CXCR1.

亚型

IgG
anti-Chemokine (C-X-C Motif) Receptor 1 (CXCR1) (C-Term) antibody
KO Validated CXCR1 适用: 人 ICC, IHC (p), IF, IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Chemokine (C-X-C Motif) Receptor 1 (CXCR1) (AA 186-280) antibody
CXCR1 适用: 人, 大鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Chemokine (C-X-C Motif) Receptor 1 (CXCR1) antibody
CXCR1 适用: 人, 大鼠, 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Chemokine (C-X-C Motif) Receptor 1 (CXCR1) (AA 250-350) antibody
CXCR1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Chemokine (C-X-C Motif) Receptor 1 (CXCR1) (AA 1-50) antibody
CXCR1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated

anti-Chemokine (C-X-C Motif) Receptor 1 (CXCR1) antibody
CXCR1 适用: 人, 大鼠, 小鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Chemokine (C-X-C Motif) Receptor 1 (CXCR1) antibody
CXCR1 适用: 人 ELISA 宿主: 小鼠 Monoclonal 2B8A1 unconjugated

anti-Chemokine (C-X-C Motif) Receptor 1 (CXCR1) antibody
CXCR1 适用: 人 FACS 宿主: 兔 Chimeric unconjugated Fc fragment

anti-Chemokine (C-X-C Motif) Receptor 1 (CXCR1) (AA 26-38) antibody
Verified CXCR1 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated

anti-Chemokine (C-X-C Motif) Receptor 1 (CXCR1) (N-Term) antibody
CXCR1 适用: 人 WB, ELISA, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated

应用备注

Western blot, 0.1-0.5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
1. Hartl, D., Latzin, P., Hordijk, P., Marcos, V., Rudolph, C., Woischnik, M., Krauss-Etschmann, S., Koller, B., Reinhardt, D., Roscher, A. A., Roos, D., Griese, M. Cleavage of CXCR1 on neutrophils disables bacterial killing in cystic fibrosis lung disease. Nature Med. 13: 1423-1430, 2007. 2. Morris, S. W., Nelson, N., Valentine, M. B., Shapiro, D. N., Look, A. T., Kozlosky, C. J., Beckmann, M. P., Cerretti, D. P. Assignment of the genes encoding human interleukin-8 receptor types 1 and 2 and an interleukin-8 receptor pseudogene to chromosome 2q35. Genomics 14: 685-691, 1992. 3. Vasilescu, A., Terashima, Y., Enomoto, M., Heath, S., Poonpiriya, V., Gatanaga, H., Do, H., Diop, G., Hirtzig, T., Auewarakul, P., Lauhakirti, D., Sura, T., Charneau, P., Marullo, S., Therwath, A., Oka, S., Kanegasaki, S., Lathrop, M., Matsushima, K., Zagury, J.-F., Matsuda, F. A haplotype of the human CXCR1 gene protective against rapid disease progression in HIV-1+ patients. Proc. Nat. Acad. Sci. 104: 3354-3359, 2007.

说明

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

限制

仅限研究用
状态

Lyophilized

溶解方式

Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

浓度

500 μg/mL

缓冲液

Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

注意事项

Avoid repeated freezing and thawing.

储存条件

4 °C,-20 °C

储存方法

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

有效期

12 months
抗原

CXCR1 (Chemokine (C-X-C Motif) Receptor 1 (CXCR1))

别名

CXCR1

背景

Synonyms: C-X-C chemokine receptor type 1,CXC-R1,CXCR-1,CDw128a,High affinity interleukin-8 receptor A,IL-8R A,IL-8 receptor type 1,CD181,CXCR1,CMKAR1, IL8RA,
Tissue Specificity: Endothelial tissues and brain.
Background: CXCR1 (Chemokine,CXC Motif, Receptor 1), also known as IL8RA or IL8R1, is a chemokine receptor. IL8RA is its human gene. Morris et al. (1992) mapped the IL8RA gene to chromosome 2q35. Hartl et al. (2007) concluded that CXCR1 cleavage and its functional consequences represent an important pathophysiologic mechanism in CF and other neutrophilic airway diseases. Receptor to interleukin-8, which is a powerful neutrophils chemotactic factor. Binding of IL-8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activate a phosphatidylinositol-calcium second messenger system. This receptor binds to IL-8 with a high affinity and to MGSA (GRO) with a low affinity.
Sequence Similarities: Belongs to the G-protein coupled receptor 1 family.

分子量

50 kDa

UniProt

P25024

途径

cAMP Metabolic Process

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