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BAG2 抗体 (N-Term)

BAG2 适用: 人, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3042900
发货至: 中国
  • 抗原 See all BAG2 抗体
    BAG2 (BCL2-Associated Athanogene 2 (BAG2))
    抗原表位
    • 15
    • 14
    • 11
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 1-14, N-Term
    适用
    • 53
    • 25
    • 11
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    人, 大鼠
    宿主
    • 49
    • 5
    • 1
    克隆类型
    • 50
    • 4
    多克隆
    标记
    • 31
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This BAG2 antibody is un-conjugated
    应用范围
    • 51
    • 25
    • 21
    • 13
    • 13
    • 9
    • 3
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB)
    原理
    Rabbit IgG polyclonal antibody for BAG family molecular chaperone regulator 2(BAG2) detection. Tested with WB in Human,Mouse,Rat.
    序列
    MAQAKINAKA NEGR
    交叉反应 (详细)
    Predicted Cross Reactivity: mouse
    No cross reactivity with other proteins.
    Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities.
    产品特性
    Rabbit IgG polyclonal antibody for BAG family molecular chaperone regulator 2(BAG2) detection. Tested with WB in Human,Mouse,Rat.
    Gene Name: BCL2-associated athanogene 2
    Protein Name: BAG family molecular chaperone regulator 2
    纯化方法
    Immunogen affinity purified.
    免疫原
    A synthetic peptide corresponding to a sequence at the N-terminus of human BAG2(1-14aa MAQAKINAKANEGR), different from the related mouse and rat sequences by two amino acids.
    亚型
    IgG
    Top Product
    Discover our top product BAG2 Primary Antibody
  • 应用备注
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat, Predicted Species: Mouse, The detection limit for BAG2 is approximately 0.5 ng/lane under reducing conditions.
    Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities.
    Other applications have not been tested. Optimal dilutions should be determined by end users.
    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    浓度
    500 μg/mL
    缓冲液
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
    储存液
    Thimerosal (Merthiolate), Sodium azide
    注意事项
    This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
    有效期
    12 months
  • 抗原
    BAG2 (BCL2-Associated Athanogene 2 (BAG2))
    别名
    BAG2 (BAG2 产品)
    别名
    bag2 antibody, MGC89300 antibody, BAG2 antibody, ATBAG2 antibody, BCL-2-associated athanogene 2 antibody, MTG10.13 antibody, MTG10_13 antibody, BAG-2 antibody, dJ417I1.2 antibody, zgc:64195 antibody, 2610042A13Rik antibody, BC016230 antibody, BCL2 associated athanogene 2 antibody, BCL-2-associated athanogene 2 antibody, BCL2-associated athanogene 2 antibody, Bcl2-associated athanogene 2 antibody, bag2 antibody, BAG2 antibody, Bag2 antibody
    背景
    BAG family molecular chaperone regulator 2 is a protein that in humans is encoded by the BAG2 gene. The predicted BAG2 protein contains 211 amino acids. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner. The functional antagonisms displayed between BAG family proteins and Hip suggest that a proper balance of these 2 types of protein is required for achieving optimal cycles of substrate binding and release required for inducting conformational changes in proteins, with Hip promoting peptide substrate binding by Hsc70/Hsp70 and BAG family proteins promoting dissociation.

    Synonyms: BAG 2 antibody|BAG family molecular chaperone regulator 2 antibody|BAG-2 antibody|BAG-family molecular chaperone regulator-2 antibody|Bag2 antibody|BAG2_HUMAN antibody|BCL 2 associated athanogene 2 antibody|Bcl-2-associated athanogene 2 antibody|BCL2 associated athanogene 2 antibody|BCL2-associated athanogene 2 antibody|dJ417I1.2(BAG family molecular chaperone regulator 2) antibody|dJ417I1.2 antibody|KIAA0576 antibody|MGC149462 antibody|OTTHUMP00000016668 antibody
    UniProt
    O95816
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